ABIN968785

antibody from antibodies-online

Targeting: DIABLO DFNA64, DIABLO-S, FLJ10537, FLJ25049, SMAC

Western blot (Data presented on provider website)

Antibody Data

Product number

ABIN968785

Provider

antibodies-online

Product name

anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) (AA 125-239), (pSer463), (pSer465), (pSer467) antibody

Antibody type

Monoclonal

Antigen

Human Smac/DIABLO aa. 125-239

Description

Purified from tissue culture supernatant or ascites by affinity chromatography.

Reactivity

Human

Host

Mouse

Epitope

AA 125-239,pSer463,pSer465,pSer467

Isotype

IgG

Antibody clone number

56

Vial size

50 μg

Concentration

250 μg/ml

Storage

-20°C

References

Submitted references

Therapeutic potential of 4-1BB (CD137) as a regulator for effector CD8(+) T cells.

Kim YJ, Broxmeyer HE
Journal of hematotherapy & stem cell research 2001 Aug;10(4):441-9

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Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition.

Du C, Fang M, Li Y, Li L, Wang X
Cell 2000 Jul 7;102(1):33-42

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Structural and biochemical basis of apoptotic activation by Smac/DIABLO.

Chai J, Du C, Wu JW, Kyin S, Wang X, Shi Y
Nature 2000 Aug 24;406(6798):855-62

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Evidence that hematopoietic stem cells express mouse c-kit but do not depend on steel factor for their generation.

Ikuta K, Weissman IL
Proceedings of the National Academy of Sciences of the United States of America 1992 Feb 15;89(4):1502-6