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- Antigen structure
- References [7]
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- Validations
- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 13659-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13659-1-AP, RRID:AB_2107937
- Product name
- GART antibody
- Antibody type
- Polyclonal
- Description
- GART antibody (Cat. #13659-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references GART Functions as a Novel Methyltransferase in the RUVBL1/β-Catenin Signaling Pathway to Promote Tumor Stemness in Colorectal Cancer.
Purine nucleotide depletion prompts cell migration by stimulating the serine synthesis pathway.
Mitochondrial NADP(+) is essential for proline biosynthesis during cell growth.
UHMK1 promotes gastric cancer progression through reprogramming nucleotide metabolism.
ERK2 Phosphorylates PFAS to Mediate Posttranslational Control of De Novo Purine Synthesis.
Purine Nucleotide Availability Regulates mTORC1 Activity through the Rheb GTPase.
mTORC1 induces purine synthesis through control of the mitochondrial tetrahydrofolate cycle.
Tang C, Ke M, Yu X, Sun S, Luo X, Liu X, Zhou Y, Wang Z, Cui X, Gu C, Yang Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Sep;10(25):e2301264
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Sep;10(25):e2301264
Purine nucleotide depletion prompts cell migration by stimulating the serine synthesis pathway.
Soflaee MH, Kesavan R, Sahu U, Tasdogan A, Villa E, Djabari Z, Cai F, Tran DH, Vu HS, Ali ES, Rion H, O'Hara BP, Kelekar S, Hallett JH, Martin M, Mathews TP, Gao P, Asara JM, Manning BD, Ben-Sahra I, Hoxhaj G
Nature communications 2022 May 16;13(1):2698
Nature communications 2022 May 16;13(1):2698
Mitochondrial NADP(+) is essential for proline biosynthesis during cell growth.
Tran DH, Kesavan R, Rion H, Soflaee MH, Solmonson A, Bezwada D, Vu HS, Cai F, Phillips JA 3rd, DeBerardinis RJ, Hoxhaj G
Nature metabolism 2021 Apr;3(4):571-585
Nature metabolism 2021 Apr;3(4):571-585
UHMK1 promotes gastric cancer progression through reprogramming nucleotide metabolism.
Feng X, Ma D, Zhao J, Song Y, Zhu Y, Zhou Q, Ma F, Liu X, Zhong M, Liu Y, Xiong Y, Qiu X, Zhang Z, Zhang H, Zhao Y, Zhang K, Hong X, Zhang Z
The EMBO journal 2020 Mar 2;39(5):e102541
The EMBO journal 2020 Mar 2;39(5):e102541
ERK2 Phosphorylates PFAS to Mediate Posttranslational Control of De Novo Purine Synthesis.
Ali ES, Sahu U, Villa E, O'Hara BP, Gao P, Beaudet C, Wood AW, Asara JM, Ben-Sahra I
Molecular cell 2020 Jun 18;78(6):1178-1191.e6
Molecular cell 2020 Jun 18;78(6):1178-1191.e6
Purine Nucleotide Availability Regulates mTORC1 Activity through the Rheb GTPase.
Emmanuel N, Ragunathan S, Shan Q, Wang F, Giannakou A, Huser N, Jin G, Myers J, Abraham RT, Unsal-Kacmaz K
Cell reports 2017 Jun 27;19(13):2665-2680
Cell reports 2017 Jun 27;19(13):2665-2680
mTORC1 induces purine synthesis through control of the mitochondrial tetrahydrofolate cycle.
Ben-Sahra I, Hoxhaj G, Ricoult SJH, Asara JM, Manning BD
Science (New York, N.Y.) 2016 Feb 12;351(6274):728-733
Science (New York, N.Y.) 2016 Feb 12;351(6274):728-733
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HepG2 cells were subjected to SDS PAGE followed by western blot with 13659-1-AP(GART antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human cervical cancer using 13659-1-AP(GART antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The GART antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human GART. This antibody recognizes human, mouse, rat antigen. The GART antibody has been validated for the following applications: ELISA, WB, IHC analysis.
