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- Product number
- ABIN371848 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1) antibody
- Antibody type
- Monoclonal
- Antigen
- Recombinant full length human UCHL1 purified from E. coli.
- Description
- Supernatant
- Reactivity
- Human, Mouse, Rat, Bovine
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- BH7
- Vial size
- 0.1 mL
- Storage
- Store the antibody undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Submitted references The UCH-L1 gene encodes two opposing enzymatic activities that affect alpha-synuclein degradation and Parkinson's disease susceptibility.
Loss of Uch-L1 and Uch-L3 leads to neurodegeneration, posterior paralysis and dysphagia.
The neuron-specific protein PGP 9.5 is a ubiquitin carboxyl-terminal hydrolase.
Isolation of PGP 9.5, a new human neurone-specific protein detected by high-resolution two-dimensional electrophoresis.
Liu Y, Fallon L, Lashuel HA, Liu Z, Lansbury PT Jr
Cell 2002 Oct 18;111(2):209-18
Cell 2002 Oct 18;111(2):209-18
Loss of Uch-L1 and Uch-L3 leads to neurodegeneration, posterior paralysis and dysphagia.
Kurihara LJ, Kikuchi T, Wada K, Tilghman SM
Human molecular genetics 2001 Sep 1;10(18):1963-70
Human molecular genetics 2001 Sep 1;10(18):1963-70
The neuron-specific protein PGP 9.5 is a ubiquitin carboxyl-terminal hydrolase.
Wilkinson KD, Lee KM, Deshpande S, Duerksen-Hughes P, Boss JM, Pohl J
Science (New York, N.Y.) 1989 Nov 3;246(4930):670-3
Science (New York, N.Y.) 1989 Nov 3;246(4930):670-3
Isolation of PGP 9.5, a new human neurone-specific protein detected by high-resolution two-dimensional electrophoresis.
Doran JF, Jackson P, Kynoch PA, Thompson RJ
Journal of neurochemistry 1983 Jun;40(6):1542-7
Journal of neurochemistry 1983 Jun;40(6):1542-7
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- Experimental details
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Image(s): Immunofluorescence
