10434-1-AP
antibody from Proteintech Group
Targeting: DIABLO
DFNA64, DIABLO-S, FLJ10537, FLJ25049, SMAC
Antibody data
- Antibody Data
- Antigen structure
- References [15]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
Reference
Comment
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- Product number
- 10434-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10434-1-AP, RRID:AB_2092647
- Product name
- DIABLO antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated DIABLO antibody (Cat. #10434-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references PCSK9 Promotes Hypoxia-Induced EC Pyroptosis by Regulating Smac Mitochondrion-Cytoplasm Translocation in Critical Limb Ischemia.
Glutathione Might Attenuate Arsenic-Induced Liver Injury by Modulating the Foxa2-XIAP Axis to Reduce Oxidative Stress and Mitochondrial Apoptosis.
Hydroxyl Group Acetylation of Quercetin Enhances Intracellular Absorption and Persistence to Upregulate Anticancer Activity in HepG2 Cells.
PKM2/PDK1 dual-targeted shikonin derivatives restore the sensitivity of EGFR-mutated NSCLC cells to gefitinib by remodeling glucose metabolism.
ROS-Triggered Self-Assembled Nanoparticles Based on a Chemo-Sonodynamic Combinational Therapy Strategy for the Noninvasive Elimination of Hypoxic Tumors.
Bag3 Regulates Mitochondrial Function and the Inflammasome Through Canonical and Noncanonical Pathways in the Heart.
Antioxidant Behavioural Phenotype in the Immp2l Gene Knock-Out Mouse.
The Photoperiod Regulates Granulosa Cell Apoptosis through the FSH-Nodal/ALK7 Signaling Pathway in Phodopus sungorus.
Botrychium schaffneri Underw. extract acts via DIABLO to induce apoptosis and inhibit proliferation of non-small cell lung carcinoma in vitro and in vivo.
Shikonin and 4-hydroxytamoxifen synergistically inhibit the proliferation of breast cancer cells through activating apoptosis signaling pathway in vitro and in vivo.
Mechanisms underlying the protective effect of tannic acid against arsenic trioxide‑induced cardiotoxicity in rats: Potential involvement of mitochondrial apoptosis.
Resveratrol Reduces Oxidative Stress and Apoptosis in Podocytes via Sir2-Related Enzymes, Sirtuins1 (SIRT1)/Peroxisome Proliferator-Activated Receptor γ Co-Activator 1α (PGC-1α) Axis.
Resveratrol ameliorates podocyte damage in diabetic mice via SIRT1/PGC-1α mediated attenuation of mitochondrial oxidative stress.
Phloretin induces apoptosis of human esophageal cancer via a mitochondria-dependent pathway.
Cathelicidin PR-39 peptide inhibits hypoxia/reperfusion-induced kidney cell apoptosis by suppression of the endoplasmic reticulum-stress pathway.
Zhang M, Chen Y, Qiu Y, Sun J, He J, Liu Z, Shi J, Wei W, Wu G, Liang J
JACC. Basic to translational science 2023 Sep;8(9):1060-1077
JACC. Basic to translational science 2023 Sep;8(9):1060-1077
Glutathione Might Attenuate Arsenic-Induced Liver Injury by Modulating the Foxa2-XIAP Axis to Reduce Oxidative Stress and Mitochondrial Apoptosis.
Zhang H, Jin B, Liu L, Li H, Zheng X, Li M, He R, Wang K
Biological trace element research 2023 Nov;201(11):5201-5212
Biological trace element research 2023 Nov;201(11):5201-5212
Hydroxyl Group Acetylation of Quercetin Enhances Intracellular Absorption and Persistence to Upregulate Anticancer Activity in HepG2 Cells.
Sakao K, Saruwatari H, Minami S, Hou DX
International journal of molecular sciences 2023 Nov 23;24(23)
International journal of molecular sciences 2023 Nov 23;24(23)
PKM2/PDK1 dual-targeted shikonin derivatives restore the sensitivity of EGFR-mutated NSCLC cells to gefitinib by remodeling glucose metabolism.
Lin H, Han H, Yang M, Wen Z, Chen Q, Ma Y, Wang X, Wang C, Yin T, Wang X, Lu G, Chen H, Qi J, Yang Y
European journal of medicinal chemistry 2023 Mar 5;249:115166
European journal of medicinal chemistry 2023 Mar 5;249:115166
ROS-Triggered Self-Assembled Nanoparticles Based on a Chemo-Sonodynamic Combinational Therapy Strategy for the Noninvasive Elimination of Hypoxic Tumors.
Li Y, Lin L, Xie J, Wei L, Xiong S, Yu K, Zhang B, Wang S, Li Z, Tang Y, Chen G, Li Z, Yu Z, Wang X
ACS applied materials & interfaces 2023 Mar 29;15(12):15893-15906
ACS applied materials & interfaces 2023 Mar 29;15(12):15893-15906
Bag3 Regulates Mitochondrial Function and the Inflammasome Through Canonical and Noncanonical Pathways in the Heart.
