26992-1-AP

antibody from Proteintech Group

Targeting: S100A9 60B8AG, CAGB, CFAG, CGLB, LIAG, MAC387, MIF, MRP14, NIF, P14

Provider product page for 26992-1-AP

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Antigen structure
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Product number: 26992-1-AP - Provider product page
Provider: Proteintech Group
Product name: S100A9 antibody
Antibody type: Polyclonal
Description: KD/KO validated S100A9 antibody (Cat. #26992-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
Reactivity: Human, Mouse
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

S100A9 protein structure - 26992-1-AP shown in red.

Submitted references Single-cell RNA sequencing reveals S100a9(hi) macrophages promote the transition from acute inflammation to fibrotic remodeling after myocardial ischemia‒reperfusion.

Shen S, Zhang M, Wang X, Liu Q, Su H, Sun B, Guo Z, Tian B, Gan H, Gong C, Ma L
Theranostics 2024;14(3):1241-1259

Overexpressing S100A9 ameliorates NK cell dysfunction in estrogen receptor-positive breast cancer.

Liu Y, Li M, Fang Z, Gao S, Cheng W, Duan Y, Wang X, Feng J, Yu T, Zhang J, Wang T, Hu A, Zhang H, Rong Z, Shakila SS, Shang Y, Kong F, Liu J, Li Y, Ma F
Cancer immunology, immunotherapy : CII 2024 May 7;73(7):117

S100A9(+)CD14(+) monocytes contribute to anti-PD-1 immunotherapy resistance in advanced hepatocellular carcinoma by attenuating T cell-mediated antitumor function.

Tu X, Chen L, Zheng Y, Mu C, Zhang Z, Wang F, Ren Y, Duan Y, Zhang H, Tong Z, Liu L, Sun X, Zhao P, Wang L, Feng X, Fang W, Liu X
Journal of experimental & clinical cancer research : CR 2024 Mar 8;43(1):72

Scleroglucan protects the intestine from irradiation-induced injury by targeting the IL-17 signaling pathway.

Huang D, Wang Y, Zhai X, Shen Q, Zhang L, Fang D, Fang L, Zhang J, Ma Y, Chu C, Liu G, Cheng Y, Liu C, Du J, Cai J
International immunopharmacology 2024 Mar 10;129:111614

Nebulized platelet-derived extracellular vesicles attenuate chronic cigarette smoke-induced murine emphysema.

Xuan W, Wang S, Alarcon-Calderon A, Bagwell MS, Para R, Wang F, Zhang C, Tian X, Stalboerger P, Peterson T, Sabbah MS, Du Z, Sarrafian T, Mahlberg R, Hillestad ML, Rizzo SA, Paradise CR, Behfar A, Vassallo R
Translational research : the journal of laboratory and clinical medicine 2024 Jul;269:76-93

A proteome-wide screen identifies the calcium binding proteins, S100A8/S100A9, as clinically relevant therapeutic targets in aortic dissection.

Jiang H, Zhao Y, Su M, Sun L, Chen M, Zhang Z, Ilyas I, Wang Z, Little PJ, Wang L, Weng J, Ge J, Xu S
Pharmacological research 2024 Jan;199:107029

Discovery of galectin-8 as an LILRB4 ligand driving M-MDSCs defines a class of antibodies to fight solid tumors.

Wang Y, Sun Y, Deng S, Liu J, Yu J, Chi H, Han X, Zhang Y, Shi J, Wang Y, Quan Y, Li H, Xu J
Cell reports. Medicine 2024 Jan 16;5(1):101374

Single-cell RNA profiling reveals classification and characteristics of mononuclear phagocytes in colorectal cancer.

Ji T, Fu H, Wang L, Chen J, Tian S, Wang G, Wang L, Wang Z
PLoS genetics 2024 Feb;20(2):e1011176

Whitening of brown adipose tissue inhibits osteogenic differentiation via secretion of S100A8/A9.

