MAB1597

antibody from Novus Biologicals

Targeting: FCGR3B CD16, CD16b, FCG3, FCGR3

Western blot (Data presented on provider website)

Flow cytometry (Data presented on provider website)

Antibody Data

Product number

MAB1597

Provider

Novus Biologicals

Product name

Mouse Monoclonal Fc gamma RIIIB/CD16b Antibody

Antibody type

Monoclonal

Description

Protein A or G purified from hybridoma culture supernatant. Detects human Fc gamma RIIIB/CD16b in direct ELISAs and Western blots. In Western blots, no cross-reactivity with recombinant human Fc gamma RIIA or recombinant mouse Fc gamma RIII is observed. In flow cytometry of whole blood, recognition of Fc gamma RIIIB on the granulocyte population, but not Fc gamma RIIIA on NK cells, is observed.

Reactivity

Human

Host

Mouse

Isotype

IgG

Vial size

500 ug

Concentration

LYOPH

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.

References

Submitted references

VISTA deficiency attenuates antibody-induced arthritis and alters macrophage gene expression in response to simulated immune complexes.

Ceeraz S, Eszterhas SK, Sergent PA, Armstrong DA, Ashare A, Broughton T, Wang L, Pechenick D, Burns CM, Noelle RJ, Vincenti MP, Fava RA
Arthritis research & therapy 2017 Dec 8;19(1):270

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α-1 Antitrypsin regulates human neutrophil chemotaxis induced by soluble immune complexes and IL-8.

Bergin DA, Reeves EP, Meleady P, Henry M, McElvaney OJ, Carroll TP, Condron C, Chotirmall SH, Clynes M, O'Neill SJ, McElvaney NG
The Journal of clinical investigation 2010 Dec;120(12):4236-50