Wang J, Tomar D, Martin TG, Dubey S, Dubey PK, Song J, Landesberg G, McCormick MG, Myers VD, Merali S, Merali C, Lemster B, McTiernan CF, Khalili K, Madesh M, Cheung JY, Kirk JA, Feldman AM
JACC. Basic to translational science 2023 Jul;8(7):820-839
JACC. Basic to translational science 2023 Jul;8(7):820-839
Antioxidant Behavioural Phenotype in the Immp2l Gene Knock-Out Mouse.
Lawther AJ, Zieba J, Fang Z, Furlong TM, Conn I, Govindaraju H, Choong LLY, Turner N, Siddiqui KS, Bridge W, Merlin S, Hyams TC, Killingsworth M, Eapen V, Clarke RA, Walker AK
Genes 2023 Aug 28;14(9)
Genes 2023 Aug 28;14(9)
The Photoperiod Regulates Granulosa Cell Apoptosis through the FSH-Nodal/ALK7 Signaling Pathway in Phodopus sungorus.
Qi Y, Xue HL, Zheng YJ, Yin YF, Xu WL, Xu JH, Wu M, Chen L, Xu LX
Animals : an open access journal from MDPI 2022 Dec 16;12(24)
Animals : an open access journal from MDPI 2022 Dec 16;12(24)
Botrychium schaffneri Underw. extract acts via DIABLO to induce apoptosis and inhibit proliferation of non-small cell lung carcinoma in vitro and in vivo.
Liu YJ, Zhang YW, Zheng SL, Zheng XC, Ding HY, Xin WX, Sun J, Li L, Huang P
Annals of translational medicine 2021 Nov;9(22):1676
Annals of translational medicine 2021 Nov;9(22):1676
Shikonin and 4-hydroxytamoxifen synergistically inhibit the proliferation of breast cancer cells through activating apoptosis signaling pathway in vitro and in vivo.
Lin HY, Han HW, Wang YS, He DL, Sun WX, Feng L, Wen ZL, Yang MK, Lu GH, Wang XM, Qi JL, Yang YH
Chinese medicine 2020;15:23
Chinese medicine 2020;15:23
Mechanisms underlying the protective effect of tannic acid against arsenic trioxide‑induced cardiotoxicity in rats: Potential involvement of mitochondrial apoptosis.
Xue Y, Li M, Xue Y, Jin W, Han X, Zhang J, Chu X, Li Z, Chu L
Molecular medicine reports 2020 Dec;22(6):4663-4674
Molecular medicine reports 2020 Dec;22(6):4663-4674
Resveratrol Reduces Oxidative Stress and Apoptosis in Podocytes via Sir2-Related Enzymes, Sirtuins1 (SIRT1)/Peroxisome Proliferator-Activated Receptor γ Co-Activator 1α (PGC-1α) Axis.
Zhang T, Chi Y, Ren Y, Du C, Shi Y, Li Y
Medical science monitor : international medical journal of experimental and clinical research 2019 Feb 15;25:1220-1231
Medical science monitor : international medical journal of experimental and clinical research 2019 Feb 15;25:1220-1231
Resveratrol ameliorates podocyte damage in diabetic mice via SIRT1/PGC-1α mediated attenuation of mitochondrial oxidative stress.
Zhang T, Chi Y, Kang Y, Lu H, Niu H, Liu W, Li Y
Journal of cellular physiology 2019 Apr;234(4):5033-5043
Journal of cellular physiology 2019 Apr;234(4):5033-5043
Phloretin induces apoptosis of human esophageal cancer via a mitochondria-dependent pathway.
Duan H, Wang R, Yan X, Liu H, Zhang Y, Mu D, Han J, Li X
Oncology letters 2017 Dec;14(6):6763-6768
Oncology letters 2017 Dec;14(6):6763-6768
Cathelicidin PR-39 peptide inhibits hypoxia/reperfusion-induced kidney cell apoptosis by suppression of the endoplasmic reticulum-stress pathway.
Liu J, Xue W, Xiang H, Zheng J, Zhao Y, Jiao L, Jiao Z
Acta biochimica et biophysica Sinica 2016 Aug;48(8):714-22
Acta biochimica et biophysica Sinica 2016 Aug;48(8):714-22
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HepG2 cells were subjected to SDS PAGE followed by western blot with 10434-1-AP(DIABLO antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human testis using 10434-1-AP(DIABLO antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The DIABLO antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human DIABLO. This antibody recognizes human, mouse, rat antigen. The DIABLO antibody has been validated for the following applications: ELISA, WB, IHC analysis.