60325-1-Ig

antibody from Proteintech Group

Targeting: FGFR1 BFGFR, CD331, CEK, FLG, FLT2, H2, H3, H4, H5, KAL2, N-SAM

Provider product page for 60325-1-Ig

Western blot

ELISA

Immunohistochemistry

Flow cytometry

Antibody data

Antibody Data
Antigen structure
References [33]
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Validations
Western blot [1]

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Product number: 60325-1-Ig - Provider product page
Provider: Proteintech Group
Product name: FGFR1 antibody
Antibody type: Monoclonal
Description: FGFR1 antibody (Cat. #60325-1-Ig) is a mouse monoclonal antibody that shows reactivity with human and has been validated for the following applications: FC, IHC, WB,ELISA.
Reactivity: Human
Host: Mouse
Conjugate: Unconjugated
Isotype: IgG
Antibody clone number: 10F12E7
Vial size: 20ul, 150ul

FGFR1 protein structure - 60325-1-Ig shown in red.

Submitted references Hydrogel Loaded with Peptide-Containing Nanocomplexes: Symphonic Cooperation of Photothermal Antimicrobial Nanoparticles and Prohealing Peptides for the Treatment of Infected Wounds.

Jia Q, Fu Z, Li Y, Kang Z, Wu Y, Ru Z, Peng Y, Huang Y, Luo Y, Li W, Hu Y, Sun X, Wang J, Deng Z, Wu C, Wang Y, Yang X
ACS applied materials & interfaces 2024 Mar 20;16(11):13422-13438

HnRNPA2B1 ISGylation Regulates m6A-Tagged mRNA Selective Export via ALYREF/NXF1 Complex to Foster Breast Cancer Development.

Jin T, Yang L, Chang C, Luo H, Wang R, Gan Y, Sun Y, Guo Y, Tang R, Chen S, Meng D, Dai P, Liu M
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jun;11(24):e2307639

ALKBH5 is a prognostic factor and promotes the angiogenesis of glioblastoma.

Fan Y, Yan D, Ma L, Liu X, Luo G, Hu Y, Kou X
Scientific reports 2024 Jan 14;14(1):1303

PKM2/Hif-1α signal suppression involved in therapeutics of pulmonary fibrosis with microcystin-RR but not with pirfenidone.

Ren Y, Wang J, Guo WW, Chen JW, Xu LZ, Wu ZW, Wang YP
Toxicon : official journal of the International Society on Toxinology 2024 Aug 28;247:107822

Fibroblast growth factor receptors 1 and 4 combined with lymph node metastasis predicts poor prognosis in oral cancer.

Gu ZY, Zhou R, Hong D, Han Y, Wang LZ, Li J, Zhang ZY, Shi CJ
Oral diseases 2024 Apr;30(3):1004-1017

Role of liver FGF21-KLB signaling in ketogenic diet-induced amelioration of hepatic steatosis.

Guo W, Cao H, Shen Y, Li W, Wang W, Cheng L, Cai M, Xu F
Nutrition & diabetes 2024 Apr 12;14(1):18

BIBF1120 Protects against Diabetic Retinopathy through Neovascularization-Related Molecules and the MAPK Signaling Pathway.

Cao X, Li T, Tian Y, Tian Y, Gao C, Zhang D, Song Y
Journal of ophthalmology 2023;2023:7355039

Paricalcitol improved cardiac hypertrophy and fibrosis through upregulation of fibroblast growth factor-23 and downregulation of transforming growth factor-beta in a rat model of isoproterenol-induced cardiomyopathy.

Wu CJ, Li YH, Chen HH
The Chinese journal of physiology 2023 Sep-Oct;66(5):306-312

A novel intronic circular RNA circFGFR1(int2) up-regulates FGFR1 by recruiting transcriptional activators P65/FUS and suppressing miR-4687-5p to promote prostate cancer progression.

