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- Antigen structure
- References [11]
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- Western blot [1]
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- Product number
- 24280-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- MEFV antibody
- Antibody type
- Polyclonal
- Description
- MEFV antibody (Cat. #24280-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Tubuloside B Alleviates Aβ(25-35) Induced PC12 Cell Injury by Attenuating Pyroptosis, Apoptosis and Excessive Autophagy.
Dual-targeting nuclear and mitochondrial DNA damage drives immunogenic activation via PANoptosis for synergistic magneto-thermodynamic-chemotherapy.
Hydroxysafflor Yellow A Ameliorates Ischemic Stroke by Inhibiting NLRP3, AIM2, and Pyrin Inflammasome-Mediated Pyroptosis.
Investigation of PANoptosis pathway in age-related macular degeneration triggered by Aβ1-40.
Pre-electroacupuncture Ameliorates Cerebral Ischemia-reperfusion Injury by Inhibiting Microglial RhoA/pyrin/GSDMD Signaling Pathway.
Integrative Gut Microbiota and Metabolomic Analyses Reveal the PANoptosis- and Ferroptosis-Related Mechanisms of Chrysoeriol in Inhibiting Melanoma.
Lycopene Protects against Atrazine-Induced Kidney STING-Dependent PANoptosis through Stabilizing mtDNA via Interaction with Sam50/PHB1.
Inhibition of autophagy in microglia and macrophages exacerbates innate immune responses and worsens brain injury outcomes.
Transcriptional licensing is required for Pyrin inflammasome activation in human macrophages and bypassed by mutations causing familial Mediterranean fever.
FcγR-mediated SARS-CoV-2 infection of monocytes activates inflammation.
Function and mechanism of pyrin and IL-10 in the regulation of the inflammasome in pulmonary vascular endothelial cells following hemorrhagic shock.
Yang H, Fu R, Duan Y, Hua Y, Wei T, Li G, Gu X, Li M, Yu X, Li L, Cao L, Wang ZZ, Zhang C, Lv Y, He M, Xiao W
Neurotoxicity research 2026 Mar 19;44(2)
Neurotoxicity research 2026 Mar 19;44(2)
Dual-targeting nuclear and mitochondrial DNA damage drives immunogenic activation via PANoptosis for synergistic magneto-thermodynamic-chemotherapy.
Wu L, Su J, Cao Y, Yuan H, Li Z, Ren J, Xiao M, Yu K, Liang B
Biomaterials 2026 Jun;329:123924
Biomaterials 2026 Jun;329:123924
Hydroxysafflor Yellow A Ameliorates Ischemic Stroke by Inhibiting NLRP3, AIM2, and Pyrin Inflammasome-Mediated Pyroptosis.
Ding YL, Qiao LJ, Fang H, Fan LL, Wu D, Xu JP, Lv QH, Deng MZ, Qiu YH, Zhou ZY, Huang Y, Zheng JY, Zhang SJ, Cai YF
Neurochemical research 2025 Jun 13;50(3):201
Neurochemical research 2025 Jun 13;50(3):201
Investigation of PANoptosis pathway in age-related macular degeneration triggered by Aβ1-40.
He Y, Lu J, Du Y, Zhao L, Gong L, Wu P, Shu Q, Peng H, Wang X
Scientific reports 2025 Apr 19;15(1):13514
Scientific reports 2025 Apr 19;15(1):13514
Pre-electroacupuncture Ameliorates Cerebral Ischemia-reperfusion Injury by Inhibiting Microglial RhoA/pyrin/GSDMD Signaling Pathway.
Fang H, Fan LL, Ding YL, Wu D, Zheng JY, Cai YF, Huang Y, Qiao LJ, Zhang SJ, Zhan J
Neurochemical research 2024 Nov;49(11):3105-3117
Neurochemical research 2024 Nov;49(11):3105-3117
Integrative Gut Microbiota and Metabolomic Analyses Reveal the PANoptosis- and Ferroptosis-Related Mechanisms of Chrysoeriol in Inhibiting Melanoma.
Liu Y, Wang L, Huang T, Li Y, Zhang H
Journal of agricultural and food chemistry 2024 Nov 13;72(45):25173-25185
Journal of agricultural and food chemistry 2024 Nov 13;72(45):25173-25185
Lycopene Protects against Atrazine-Induced Kidney STING-Dependent PANoptosis through Stabilizing mtDNA via Interaction with Sam50/PHB1.
Yi BJ, Wang CC, Li XW, Xu YR, Ma XY, Jian PA, Talukder M, Li XN, Li JL
Journal of agricultural and food chemistry 2024 Jul 3;72(26):14956-14966
Journal of agricultural and food chemistry 2024 Jul 3;72(26):14956-14966
Inhibition of autophagy in microglia and macrophages exacerbates innate immune responses and worsens brain injury outcomes.
Hegdekar N, Sarkar C, Bustos S, Ritzel RM, Hanscom M, Ravishankar P, Philkana D, Wu J, Loane DJ, Lipinski MM
Autophagy 2023 Jul;19(7):2026-2044
Autophagy 2023 Jul;19(7):2026-2044
Transcriptional licensing is required for Pyrin inflammasome activation in human macrophages and bypassed by mutations causing familial Mediterranean fever.
Mangan MSJ, Gorki F, Krause K, Heinz A, Pankow A, Ebert T, Jahn D, Hiller K, Hornung V, Maurer M, Schmidt FI, Gerhard R, Latz E
PLoS biology 2022 Nov;20(11):e3001351
PLoS biology 2022 Nov;20(11):e3001351
FcγR-mediated SARS-CoV-2 infection of monocytes activates inflammation.
Junqueira C, Crespo Â, Ranjbar S, de Lacerda LB, Lewandrowski M, Ingber J, Parry B, Ravid S, Clark S, Schrimpf MR, Ho F, Beakes C, Margolin J, Russell N, Kays K, Boucau J, Das Adhikari U, Vora SM, Leger V, Gehrke L, Henderson LA, Janssen E, Kwon D, Sander C, Abraham J, Goldberg MB, Wu H, Mehta G, Bell S, Goldfeld AE, Filbin MR, Lieberman J
Nature 2022 Jun;606(7914):576-584
Nature 2022 Jun;606(7914):576-584
Function and mechanism of pyrin and IL-10 in the regulation of the inflammasome in pulmonary vascular endothelial cells following hemorrhagic shock.
Jin X, Yao Y, Lu X, Xu P, Xia Y, Zhu S
Experimental and therapeutic medicine 2019 Sep;18(3):1768-1774
Experimental and therapeutic medicine 2019 Sep;18(3):1768-1774
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The MEFV antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human MEFV. This antibody recognizes human antigen. The MEFV antibody has been validated for the following applications: ELISA, WB analysis.
