DCABH-2191

antibody from Creative Diagnostics

Targeting: ITGAE CD103, HUMINAE

No application information provided.

Antibody Data

Product number

DCABH-2191

Provider

Creative Diagnostics

Proper citation

Creative Diagnostics Cat#DCABH-2191, RRID:AB_2476108

Product name

Rabbit Anti-Human ITGAE monoclonal antibody, clone TO73-17

Antibody type

Monoclonal

Description

Integrins are heterodimers composed of noncovalently associated transmembrane a and b subunits. The 16 a and 8 b subunits heterodimerize to produce more than 20 different receptors. Most integrin receptors bind ligands that are components of the extracellular matrix, including Fibronectin, Collagen and Vitronectin. Certain integrins can also bind to soluble ligands such as Fibrinogen, or to counterreceptors on adjacent cells such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Ligands serve to cross-link or cluster integrins by binding to adjacent integrin receptors