Wang R, Zhong J, Pan X, Su Z, Xu Y, Zhang M, Chen X, Chen N, Yu T, Zhou Q
Journal of translational medicine 2023 Nov 22;21(1):840

Intracellular FGF1 promotes invasion and migration in thyroid carcinoma via HMGA1 independent of FGF receptors.

Chen Z, Zhong X, Tang W, Xia M, Liu C, Guo Y, Yi Y, Jiang Q, Zu X, Zhong J
Endocrine connections 2023 May 1;12(5)

The UCMSC-bFGF/Scaffold System Accelerates the Healing of the Uterine Full-Thickness Injury.

Wang L, Yao S, Huang F, Lv H, Liu D, Gao T, Wang B, Zhou Z, Cao C, Zhu Q, Weng Q, Zhao G, Hu Y
Tissue engineering. Part A 2023 Feb;29(3-4):112-125

Derazantinib Inhibits the Bioactivity of Keloid Fibroblasts via FGFR Signaling.

Xu S, Zhu Y, Wang P, Qi S, Shu B
Biomedicines 2023 Dec 5;11(12)

Effects of Infrared Combined with Methylcobalamin on the Vibratory Sensory Threshold and Nerve Conduction Velocity of the Lower Extremity in Patients with Diabetic Foot Treatment.

Wang Y, Lin S, Chen Z, Chen Q, Fu M
Disease markers 2022;2022:8287192

DJ-1/FGFR-1 Signaling Pathway Contributes to Sorafenib Resistance in Hepatocellular Carcinoma.

Chen X, Yang G, Guo X, Zhang J, Sun W, Liu D, Wang H, Liu S
Oxidative medicine and cellular longevity 2022;2022:2543220

Bevacizumab is an Efficient Therapeutic Approach with Low Side Effects in Patient-Derived Xenografts of Adenoid Cystic Carcinoma of the Lacrimal Gland.

Zhang J, Yan X, Liu R, Wu S, Liu Q, Li J, Ma J
Cancer management and research 2022;14:1023-1032

Blockade of phosphotyrosine pathways suggesting SH2 superbinder as a novel therapy for pulmonary fibrosis.

Wang M, Liu AD, Niu Q, Feng X, Zheng YY, Chen SJ, Xu H, Li Q, Hou GQ, Bi XY, Lu YZ, Cheng PP, Liang LM, Jiang YH, Zhao LQ, Liu F, Song LJ, Zhou LL, Xiao LY, Chen F, Li SS, Ma WL, Cao X, Ye H
Theranostics 2022;12(10):4513-4535

LncRNA SNHG1 Promotes the Progression of Pancreatic Cancer by Regulating FGFR1 Expression via Competitively Binding to miR-497.

Chen S, Guo W, Meng M, Wu D, Zhou T, Wang L, Xu J
Frontiers in oncology 2022;12:813850

Fibroblast Growth Factor 21 Protects Against Atrial Remodeling via Reducing Oxidative Stress.

Chen M, Zhong J, Wang Z, Xu H, Chen H, Sun X, Lu Y, Chen L, Xie X, Zheng L
Frontiers in cardiovascular medicine 2021;8:720581

The FGFR Family Inhibitor AZD4547 Exerts an Antitumor Effect in Ovarian Cancer Cells.

Na YR, Kim JY, Song CH, Kim M, Do YT, Vo TTL, Choi E, Ha E, Seo JH, Shin SJ
International journal of molecular sciences 2021 Oct 6;22(19)

Fisetin attenuates periodontitis through FGFR1/TLR4/NLRP3 inflammasome pathway.

Huang X, Shen H, Liu Y, Qiu S, Guo Y
International immunopharmacology 2021 Jun;95:107505

Upregulated insulin receptor tyrosine kinase substrate promotes the proliferation of colorectal cancer cells via the bFGF/AKT signaling pathway.

