Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- ABIN1882287 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1) (C-Term) antibody
- Antibody type
- Monoclonal
- Antigen
- This UCHL1 Monoclonal antibody is generated from mouses immunized with a KLH conjugated synthetic peptide selected from the 185-214 region of human UCHL1.
- Description
- This antibody is purified through a protein G column, followed by dialysis against PBS.
- Reactivity
- Human, Rat
- Host
- Mouse
- Epitope
- C-Term
- Isotype
- IgG
- Antibody clone number
- 696CT2-1-4
- Vial size
- 400 μL
- Concentration
- 0.26 mg/mL
Submitted references Ubiquitin vinyl methyl ester binding orients the misaligned active site of the ubiquitin hydrolase UCHL1 into productive conformation.
Oxidative modifications and down-regulation of ubiquitin carboxyl-terminal hydrolase L1 associated with idiopathic Parkinson's and Alzheimer's diseases.
The structure of the human gene encoding protein gene product 9.5 (PGP9.5), a neuron-specific ubiquitin C-terminal hydrolase.
Boudreaux DA, Maiti TK, Davies CW, Das C
Proceedings of the National Academy of Sciences of the United States of America 2010 May 18;107(20):9117-22
Proceedings of the National Academy of Sciences of the United States of America 2010 May 18;107(20):9117-22
Oxidative modifications and down-regulation of ubiquitin carboxyl-terminal hydrolase L1 associated with idiopathic Parkinson's and Alzheimer's diseases.
Choi J, Levey AI, Weintraub ST, Rees HD, Gearing M, Chin LS, Li L
The Journal of biological chemistry 2004 Mar 26;279(13):13256-64
The Journal of biological chemistry 2004 Mar 26;279(13):13256-64
The structure of the human gene encoding protein gene product 9.5 (PGP9.5), a neuron-specific ubiquitin C-terminal hydrolase.
Day IN, Hinks LJ, Thompson RJ
The Biochemical journal 1990 Jun 1;268(2):521-4
The Biochemical journal 1990 Jun 1;268(2):521-4
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Supportive validation
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- antibodies-online (provider)
- Main image
- Experimental details
- UCHL1 Antibody (C-term) (ABIN1882287) western blot analysis in 293T,NCI-H1299,rat PC-12 cell line lysates (35 μg/lane). This demonstrates the UCHL1 antibody detected the UCHL1 protein (arrow).