Antibody data
- Antibody Data
 - Antigen structure
 - References [2]
 - Comments [0]
 - Validations
 - Immunocytochemistry [1]
 - Immunohistochemistry [1]
 
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Validation data
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- Product number
 - HPA019371 - Provider product page

 - Provider
 - Atlas Antibodies
 - Proper citation
 - Atlas Antibodies Cat#HPA019371, RRID:AB_1844519
 - Product name
 - Anti-ACO1
 - Antibody type
 - Polyclonal
 - Description
 - Polyclonal Antibody against Human ACO1, Gene description: aconitase 1, soluble, Alternative Gene Names: IREB1, IREBP, IRP1, Validated applications: WB, IHC, ICC, Uniprot ID: P21399, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
 - Reactivity
 - Human, Mouse, Rat
 - Host
 - Rabbit
 - Conjugate
 - Unconjugated
 - Isotype
 - IgG
 - Vial size
 - 100 µl
 - Concentration
 - 0.1 mg/ml
 - Storage
 - Store at +4°C for short term storage. Long time storage is recommended at -20°C.
 - Handling
 - The antibody solution should be gently mixed before use.
 
Submitted references		Anti-Inflammatory CDGSH Iron-Sulfur Domain 2: A Biomarker of Central Nervous System Insult in Cellular, Animal Models and Patients
				
Dysregulation of IRP1-Mediated Iron Metabolism Causes Gamma Ray-specific Radioresistance in Leukemia Cells
				
		
	
			Kung W, Lin C, Chen W, Jiang L, Sun Y, Hsieh K, Lin M
Biomedicines 2022;10(4):777
		Biomedicines 2022;10(4):777
Dysregulation of IRP1-Mediated Iron Metabolism Causes Gamma Ray-specific Radioresistance in Leukemia Cells
			Heymann D, Haro K, Sheth A, Scheinberg D
PLoS ONE 2012;7(11):e48841
		PLoS ONE 2012;7(11):e48841
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					Supportive validation
					
									
				
				- Submitted by
 - Atlas Antibodies (provider)
 - Main image
 
- Experimental details
 - Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol & mitochondria.
 - Sample type
 - Human
 
							
					Supportive validation
					
									
				
		
		- Submitted by
 - Atlas Antibodies (provider)
 - Enhanced method
 - Orthogonal validation
 - Main image
 
- Experimental details
 - Immunohistochemistry analysis in human kidney and skeletal muscle tissues using HPA019371 antibody. Corresponding ACO1 RNA-seq data are presented for the same tissues.
 - Sample type
 - Human
 - Protocol
 - Protocol