Wang S, Liu Z, Ma YM, Guan X, Jiang Z, Sun P, Liu ER, Zhang YK, Wang HY, Wang XS
Gastroenterology report 2021 Apr;9(2):166-175

Double layer composite membrane for preventing tendon adhesion and promoting tendon healing.

Yan Z, Meng X, Su Y, Chen Y, Zhang L, Xiao J
Materials science & engineering. C, Materials for biological applications 2021 Apr;123:111941

Human-like collagen promotes the healing of acetic acid-induced gastric ulcers in rats by regulating NOS and growth factors.

Xing M, Fu R, Liu Y, Wang P, Ma P, Zhu C, Fan D
Food & function 2020 May 1;11(5):4123-4137

LncRNA AGAP2-AS1 augments cell viability and mobility, and confers gemcitabine resistance by inhibiting miR-497 in colorectal cancer.

Hong S, Yan Z, Song Y, Bi M, Li S
Aging 2020 Mar 23;12(6):5183-5194

Interactome analysis reveals that lncRNA HULC promotes aerobic glycolysis through LDHA and PKM2.

Wang C, Li Y, Yan S, Wang H, Shao X, Xiao M, Yang B, Qin G, Kong R, Chen R, Zhang N
Nature communications 2020 Jun 22;11(1):3162

Brivanib, a multitargeted small-molecule tyrosine kinase inhibitor, suppresses laser-induced CNV in a mouse model of neovascular AMD.

Li L, Zhu M, Wu W, Qin B, Gu J, Tu Y, Chen J, Liu D, Shi Y, Liu X, Sang A, Ding D
Journal of cellular physiology 2020 Feb;235(2):1259-1273

Synergistic protection of tetramethylpyrazine phosphate and borneol on brain microvascular endothelium cells injured by hypoxia.

Yu B, Zhong FM, Yao Y, Deng SQ, Xu HQ, Lu JF, Ruan M, Shen XC
American journal of translational research 2019;11(4):2168-2180

Toxicity Effects of Methylene Blue on Rat Intervertebral Disc Annulus Fibrosus Cells.

Zhang L, Liu Y, Huang Z, Nan L, Wang F, Zhou S, Wang J, Feng X
Pain physician 2019 Mar;22(2):155-164

Dl-3-N-butylphthalide promotes angiogenesis and upregulates sonic hedgehog expression after cerebral ischemia in rats.

Zhou PT, Wang LP, Qu MJ, Shen H, Zheng HR, Deng LD, Ma YY, Wang YY, Wang YT, Tang YH, Tian HL, Zhang ZJ, Yang GY
CNS neuroscience & therapeutics 2019 Jun;25(6):748-758

Long non-coding RNA PVT1 promotes malignancy in human endometrial carcinoma cells through negative regulation of miR-195-5p.

Kong F, Ma J, Yang H, Yang D, Wang C, Ma X
Biochimica et biophysica acta. Molecular cell research 2018 Jul 19;

The expression and function of miR-424 in infantile skin hemangioma and its mechanism.

Yang L, Dai J, Li F, Cheng H, Yan D, Ruan Q
Scientific reports 2017 Sep 19;7(1):11846

Spiroplasma eriocheiris induces mouse 3T6-Swiss albino cell apoptosis that associated with the infection mechanism.

Hou L, Gu W, Zhu H, Yao W, Wang W, Meng Q
Molecular immunology 2017 Nov;91:75-85

Alpaca fiber growth is mediated by microRNA let-7b via down-regulation of target gene FGF5.

Wang T, Zhang Y, Wang HD, Shen Y, Liu N, Cao J, Yu XJ, Dong CS, He XY
Genetics and molecular research : GMR 2015 Oct 29;14(4):13754-63

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: The FGFR1 antibody from Proteintech is a mouse monoclonal antibody to a recombinant protein of human FGFR1. This antibody recognizes human, mouse antigen. The FGFR1 antibody has been validated for the following applications: ELISA, WB analysis.
Appendix: 60325-1-Ig.pdf

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