Tissue expression
Cell line expression
Protein structure
PTPA
Protein phosphatase 2 phosphatase activatorPPP2R4, PR53
Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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antibodies-online | ![]() |
2 references | Monoclonal |
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LSBio | ![]() |
Monoclonal |
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OriGene | ![]() |
Monoclonal |
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Acris Antibodies GmbH | ![]() |
Monoclonal |
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GeneTex | ![]() |
Monoclonal |
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