Wang T, Zhao C, Zhang J, Li S, Zhang Y, Gong Y, Zhou Y, Yan L, Zhang S, Zhang Z, Hu H, Liu A, Bai X, Zou Z
iScience 2024 Feb 16;27(2):108857

S100 calcium-binding protein A9 promotes skin regeneration through toll-like receptor 4 during tissue expansion.

Zhang Y, Song Y, Du J, Liu W, Dong C, Huang Z, Zhang Z, Yang L, Wang T, Xiong S, Dong L, Guo Y, Dang J, He Q, Yu Z, Ma X
Burns & trauma 2023;11:tkad030

S100a9 inhibits Atg9a transcription and participates in suppression of autophagy in cardiomyocytes induced by β(1)-adrenoceptor autoantibodies.

Zhi X, Shi S, Li Y, Ma M, Long Y, Li C, Hao H, Liu H, Wang X, Wang L
Cellular & molecular biology letters 2023 Sep 18;28(1):74

IL-17 promotes melanoma through TRAF2 as a scaffold protein recruiting PIAS2 and ELAVL1 to induce EPHA5.

Du J, Du Y, Chen L, Liu H
Biochimica et biophysica acta. Molecular cell research 2023 Oct;1870(7):119547

Targeting upregulation of the immunosuppressive activity of MDSCs with indirubin as a novel strategy to alleviate psoriasis.

Hou Y, Zhang H, Zhu Y, He X, Li W, Su L, Liu M, Chen X, Shen F, Chen X, Jiang W, Zou C, Xu Z
International immunopharmacology 2023 Oct;123:110710

Transcriptomics and metabolomics study in mouse kidney of the molecular mechanism underlying energy metabolism response to hypoxic stress in highland areas.

Gao Y, Long Q, Yang H, Hu Y, Xu Y, Tang C, Gu C, Yong S
Experimental and therapeutic medicine 2023 Nov;26(5):533

Senescent immune cells accumulation promotes brown adipose tissue dysfunction during aging.

Feng X, Wang L, Zhou R, Zhou R, Chen L, Peng H, Huang Y, Guo Q, Luo X, Zhou H
Nature communications 2023 Jun 2;14(1):3208

Hemin protects UVB-induced skin damage through inhibiting keratinocytes apoptosis and reducing neutrophil infiltration.

Bai F, Fan C, Lin X, Wang HY, Wu B, Feng CL, Zhou R, Wu YW, Tang W
Journal of photochemistry and photobiology. B, Biology 2023 Jan;238:112604

Identification of S100A9 as a Potential Inflammation-Related Biomarker for Radiation-Induced Lung Injury.

Liu Y, Wu M, Guo J, Tang Y, Jiang H, Yang B, Wu M, Huang J
Journal of clinical medicine 2023 Jan 17;12(3)

Oral Immunotherapy Reshapes Intestinal Immunosuppression via Metabolic Reprogramming to Enhance Systemic Anti-Tumor Immunity.

Cao X, Xu Y, Zhou C, Huo J, Su S, Liu L, Zhu Z, Li L, Jia W, Wang C, Zhen M
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Dec;10(35):e2302910

S100A8/A9 as a risk factor for breast cancer negatively regulated by DACH1.

Zhang X, Niu M, Li T, Wu Y, Gao J, Yi M, Wu K
Biomarker research 2023 Dec 13;11(1):106

Neutrophils regulate tumor angiogenesis in oral squamous cell carcinoma and the role of Chemerin.

Gao F, Feng Y, Hu X, Zhang X, Li T, Wang Y, Ge S, Wang C, Chi J, Tan X, Wang N
International immunopharmacology 2023 Aug;121:110540

Nuclear proinflammatory cytokine S100A9 enhances expression of human papillomavirus oncogenes via transcription factor TEAD1.

Mori S, Ishii Y, Takeuchi T, Kukimoto I
Journal of virology 2023 Aug 31;97(8):e0081523

Integrated MicroRNA and Secretome Analysis of Human Endometrial Organoids Reveal the miR-3194-5p/Aquaporin/S100A9 Module in Regulating Trophoblast Functions.

