PAB4771

antibody from Abnova Corporation

Targeting: MLLT3 AF-9, AF9, YEATS3

Western blot (Supportive data in Antibodypedia)

Antibody Data

Product number

PAB4771

Provider

Abnova Corporation

Proper citation

Abnova Corporation Cat#PAB4771, RRID:AB_1577322

Product name

MLLT3 polyclonal antibody

Antibody type

Polyclonal

Description

Rabbit polyclonal antibody raised against synthetic peptide of MLLT3.

Storage

Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

References

Submitted references

DNA structural properties of AF9 are similar to MLL and could act as recombination hot spots resulting in MLL/AF9 translocations and leukemogenesis.

Strissel PL, Strick R, Tomek RJ, Roe BA, Rowley JD, Zeleznik-Le NJ
Human molecular genetics 2000 Jul 1;9(11):1671-9

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MLLT3 gene on 9p22 involved in t(9;11) leukemia encodes a serine/proline rich protein homologous to MLLT1 on 19p13.

Iida S, Seto M, Yamamoto K, Komatsu H, Tojo A, Asano S, Kamada N, Ariyoshi Y, Takahashi T, Ueda R
Oncogene 1993 Nov;8(11):3085-92

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Genes on chromosomes 4, 9, and 19 involved in 11q23 abnormalities in acute leukemia share sequence homology and/or common motifs.

Nakamura T, Alder H, Gu Y, Prasad R, Canaani O, Kamada N, Gale RP, Lange B, Crist WM, Nowell PC
Proceedings of the National Academy of Sciences of the United States of America 1993 May 15;90(10):4631-5

Western blot

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

The MLLT3 polyclonal antibody (Cat # PAB4771) is used in Western blot to detect MLLT3 in HL-60 cell lysate