14226-1-AP
antibody from Proteintech Group
Targeting: S100A9
60B8AG, CAGB, CFAG, CGLB, LIAG, MAC387, MIF, MRP14, NIF, P14
Antibody data
- Antibody Data
- Antigen structure
- References [20]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
Reference
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- Product number
- 14226-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14226-1-AP, RRID:AB_2254232
- Product name
- S100A9 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated S100A9 antibody (Cat. #14226-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references The role of S100A8/A9 in the pathogenesis of acute exacerbations of pulmonary fibrosis.
Shengmai Yin Alleviates Particulate Matter-Aggravated Ischemic Damage by Inhibiting S100a9 Expression.
Integrated network pharmacology and bioinformatics analysis reveals MME as key target of Notoginsenoside R1 in diabetic nephropathy.
NAMPT Impairs Vascular Permeability in Periodontitis by Influencing FASN-mediated Lipogenesis.
Attenuative Effect of Grifola frondosa (Maitake Mushroom) on Severe DSS-Induced Colitis in Vitamin D-Deficient Mice.
Prunella vulgaris polyphenols alleviate liver injury-uveitis comorbidity by regulating acylcarnitine via the S100A9-PP2A-AMPK pathway.
Timosaponin AIII from Anemarrhena asphodeloides binds and inhibits S100A8-mediated neutrophil infiltration and NET formation ameliorates MASH.
Inflammation-Related Factors S100A9 and TLR2 in Cardiomyocyte Hypertrophy.
Erianin induces GSDMD-dependent pyroptosis and synergistically enhances doxorubicin efficacy via the PI3K/AKT signaling pathway in diffuse large B-cell lymphoma.
S100A9 as a promising therapeutic target for diabetic foot ulcers.
QDPR deficiency drives immune suppression in pancreatic cancer.
Lung dECM matrikine-based hydrogel reverses bleomycin-induced pulmonary fibrosis by suppressing M2 macrophage polarization.
Hyperactivation of β-catenin signal in hepatocellular carcinoma recruits myeloid-derived suppressor cells through PF4-CXCR3 axis.
S100 calcium-binding protein A9 promotes skin regeneration through toll-like receptor 4 during tissue expansion.
Downregulation of S100A9 Reverses Cisplatin-Resistance and Inhibits Proliferation and Migration in Hypopharyngeal Carcinoma.
Single-cell RNA Sequencing Uncovered the Involvement of an Endothelial Subset in Neutrophil Recruitment in Chemically Induced Rat Pulmonary Inflammation.
TRPM8 deficiency attenuates liver fibrosis through S100A9-HNF4α signaling.
S100 calcium-binding protein A9 from tumor-associated macrophage enhances cancer stem cell-like properties of hepatocellular carcinoma.
KRAS-IRF2 Axis Drives Immune Suppression and Immune Therapy Resistance in Colorectal Cancer.
Histopathological assessment of calcification and inflammation of calcific aortic valves from patients with and without diabetes mellitus.
Nakamura N, Higo H, Senoo S, Taniguchi A, Ozeki T, Sunami R, Inukai Y, Yamamoto S, Itano J, Tanaka A, Tomonobu N, Kinoshita R, Sakaguchi M, Maeda Y, Miyahara N
American journal of physiology. Lung cellular and molecular physiology 2026 May 1;330(5):L593-L609
American journal of physiology. Lung cellular and molecular physiology 2026 May 1;330(5):L593-L609
Shengmai Yin Alleviates Particulate Matter-Aggravated Ischemic Damage by Inhibiting S100a9 Expression.
Yang YM, Zhang Y, Li Y, Qu SQ, Deng SQ, Zheng ZY, Chen LN, Li YJ
Environmental toxicology 2026 Mar 21;
Environmental toxicology 2026 Mar 21;
Integrated network pharmacology and bioinformatics analysis reveals MME as key target of Notoginsenoside R1 in diabetic nephropathy.
Gan X, Liang M, Shadekejiang H, Hong H, Lu J, Li X, Zhang X, Lu C
BMC complementary medicine and therapies 2026 Feb 1;26(1)
BMC complementary medicine and therapies 2026 Feb 1;26(1)
NAMPT Impairs Vascular Permeability in Periodontitis by Influencing FASN-mediated Lipogenesis.
Xiao Y, Ma J, Li Z, Gou H, Chen X, Zhou Y, Shen M, Li L, Xu Y
International journal of biological sciences 2025;21(6):2707-2724
International journal of biological sciences 2025;21(6):2707-2724
Attenuative Effect of Grifola frondosa (Maitake Mushroom) on Severe DSS-Induced Colitis in Vitamin D-Deficient Mice.
Nishikawa M, Miyagi R, Kugimiya Y, Chudan S, Furusawa Y, Ikushiro S
Molecular nutrition & food research 2025 Oct;69(19):e70135
Molecular nutrition & food research 2025 Oct;69(19):e70135
Prunella vulgaris polyphenols alleviate liver injury-uveitis comorbidity by regulating acylcarnitine via the S100A9-PP2A-AMPK pathway.
Xie J, Xiong S, Yu J, Ma X, Xiang F, Chen Y, Xia B, Li Y, Zhang Z, Liao D, Lin L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156675
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156675
Timosaponin AIII from Anemarrhena asphodeloides binds and inhibits S100A8-mediated neutrophil infiltration and NET formation ameliorates MASH.
Bai Y, Ju J, Xie R, Li J, Zhao X, Fang X, Zhu M, Lan X, Luo H
International immunopharmacology 2025 Dec 3;166:115539
International immunopharmacology 2025 Dec 3;166:115539
Inflammation-Related Factors S100A9 and TLR2 in Cardiomyocyte Hypertrophy.