Dong Y, Li J, Cao D, Zhong J, Liu X, Duan YG, Lee KF, Yeung WSB, Lee CL, Chiu PCN
Molecular & cellular proteomics : MCP 2023 Apr;22(4):100526

Schwann Cells Accelerate Osteogenesis via the Mif/CD74/FOXO1 Signaling Pathway In Vitro.

Li JQ, Jiang HJ, Su XY, Feng L, Zhan NZ, Li SS, Chen ZJ, Chang BH, Cheng PZ, Yang L, Pei GX
Stem cells international 2022;2022:4363632

The Infiltration of Neutrophil Granulocytes Due to Loss of PTEN Was Associated with Poor Response to Immunotherapy in Renal Cell Carcinoma.

Wu F, Chen J, Yao K, Fan D, Wang M, Liu Y, Xin S, Sun Z, Li S, Sun Y, Liu Q
Journal of inflammation research 2022;15:6553-6567

Shuangxinfang Prevents S100A9-Induced Macrophage/Microglial Inflammation to Improve Cardiac Function and Depression-Like Behavior in Rats After Acute Myocardial Infarction.

Sun Y, Wang Z, Hou J, Shi J, Tang Z, Wang C, Zhao H
Frontiers in pharmacology 2022;13:832590

Hepatic RACK1 deficiency protects against fulminant hepatitis through myeloid-derived suppressor cells.

Liu G, Wang Q, Deng L, Huang X, Yang G, Cheng Q, Guo T, Guo L, Niu C, Yang X, Dong J, Zhang J
Theranostics 2022;12(5):2248-2265

The role of S100A9 in the interaction between pancreatic ductal adenocarcinoma cells and stromal cells.

Kung PJ, Lai TY, Cao J, Hsu LC, Chiang TC, Ou-Yang P, Tsai CY, Tsai YF, Lin CW, Chen CC, Tsai MK, Tien YW, Lee CY
Cancer immunology, immunotherapy : CII 2022 Mar;71(3):705-718

Comparison of viral RNA-host protein interactomes across pathogenic RNA viruses informs rapid antiviral drug discovery for SARS-CoV-2.

Zhang S, Huang W, Ren L, Ju X, Gong M, Rao J, Sun L, Li P, Ding Q, Wang J, Zhang QC
Cell research 2022 Jan;32(1):9-23

Bmal1 Regulates Macrophage Polarize Through Glycolytic Pathway in Alcoholic Liver Disease.

Zhou Y, Wu M, Xu L, Cheng J, Shen J, Yang T, Zhang L
Frontiers in pharmacology 2021;12:640521

Pancreatic ductal deletion of S100A9 alleviates acute pancreatitis by targeting VNN1-mediated ROS release to inhibit NLRP3 activation.

Xiang H, Guo F, Tao X, Zhou Q, Xia S, Deng D, Li L, Shang D
Theranostics 2021;11(9):4467-4482

Ovarian cancer modulates the immunosuppressive function of CD11b(+)Gr1(+) myeloid cells via glutamine metabolism.

Udumula MP, Sakr S, Dar S, Alvero AB, Ali-Fehmi R, Abdulfatah E, Li J, Jiang J, Tang A, Buekers T, Morris R, Munkarah A, Giri S, Rattan R
Molecular metabolism 2021 Nov;53:101272

Triptolide analog LLDT-8 ameliorates psoriasis-like dermatitis in BALB/c mice via suppressing the IL-36α signaling pathway.

Qi Q, Li Q, Zhu H, Lu H, Yang X, Wu Y, Feng C, Fan C, Li H, Wu B, Gao Y, Zhang Z, Zhou H, Zuo J, Tang W
Pharmacological research 2021 Jul;169:105678

MIN score predicts primary response to infliximab/adalimumab and vedolizumab therapy in patients with inflammatory bowel diseases.

