Ab175611

antibody from Aladdin Scientific
Targeting: ITGA4 CD49D
Provider product page for Ab175611
No application information provided.

Antibody data

Product number
Ab175611 - Provider product page
Provider
Aladdin Scientific
Product name
Natalizumab (anti-ITGA4)
Antibody type
Recombinant
Description
Natalizumab (anti-ITGA4) is a recombinant, humanized IgG4 monoclonal antibody, binds to _4_1-integrin and blocks its interaction with vascular cell adhesion molecule-1 (VCAM-1). Natalizumab (anti-ITGA4) can be used for the treatment of relapsing remitting multiple sclerosis and Crohn's disease. Natalizumab (anti-ITGA4) is also the first targeted therapy which blocks an essential mechanism for lymphocyte entry to the CNS and thus prevents acute demyelinating relapses.Purity>95% (SDS-PAGE&SEC)Endotoxin Level< 1.0EU/mg
Reactivity
Human
Conjugate
Unconjugated
Vial size
100_g,10mg,1mg,5mg
Concentration
Lot by Lot
Storage
Store at -80_ for 24 months. Upon delivery aliquot. Avoid freeze/thaw cycle.
ITGA4 protein structure - Ab175611 shown in red.