ABIN357836

antibody from antibodies-online

Targeting: PHB PHB1

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Antibody Data

Product number

ABIN357836

Provider

antibodies-online

Product name

anti-Prohibitin (PHB) (N-Term) antibody

Antibody type

Polyclonal

Antigen

This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human PHB1.

Description

Protein A Chromatography followed by peptide affinity purification.

Reactivity

Human

Host

Rabbit

Epitope

N-Term

Vial size

0.4 mL

Concentration

0.25 mg/mL

Storage

Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

Prohibitin silencing reverses stabilization of mitochondrial integrity and chemoresistance in ovarian cancer cells by increasing their sensitivity to apoptosis.

Gregory-Bass RC, Olatinwo M, Xu W, Matthews R, Stiles JK, Thomas K, Liu D, Tsang B, Thompson WE
International journal of cancer. Journal international du cancer 2008 May 1;122(9):1923-30

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The PHB1/2 phosphocomplex is required for mitochondrial homeostasis and survival of human T cells.

Ross JA, Nagy ZS, Kirken RA
The Journal of biological chemistry 2008 Feb 22;283(8):4699-713

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Assignment of the human prohibitin gene (PHB) to chromosome 17 and identification of a DNA polymorphism.

White JJ, Ledbetter DH, Eddy RL Jr, Shows TB, Stewart DA, Nuell MJ, Friedman V, Wood CM, Owens GA, McClung JK
Genomics 1991 Sep;11(1):228-30