NBP1-97590
antibody from Novus Biologicals
Targeting: DIABLO
DFNA64, DIABLO-S, FLJ10537, FLJ25049, SMAC
Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
Reference
Comment
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- Product number
- NBP1-97590 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NBP1-97590, RRID:AB_11188892
- Product name
- Rat Monoclonal SMAC/Diablo Antibody
- Antibody type
- Monoclonal
- Description
- Protein G purified.
- Reactivity
- Mouse
- Host
- Rat
- Isotype
- IgG
- Vial size
- 0.05 mg
- Concentration
- 1.0 mg/ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references Mesenchymal stem cells expressing interleukin-18 inhibit breast cancer in a mouse model.
Treatment of mice with 2,3,7,8-tetrachlorodibenzo-p-dioxin leads to aryl hydrocarbon receptor-dependent nuclear translocation of NF-kappaB and expression of Fas ligand in thymic stromal cells and consequent apoptosis in T cells.
Treatment of mice with 2,3,7,8-tetrachlorodibenzo-p-dioxin leads to aryl hydrocarbon receptor-dependent nuclear translocation of NF-kappaB and expression of Fas ligand in thymic stromal cells and consequent apoptosis in T cells.
Tissue distribution of Diablo/Smac revealed by monoclonal antibodies.
Bcl-rambo, a novel Bcl-2 homologue that induces apoptosis via its unique C-terminal extension.
Liu X, Hu J, Li Y, Cao W, Wang Y, Ma Z, Li F
Oncology letters 2018 May;15(5):6265-6274
Oncology letters 2018 May;15(5):6265-6274
Treatment of mice with 2,3,7,8-tetrachlorodibenzo-p-dioxin leads to aryl hydrocarbon receptor-dependent nuclear translocation of NF-kappaB and expression of Fas ligand in thymic stromal cells and consequent apoptosis in T cells.
Camacho IA, Singh N, Hegde VL, Nagarkatti M, Nagarkatti PS
Journal of immunology (Baltimore, Md. : 1950) 2005 Jul 1;175(1):90-103
Journal of immunology (Baltimore, Md. : 1950) 2005 Jul 1;175(1):90-103
Treatment of mice with 2,3,7,8-tetrachlorodibenzo-p-dioxin leads to aryl hydrocarbon receptor-dependent nuclear translocation of NF-kappaB and expression of Fas ligand in thymic stromal cells and consequent apoptosis in T cells.
Camacho IA, Singh N, Hegde VL, Nagarkatti M, Nagarkatti PS
Journal of immunology (Baltimore, Md. : 1950) 2005 Jul 1;175(1):90-103
Journal of immunology (Baltimore, Md. : 1950) 2005 Jul 1;175(1):90-103
Tissue distribution of Diablo/Smac revealed by monoclonal antibodies.
Tikoo A, O'Reilly L, Day CL, Verhagen AM, Pakusch M, Vaux DL
Cell death and differentiation 2002 Jul;9(7):710-6
Cell death and differentiation 2002 Jul;9(7):710-6
Bcl-rambo, a novel Bcl-2 homologue that induces apoptosis via its unique C-terminal extension.
Kataoka T, Holler N, Micheau O, Martinon F, Tinel A, Hofmann K, Tschopp J
The Journal of biological chemistry 2001 Jun 1;276(22):19548-54
The Journal of biological chemistry 2001 Jun 1;276(22):19548-54
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: Smac Antibody (9H10) [NBP1-97590] - Detection of endogenous and over-expressed DIABLO. When analysis of endogenous DIABLO (50 to 100ug total protein per lane) in healthy cells of human as well as mouse origin is performed, only the processed form of mouse DIABLO (NIH3T3 and FDCP1 mouse cell lines) can be detected. The processed form of mouse DIABLO is detectable when over-expressed in human 293T cells serving as a positive control. The HA-tagged mDIABLO migrates at a slightly higher molecular weight than endogenous wild type mouse DIABLO (mouse testes).
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Smac Antibody (9H10) [NBP1-97590] - Detection of mouse Smac/DIABLO by clone 9H10.