RB-02-0029B-50
antibody from RayBiotech, Inc.
Targeting: DIABLO
DFNA64, DIABLO-S, FLJ10537, FLJ25049, SMAC
Antibody data
- Antibody Data
- Antigen structure
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- Validations [0]
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- Product number
- RB-02-0029B-50 - Provider product page
- Provider
- RayBiotech, Inc.
- Product name
- Rabbit Anti-Human SMAC [+Biotin]
- Antibody type
- Polyclonal
- Antigen
- a synthetic peptide (SMAC).
- Description
- Second mitochondria-derived activator of caspases, SMAC is a mitochondrial protein that promotes cytochrome-c dependent activation by eliminating the inhibition via IAP - a protein that negatively regulates apoptosis or programmed cell death. Smac is normally a mitochondrial protein but is found in the cytosol when a cell is primed for apoptosis by the final execution step of caspase activation. Smac is the second protein in the apoptosis link, along with cytochrome c, that promotes apoptosis by activating caspases. SMAC is an inhibitor of apoptosis protein (IAP)-binding protein. This mitochondrial protein enters the cytosol when cells undergo apoptosis, and it moderates the caspase inhibition of IAPs. This antibody was produced from a rabbit immunized with this peptide conjugated with KLH. The IgG fraction was purified from rabbit serum by Protein G affinity chromatography.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Biotin
- Antigen sequence
This antibody was produced from a r
abbit immunized with this peptide c
onjugated with KLH. The IgG fractio
n was purified from rabbit serum by
Protein G affinity chromatography.- Isotype
- IgG
- Vial size
- 50 µg
- Handling
- Product is supplied as a powder obtained from lyophilization of purified antibody in PBS without preservatives. Reconstitute the antibody with sterile 1 x PBS to a final concentration of 1 mg/ml.
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