18204-1-AP

antibody from Proteintech Group

Targeting: PBX1

Provider product page for 18204-1-AP

Western blot

ELISA

Immunocytochemistry

Immunoprecipitation

Antibody data

Antibody Data
Antigen structure
References [18]
Comments [0]
Validations
Western blot [1]

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Product number: 18204-1-AP - Provider product page
Provider: Proteintech Group
Proper citation: Proteintech Cat#18204-1-AP, RRID:AB_10951860
Product name: PBX1 antibody
Antibody type: Polyclonal
Description: PBX1 antibody (Cat. #18204-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IP, WB,ELISA.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

PBX1 protein structure - 18204-1-AP shown in red.

Submitted references Overexpression of PBX1 attenuates oxidative stress and apoptosis in diabetic cardiomyopathy by transcriptionally inhibiting TXNIP.

Zhou R, Wang X, Li N
The international journal of biochemistry & cell biology 2025 Sep;186:106828

Lactate programs PBX1 lactylation and mesangial proliferation in lupus nephritis.

Liu E, Weng C, Yan C, Zhu X, Li X, Liu M, Wen Z, Liu Z
JCI insight 2025 Jun 9;10(11)

Protective effect of ginseng extract and total ginsenosides on hematopoietic stem cell damage by inhibiting cell apoptosis and regulating the intestinal microflora.

Liang Z, Gao X, Jing C, Yuan T, Zhang L, Yin Y, Ou J, Li X, Qi W, Zhao D, Su H, Zhang H
International journal of molecular medicine 2025 Jan;55(1)

Inhibition of the FEN1-PBX1 axis elicits cellular senescence in breast cancer via the increased intracellular reactive oxygen species levels.

Wu M, Wu B, Huang X, Wang Z, Zhu M, Zhu Y, Yu L, Liu J
Journal of translational medicine 2025 Feb 28;23(1):248

PBX1 attenuates inflammation and apoptosis of trophoblast cells induced by LPS through downregulating the transcription of TMUB1: PBX1 ameliorates RSA development.

Zhang X, Wang S, Liang L, Hu F, Zhang X, Cui X, Zhang Z, Wu X
Journal of molecular histology 2025 Feb 17;56(2):91

Loss of PBX1 function in Leydig cells causes testicular dysgenesis and male sterility.

Wang FC, Zhang XN, Wu SX, He Z, Zhang LY, Yang QE
Cellular and molecular life sciences : CMLS 2024 May 9;81(1):212

Hedgehog signaling is required for the maintenance of mesenchymal nephron progenitors.

Chung E, Deacon P, Hu YC, Lim HW, Park JS
bioRxiv : the preprint server for biology 2024 May 5;

Stromal thrombospondin 1 suppresses angiogenesis in oral submucous fibrosis.

Yang X, Zhao H, Li R, Chen Y, Xu Z, Shang Z
International journal of oral science 2024 Feb 26;16(1):17

M6A-methylated circPOLR2B forms an R-loop and regulates the biological behavior of glioma stem cells through positive feedback loops.

Lin H, Cui Z, E T, Xu H, Wang D, Wang P, Ruan X, Liu L, Xue Y
Cell death & disease 2024 Aug 1;15(8):554

High-quality single-cell transcriptomics from ovarian histological sections during folliculogenesis.

Ikeda H, Miyao S, Nagaoka S, Takashima T, Law SM, Yamamoto T, Kurimoto K
Life science alliance 2023 Nov;6(11)

Spindle function and Wnt pathway inhibition by PBX1 to suppress tumor progression via downregulating DCDC2 in colorectal cancer.

Dai W, Liu Y, Zhang T, Huang Z, Xu X, Zhao Z, Liu J, Zhai E, Cai S, Chen J
Oncogenesis 2023 Feb 4;12(1):3

A novel pathogenic variant c.262delA in PBX1 causing oligomeganephronia identified using whole-exome sequencing and a literature review.

Hu J, Yang H, Wang X, Ding J, Liao P, Zhu G, Qi C
American journal of medical genetics. Part A 2023 Dec;191(12):2850-2855

Caulis Polygoni Multiflori Accelerates Megakaryopoiesis and Thrombopoiesis via Activating PI3K/Akt and MEK/ERK Signaling Pathways.

Yang X, Wang L, Zeng J, Wu A, Qin M, Wen M, Zhang T, Chen W, Mei Q, Qin D, Yang J, Jiang Y, Wu J
Pharmaceuticals (Basel, Switzerland) 2022 Sep 28;15(10)

Integrated multi-omics approach revealed cellular senescence landscape.

Song Q, Hou Y, Zhang Y, Liu J, Wang Y, Fu J, Zhang C, Cao M, Cui Y, Zhang X, Wang X, Zhang J, Liu C, Zhang Y, Wang P
Nucleic acids research 2022 Oct 28;50(19):10947-10963

A Novel Antithrombocytopenia Agent, Rhizoma cibotii, Promotes Megakaryopoiesis and Thrombopoiesis through the PI3K/AKT, MEK/ERK, and JAK2/STAT3 Signaling Pathways.

Chen W, Zhu L, Wang L, Zeng J, Wen M, Xu X, Zou L, Huang F, Huang Q, Qin D, Mei Q, Yang J, Wang Q, Wu J
International journal of molecular sciences 2022 Nov 14;23(22)

Divergent transcriptional regulation of astrocyte reactivity across disorders.

Burda JE, O'Shea TM, Ao Y, Suresh KB, Wang S, Bernstein AM, Chandra A, Deverasetty S, Kawaguchi R, Kim JH, McCallum S, Rogers A, Wahane S, Sofroniew MV
Nature 2022 Jun;606(7914):557-564

Decreased levels of constitutive proteasomes in experimental autoimmune encephalomyelitis may be caused by a combination of subunit displacement and reduced Nfe2l1 expression.

Shanley KL, Hu CL, Bizzozero OA
Journal of neurochemistry 2020 Mar;152(5):585-601

Neuroprotective Action of Teriflunomide in a Mouse Model of Transient Middle Cerebral Artery Occlusion.

Lu Z, Zhang D, Cui K, Fu X, Man J, Lu H, Yu L, Gao Y, Liu X, Liao L, Li X, Liu C, Zhang Y, Zhang Z, Wang J
Neuroscience 2020 Jan 21;428:228-241

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: The PBX1 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human PBX1. This antibody recognizes human, mouse, rat antigen. The PBX1 antibody has been validated for the following applications: ELISA, WB analysis.
Appendix: 18204-1-AP.pdf

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