Jin KJ, Pan L, Huang CX, Yin C, Wang Y, Zhang J, Gong H
Current medical science 2025 Aug;45(4):819-830
Current medical science 2025 Aug;45(4):819-830
Erianin induces GSDMD-dependent pyroptosis and synergistically enhances doxorubicin efficacy via the PI3K/AKT signaling pathway in diffuse large B-cell lymphoma.
Mei H, Qiu M, Liu R, Song T, Gao Z, Zhang Q, Wang Y, Hao J, Gao M, Yang Z, Wang H
Chinese medical journal 2025 Aug 20;
Chinese medical journal 2025 Aug 20;
S100A9 as a promising therapeutic target for diabetic foot ulcers.
Wan R, Fang S, Zhang X, Zhou W, Bi X, Yuan L, Lv Q, Song Y, Tang W, Shi Y, Li T
Chinese medical journal 2025 Apr 20;138(8):973-981
Chinese medical journal 2025 Apr 20;138(8):973-981
QDPR deficiency drives immune suppression in pancreatic cancer.
Liu J, He X, Deng S, Zhao S, Zhang S, Chen Z, Xue C, Zeng L, Zhao H, Zhou Y, Bai R, Xu Z, Liu S, Zhou Q, Li M, Zhang J, Huang X, Chen R, Wang L, Lin D, Zheng J
Cell metabolism 2024 May 7;36(5):984-999.e8
Cell metabolism 2024 May 7;36(5):984-999.e8
Lung dECM matrikine-based hydrogel reverses bleomycin-induced pulmonary fibrosis by suppressing M2 macrophage polarization.
Zhu X, Yang Y, Mao S, Liu Q, Li Y, Yang Y, Gao M, Bao J, Li W, Li Y
Biofabrication 2024 Dec 27;17(1)
Biofabrication 2024 Dec 27;17(1)
Hyperactivation of β-catenin signal in hepatocellular carcinoma recruits myeloid-derived suppressor cells through PF4-CXCR3 axis.
Wang K, Wu J, Yang Z, Zheng B, Shen S, Wang RR, Zhang Y, Wang HY, Chen L, Qiu X
Cancer letters 2024 Apr 1;586:216690
Cancer letters 2024 Apr 1;586:216690
S100 calcium-binding protein A9 promotes skin regeneration through toll-like receptor 4 during tissue expansion.
Zhang Y, Song Y, Du J, Liu W, Dong C, Huang Z, Zhang Z, Yang L, Wang T, Xiong S, Dong L, Guo Y, Dang J, He Q, Yu Z, Ma X
Burns & trauma 2023;11:tkad030
Burns & trauma 2023;11:tkad030
Downregulation of S100A9 Reverses Cisplatin-Resistance and Inhibits Proliferation and Migration in Hypopharyngeal Carcinoma.
Zeng S, Tan G, Wang T, Wang X, Zhou Z, Xiao J, Li T, Zhang G, Li W
Journal of oncology 2022;2022:9341731
Journal of oncology 2022;2022:9341731
Single-cell RNA Sequencing Uncovered the Involvement of an Endothelial Subset in Neutrophil Recruitment in Chemically Induced Rat Pulmonary Inflammation.
Huang H, Yang Y, Song T, Yang Y, Zhu Y, Liu Z, Li L, Wang X
International journal of medical sciences 2022;19(4):669-680
International journal of medical sciences 2022;19(4):669-680
TRPM8 deficiency attenuates liver fibrosis through S100A9-HNF4α signaling.
Liu Q, Lei X, Cao Z, Zhang J, Yan L, Fu J, Tong Q, Qin W, Shao Y, Liu C, Liu Z, Wang Z, Chu Y, Xu G, Liu S, Wen X, Yamamoto H, Mori M, Liang XM, Xu X
Cell & bioscience 2022 May 7;12(1):58
Cell & bioscience 2022 May 7;12(1):58
S100 calcium-binding protein A9 from tumor-associated macrophage enhances cancer stem cell-like properties of hepatocellular carcinoma.
Wei R, Zhu WW, Yu GY, Wang X, Gao C, Zhou X, Lin ZF, Shao WQ, Wang SH, Lu M, Qin LX
International journal of cancer 2021 Mar 1;148(5):1233-1244
International journal of cancer 2021 Mar 1;148(5):1233-1244
KRAS-IRF2 Axis Drives Immune Suppression and Immune Therapy Resistance in Colorectal Cancer.
Liao W, Overman MJ, Boutin AT, Shang X, Zhao D, Dey P, Li J, Wang G, Lan Z, Li J, Tang M, Jiang S, Ma X, Chen P, Katkhuda R, Korphaisarn K, Chakravarti D, Chang A, Spring DJ, Chang Q, Zhang J, Maru DM, Maeda DY, Zebala JA, Kopetz S, Wang YA, DePinho RA
Cancer cell 2019 Apr 15;35(4):559-572.e7
Cancer cell 2019 Apr 15;35(4):559-572.e7
Histopathological assessment of calcification and inflammation of calcific aortic valves from patients with and without diabetes mellitus.
Mosch J, Gleissner CA, Body S, Aikawa E
Histology and histopathology 2017 Mar;32(3):293-306
Histology and histopathology 2017 Mar;32(3):293-306
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- human heart tissue were subjected to SDS PAGE followed by western blot with 14226-1-AP(S100A9 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Immunohistochemical of paraffin-embedded human breast cancer using 14226-1-AP(S100A9 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The S100A9 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human S100A9. This antibody recognizes human antigen. The S100A9 antibody has been validated for the following applications: ELISA, WB, IHC analysis.