orb533836

antibody from Biorbyt
Targeting: PHB PHB1
Provider product page for orb533836
Western blot
Immunohistochemistry

Antibody data

Product number
orb533836 - Provider product page
Provider
Biorbyt
Product name
Prohibitin Antibody / PHB
Antibody type
Monoclonal
Description
This antibody recognizes a protein of 30kDa which is identified as Prohibitin (PHB), an evolutionarily conserved protein with homologues found in yeast to man. It is located in the inner membrane of mitochondria. Although PHB mRNA and protein expression occurs throughout the cell cycle, maximum levels are detected during the G1/S phase transition and minimum levels are seen in S phase and the G2/mitosis boundary. Prohibitin is located exclusively in the mitochondria with the highest concentration on the inner membrane. It is an ideal mitochondrial marker. It shows anti-proliferative activity and has been proposed to play a role in normal cell cycle regulation, replicative senescence, cellular immortalization, and tumor suppression.
Reactivity
Human
Host
Mouse
Conjugate
Unconjugated
Antibody clone number
PHB/1881
Vial size
20 ug
Storage
Store the Prohibitin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
PHB protein structure - orb533836 shown in red.