Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- BS3158 - Provider product page
- Provider
- Bioworld Technology, Inc
- Proper citation
- Bioworld Technology Cat#BS3158, RRID:AB_1662116
- Product name
- AR ÉÇ3 (L291) polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide, corresponding to amino acids 250-300 of Human AR-ÉÇ3.
- Description
- Beta 3-adrenergic receptors (b3-ARs) bind cathecholamines (epinephrine, norepinephrine), and primarily regulate lipolysis and thermogenesis in adipose. b3-ARs are present in adipose tissues, heart, and in smooth muscle of bladder, colon, small intestine, and stomach. The human corpus cavernosum exhibits basal b3-AR-mediated vasorelaxant tone and activity is linked to inhibition of the RhoA/Rho-kinase pathway. b3-AR interacts directly with the SH3 domain of Src through proline-rich motifs (PXXP) in the third intracellular loop and the carboxy-terminus.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- Western blot (WB) analysis of AR-¦Â3 (L291) pAb at 1:500 dilutionLane1:MCF-7 cell lysateLane2:Mouse kidney tissue lysateLane3:Rat liver tissue lysate