HPA003413

antibody from Atlas Antibodies

Targeting: MSL2 FLJ10546, KIAA1585, msl-2, MSL2L1, RNF184

Western blot (Data presented on provider website)

Antibody Data

Product number

HPA003413

Provider

Atlas Antibodies

Proper citation

Atlas Antibodies Cat#HPA003413, RRID:AB_1848659

Product name

Anti-MSL2

Antibody type

Polyclonal

Description

Polyclonal Antibody against Human MSL2, Gene description: male-specific lethal 2 homolog (Drosophila), Alternative Gene Names: FLJ10546, KIAA1585, msl-2, MSL2L1, RNF184, Validated applications: WB, Uniprot ID: Q9HCI7, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Concentration

0.3 mg/ml

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Handling

The antibody solution should be gently mixed before use.

References

Submitted references

MSL2 variants lead to a neurodevelopmental syndrome with lack of coordination, epilepsy, specific dysmorphisms, and a distinct episignature.

Karayol R, Borroto MC, Haghshenas S, Namasivayam A, Reilly J, Levy MA, Relator R, Kerkhof J, McConkey H, Shvedunova M, Petersen AK, Magnussen K, Zweier C, Vasileiou G, Reis A, Savatt JM, Mulligan MR, Bicknell LS, Poke G, Abu-El-Haija A, Duis J, Hannig V, Srivastava S, Barkoudah E, Hauser NS, van den Born M, Hamiel U, Henig N, Baris Feldman H, McKee S, Krapels IPC, Lei Y, Todorova A, Yordanova R, Atemin S, Rogac M, McConnell V, Chassevent A, Barañano KW, Shashi V, Sullivan JA, Peron A, Iascone M, Canevini MP, Friedman J, Reyes IA, Kierstein J, Shen JJ, Ahmed FN, Mao X, Almoguera B, Blanco-Kelly F, Platzer K, Treu AB, Quilichini J, Bourgois A, Chatron N, Januel L, Rougeot C, Carere DA, Monaghan KG, Rousseau J, Myers KA, Sadikovic B, Akhtar A, Campeau PM
American journal of human genetics 2024 Jul 11;111(7):1330-1351

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Shift in MSL1 alternative polyadenylation in response to DNA damage protects cancer cells from chemotherapeutic agent-induced apoptosis

Kunisky A, Anyaeche V, Herron R, Park C, Hwang H
Cell Reports 2021;37(2):109815

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Facultative dosage compensation of developmental genes on autosomes in Drosophila and mouse embryonic stem cells

Valsecchi C, Basilicata M, Semplicio G, Georgiev P, Gutierrez N, Akhtar A
Nature Communications 2018;9(1)

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DHX9 suppresses RNA processing defects originating from the Alu invasion of the human genome

Aktaş T, Avşar Ilık İ, Maticzka D, Bhardwaj V, Pessoa Rodrigues C, Mittler G, Manke T, Backofen R, Akhtar A
Nature 2017;544(7648):115-119

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Functional interplay between MSL1 and CDK7 controls RNA polymerase II Ser5 phosphorylation

Chlamydas S, Holz H, Samata M, Chelmicki T, Georgiev P, Pelechano V, Dündar F, Dasmeh P, Mittler G, Cadete F, Ramírez F, Conrad T, Wei W, Raja S, Manke T, Luscombe N, Steinmetz L, Akhtar A
Nature Structural & Molecular Biology 2016;23(6):580-589

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MOF-associated complexes ensure stem cell identity and Xist repression

Chelmicki T, Dündar F, Turley M, Khanam T, Aktas T, Ramírez F, Gendrel A, Wright P, Videm P, Backofen R, Heard E, Manke T, Akhtar A
eLife 2014;3