Shi Y, He W, Zhong M, Yu M
Genomics 2021 Jul;113(4):1988-1998

Gut microbiota from patients with arteriosclerotic CSVD induces higher IL-17A production in neutrophils via activating RORγt.

Cai W, Chen X, Men X, Ruan H, Hu M, Liu S, Lu T, Liao J, Zhang B, Lu D, Huang Y, Fan P, Rao J, Lei C, Wang J, Ma X, Zhu Q, Li L, Zhu X, Hou Y, Li S, Dong Q, Tian Q, Ai L, Luo W, Zuo M, Shen L, Xie C, Song H, Xu G, Zheng K, Zhang Z, Lu Y, Qiu W, Chen T, Xiang AP, Lu Z
Science advances 2021 Jan;7(4)

Keratin 1 attenuates hypoxic pulmonary artery hypertension by suppressing pulmonary artery media smooth muscle expansion.

Zhang L, Zeng XX, Li YM, Chen SK, Tang LY, Wang N, Yang X, Lin MJ
Acta physiologica (Oxford, England) 2021 Feb;231(2):e13558

Psycho-cardiology therapeutic effects of Shuangxinfang in rats with depression-behavior post acute myocardial infarction: Focus on protein S100A9 from proteomics.

Sun Y, Wang Z, Wang C, Tang Z, Zhao H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Dec;144:112303

The "Matrisome" reveals the characterization of skin keloid microenvironment.

Zhang S, Liu B, Wang W, Lv L, Gao D, Chai M, Li M, Wu Z, Zhu Y, Ma J, Leng L
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Apr;35(4):e21237

Identification of lysine acetylome in cervical cancer by label-free quantitative proteomics.

Zhang L, Wang W, Zhang S, Wang Y, Guo W, Liu Y, Wang Y, Zhang Y
Cancer cell international 2020;20:182

Identification of differentially expressed proteins associated with recurrence in ovarian endometriotic cysts.

Zhu G, Kong J, Fu X, Liu F, Huang H, Hong L, Wang K
Systems biology in reproductive medicine 2020 Feb;66(1):59-69

Global Proteome and Phosphoproteome Characterization of Sepsis-induced Kidney Injury.

Lin YH, Platt MP, Fu H, Gui Y, Wang Y, Gonzalez-Juarbe N, Zhou D, Yu Y
Molecular & cellular proteomics : MCP 2020 Dec;19(12):2030-2047

Proteomic analysis of human periodontal ligament cells under hypoxia.

Li Q, Luo T, Lu W, Yi X, Zhao Z, Liu J
Proteome science 2019;17:3

Comparative proteomic profiling of human dental pulp stem cells and periodontal ligament stem cells under in vitro osteogenic induction.

Wang H, Ma D, Zhang X, Xu S, Ning T, Wu B
Archives of oral biology 2018 May;89:9-19

Quantitative proteomics analysis of differentially expressed proteins in ruptured and unruptured cerebral aneurysms by iTRAQ.

Jiang P, Wu J, Chen X, Ning B, Liu Q, Li Z, Li M, Yang F, Cao Y, Wang R, Wang S
Journal of proteomics 2018 Jun 30;182:45-52

Pancreatic cancer-derived exosomes promote tumor metastasis and liver pre-metastatic niche formation.

Yu Z, Zhao S, Ren L, Wang L, Chen Z, Hoffman RM, Zhou J
Oncotarget 2017 Sep 8;8(38):63461-63483

Proteomic analyses of Urine Exosomes reveal New Biomarkers of Diabetes in Pregnancy.

Ramachandrarao SP, Hamlin AA, Awdishu L, Overcash R, Zhou M, Proudfoot J, Ishaya M, Aghania E, Madrigal A, Kokoy-Mondragon C, Kao K, Khoshaba R, Bounkhoun A, Ghassemian M, Tarsa M, Naviaux RK
Madridge journal of diabetes 2016;1(1):11-22

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