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- Antigen structure
- References [9]
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- Validations
- Western blot [1]
- Flow cytometry [1]
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- Product number
- 22146-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- Integrin alpha-1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated Integrin alpha-1 antibody (Cat. #22146-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: FC, IHC, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references DIREN mitigates DSS-induced colitis in mice and attenuates collagen deposition via inhibiting the Wnt/β-catenin and focal adhesion pathways.
NEIL1 drives the initiation of colorectal cancer through transcriptional regulation of COL17A1.
Downregulation of METTL6 mitigates cell progression, migration, invasion and adhesion in hepatocellular carcinoma by inhibiting cell adhesion molecules.
A combination index and glycoproteomics-based approach revealed synergistic anticancer effects of curcuminoids of turmeric against prostate cancer PC3 cells.
Integrin α1 promotes tumorigenicity and progressive capacity of colorectal cancer.
Exosome-derived ENO1 regulates integrin α6β4 expression and promotes hepatocellular carcinoma growth and metastasis.
FAM83A exerts tumor‑suppressive roles in cervical cancer by regulating integrins.
Integrin endocytosis on elastic substrates mediates mechanosensing.
17β-Estradiol Protects Rat Annulus Fibrosus Cells Against Apoptosis via α1 Integrin-Mediated Adhesion to Type I Collagen: An In-vitro Study.
Lai W, Wang Y, Huang C, Xu H, Zheng X, Li K, Wang J, Lou Z
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jun;175:116671
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jun;175:116671
NEIL1 drives the initiation of colorectal cancer through transcriptional regulation of COL17A1.
Cao JH, Cao CH, Lin JL, Li SY, He LJ, Han K, Chen JW, Li S, Wang X, Xie D, Wang FW
Cell reports 2024 Jan 23;43(1):113654
Cell reports 2024 Jan 23;43(1):113654
Downregulation of METTL6 mitigates cell progression, migration, invasion and adhesion in hepatocellular carcinoma by inhibiting cell adhesion molecules.
Bolatkan A, Asada K, Kaneko S, Suvarna K, Ikawa N, Machino H, Komatsu M, Shiina S, Hamamoto R
International journal of oncology 2022 Jan;60(1)
International journal of oncology 2022 Jan;60(1)
A combination index and glycoproteomics-based approach revealed synergistic anticancer effects of curcuminoids of turmeric against prostate cancer PC3 cells.
Wei MM, Zhao SJ, Dong XM, Wang YJ, Fang C, Wu P, Song GQ, Gao JN, Huang ZH, Xie T, Zhou JL
Journal of ethnopharmacology 2021 Mar 1;267:113467
Journal of ethnopharmacology 2021 Mar 1;267:113467
Integrin α1 promotes tumorigenicity and progressive capacity of colorectal cancer.
Li H, Wang Y, Rong SK, Li L, Chen T, Fan YY, Wang YF, Yang CR, Yang C, Cho WC, Yang J
International journal of biological sciences 2020;16(5):815-826
International journal of biological sciences 2020;16(5):815-826
Exosome-derived ENO1 regulates integrin α6β4 expression and promotes hepatocellular carcinoma growth and metastasis.
Jiang K, Dong C, Yin Z, Li R, Mao J, Wang C, Zhang J, Gao Z, Liang R, Wang Q, Wang L
Cell death & disease 2020 Nov 12;11(11):972
Cell death & disease 2020 Nov 12;11(11):972
FAM83A exerts tumor‑suppressive roles in cervical cancer by regulating integrins.
Xu J, Lu W
International journal of oncology 2020 Aug;57(2):509-521
International journal of oncology 2020 Aug;57(2):509-521
Integrin endocytosis on elastic substrates mediates mechanosensing.
Li J, Chen H, Xu Y, Hu J, Xie FQ, Yang C
Journal of biomechanics 2016 Sep 6;49(13):2644-2654
Journal of biomechanics 2016 Sep 6;49(13):2644-2654
17β-Estradiol Protects Rat Annulus Fibrosus Cells Against Apoptosis via α1 Integrin-Mediated Adhesion to Type I Collagen: An In-vitro Study.
Zhao CM, Chen Q, Zhang WJ, Huang AB, Zhang W, Yang HL, Zhang ZM
Medical science monitor : international medical journal of experimental and clinical research 2016 Apr 24;22:1375-83
Medical science monitor : international medical journal of experimental and clinical research 2016 Apr 24;22:1375-83
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HepG2 cells were subjected to SDS PAGE followed by western blot with 22146-1-AP(ITGA1 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Integrin alpha-1 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human Integrin alpha-1. This antibody recognizes human antigen. The Integrin alpha-1 antibody has been validated for the following applications: ELISA, WB, IHC, FC analysis.
