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Flow cytometryAntibody data
- Antibody Data
- Antigen structure
- References [2]
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- Validations
- Flow cytometry [1]
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- Product number
- 300209 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#300209, RRID:AB_314033
- Product name
- PE/Cy5 anti-human CD2
- Antibody type
- Monoclonal
- Antigen
- CD2
- Description
- CD2 is a 50 kD type I transmembrane glycoprotein also known as LFA-2, T11, and sheep red blood cell receptor (SRBC-R). This immunoglobulin superfamily member is expressed on thymocytes, T lymphocytes, NK cells, and thymic B cell subsets. The major ligand for CD2 is CD58 (also known as LFA-3). CD2 has also been reported to bind CD48, CD59, and CD15. CD2 plays a critical role in alternative T cell activation, T cell signaling, and cell-cell adhesion.
- Reactivity
- Human, Porcine, Simian
- Host
- Mouse
- Conjugate
- Red dye
- Isotype
- IgG
- Vial size
- 25 tests
- Storage
- The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Submitted references Sustained signaling by canonical helper T cell cytokines throughout the reactive lymph node.
T follicular helper cells differentiate from Th2 cells in response to helminth antigens.
Perona-Wright G, Mohrs K, Mohrs M
Nature immunology 2010 Jun;11(6):520-6
Nature immunology 2010 Jun;11(6):520-6
T follicular helper cells differentiate from Th2 cells in response to helminth antigens.
Zaretsky AG, Taylor JJ, King IL, Marshall FA, Mohrs M, Pearce EJ
The Journal of experimental medicine 2009 May 11;206(5):991-9
The Journal of experimental medicine 2009 May 11;206(5):991-9
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- BioLegend (provider)
- Main image
- Experimental details
- Human peripheral blood lymphocytes stained with RPA-2.10 PE/Cy5
- Conjugate
- Yellow dye
