AFC-TAB-104

antibody from Creative Biolabs

Targeting: CD2 SRBC

ELISA (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunoprecipitation (Recommended by provider)

Flow cytometry (Recommended by provider)

Blocking/Neutralizing (Recommended by provider)

Functional assay (Recommended by provider)

Antibody Data

Product number

AFC-TAB-104

Provider

Creative Biolabs

Product name

Afuco? Anti-CD2 ADCC Recombinant Antibody (Siplizumab), ADCC Enhanced

Antibody type

Monoclonal

Description

This product is an ADCC enhanced antibody produced by our Afuco? platform. Recombinant monoclonal antibody to CD2. Siplizumab (MEDI-507) is a novel monoclonal antibody with a human IgG1, kappa directed to CD2. The agent has shown potent immunomodulatory effects, selectively suppressing the function of T and NK cells, and is currently being tested as a possible treatment for psoriasis and in the prevention of graft-versus-host disease.

Reactivity

Human

Host

Human

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

Siplizumab

Storage

Store at +4¡ãC short term (1-2 weeks). Aliquot and store at -20¡ãC long term. Avoid repeated freeze/thaw cycles.