350701

antibody from BioLegend

Targeting: S100A9 60B8AG, CAGB, CFAG, CGLB, LIAG, MAC387, MIF, MRP14, NIF, P14

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Flow cytometry (Data presented on provider website)

Antibody Data

Product number

350701

Provider

BioLegend

Proper citation

BioLegend Cat#350701, RRID:AB_10690687

Product name

Purified anti-human MRP-14 (S100A9)

Antibody type

Monoclonal

Antigen

Recombinant human MRP-14

Description

MRP-14, also known as S100A9, belongs to the S100 family of proteins containing 2-EF-hand calcium-binding motifs. It forms non-covalently associated complexes with another S100 family member, MRP-8. MRP14 is expressed in neutrophils and monocytes; it also has been found in ileal tissue eosinophils. The S100A8/A9 complex has been shown to play a role during calcium-dependent activation as well as have antibacterial, antifungal, immunomodulating, and anti-proliferative effects. It also functions as a chemoattractant factor for neutrophils and recently has been considered an endogenous activator of Toll-like receptor 4. A recent report has identified S100A9 as a marker for CD14(+) HLA-DR(-/low) MDSCs.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Vial size

25 µg

Concentration

0.5 mg/ml

Storage

The antibody solution should be stored undiluted at 4°C.