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- Product number
- ABIN954296 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Phosphatidylinositol-3,4,5-Trisphosphate-Dependent Rac Exchange Factor 1 (PREX1) (AA 573-602), (Middle Region) antibody
- Antibody type
- Polyclonal
- Description
- Affinity chromatography on Protein A
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- AA 573-602, Middle Region
- Vial size
- 0.4 mL
- Storage
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Phosphatidylinositol 3,4,5-triphosphate-dependent Rac exchanger 1 (P-Rex-1), a guanine nucleotide exchange factor for Rac, mediates angiogenic responses to stromal cell-derived factor-1/chemokine stromal cell derived factor-1 (SDF-1/CXCL-12) linked to Rac activation, endothelial cell migration, and in vitro angiogenesis.
Mutation of ARHGAP9 in patients with coronary spastic angina.
Sphingosine-1-phosphate receptor S1P1 is regulated by direct interactions with P-Rex1, a Rac guanine nucleotide exchange factor.
Upregulation of PIP3-dependent Rac exchanger 1 (P-Rex1) promotes prostate cancer metastasis.
P-Rex1 - a multidomain protein that regulates neurite differentiation.
Carretero-Ortega J, Walsh CT, Hernández-García R, Reyes-Cruz G, Brown JH, Vázquez-Prado J
Molecular pharmacology 2010 Mar;77(3):435-42
Molecular pharmacology 2010 Mar;77(3):435-42
Mutation of ARHGAP9 in patients with coronary spastic angina.
Takefuji M, Asano H, Mori K, Amano M, Kato K, Watanabe T, Morita Y, Katsumi A, Itoh T, Takenawa T, Hirashiki A, Izawa H, Nagata K, Hirayama H, Takatsu F, Naoe T, Yokota M, Kaibuchi K
Journal of human genetics 2010 Jan;55(1):42-9
Journal of human genetics 2010 Jan;55(1):42-9
Sphingosine-1-phosphate receptor S1P1 is regulated by direct interactions with P-Rex1, a Rac guanine nucleotide exchange factor.
Ledezma-Sánchez BA, García-Regalado A, Guzmán-Hernández ML, Vázquez-Prado J
Biochemical and biophysical research communications 2010 Jan 22;391(4):1647-52
Biochemical and biophysical research communications 2010 Jan 22;391(4):1647-52
Upregulation of PIP3-dependent Rac exchanger 1 (P-Rex1) promotes prostate cancer metastasis.
Qin J, Xie Y, Wang B, Hoshino M, Wolff DW, Zhao J, Scofield MA, Dowd FJ, Lin MF, Tu Y
Oncogene 2009 Apr 23;28(16):1853-63
Oncogene 2009 Apr 23;28(16):1853-63
P-Rex1 - a multidomain protein that regulates neurite differentiation.
Waters JE, Astle MV, Ooms LM, Balamatsias D, Gurung R, Mitchell CA
Journal of cell science 2008 Sep 1;121(Pt 17):2892-903
Journal of cell science 2008 Sep 1;121(Pt 17):2892-903
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