55138-1-AP

antibody from Proteintech Group

Targeting: PRKG2 cGKII, PKG2, PRKGR2

Western blot (Supportive data in Antibodypedia)

ELISA (Data presented on provider website)

Immunocytochemistry (Supportive data in Antibodypedia)

Immunoprecipitation (Data presented on provider website)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

55138-1-AP

Provider

Proteintech Group

Proper citation

Proteintech Cat#55138-1-AP, RRID:AB_10804353

Product name

PRKG2 antibody

Antibody type

Polyclonal

Description

KD/KO validated PRKG2 antibody (Cat. #55138-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

EDNRB inhibits the growth and migration of prostate cancer cells by activating the cGMP-PKG pathway.

Li X, Liu B, Wang S, Dong Q, Li J
Open medicine (Warsaw, Poland) 2024;19(1):20230875

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Erianin Exerts Antineoplastic Effects on Esophageal Squamous Cell Carcinoma Cells by Activating the cGMP-PKG Signaling Pathway.

Deng X, Wu Q, Li D, Liu Y
Nutrition and cancer 2023;75(6):1473-1484

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Sambucus williamsii Hance maintains bone homeostasis in hyperglycemia-induced osteopenia by reversing oxidative stress via cGMP/PKG signal transduction.

Shen YW, Cheng YA, Li Y, Li Z, Yang BY, Li X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Feb;110:154607

---

Maintaining hypoxia environment of subchondral bone alleviates osteoarthritis progression.

Zhang H, Wang L, Cui J, Wang S, Han Y, Shao H, Wang C, Hu Y, Li X, Zhou Q, Guo J, Zhuang X, Sheng S, Zhang T, Zhou D, Chen J, Wang F, Gao Q, Jing Y, Chen X, Su J
Science advances 2023 Apr 5;9(14):eabo7868

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High-Risk HPV16 E6 Activates the cGMP/PKG Pathway Through Glycosyltransferase ST6GAL1 in Cervical Cancer Cells.

Wang J, Liu G, Liu M, Cai Q, Yao C, Chen H, Song N, Yuan C, Tan D, Hu Y, Xiang Y, Xiang T
Frontiers in oncology 2021;11:716246

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The novel ZEB1-upregulated protein PRTG induced by Helicobacter pylori infection promotes gastric carcinogenesis through the cGMP/PKG signaling pathway.

Xiang T, Yuan C, Guo X, Wang H, Cai Q, Xiang Y, Luo W, Liu G
Cell death & disease 2021 Feb 4;12(2):150

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Phosphorylation of myelin regulatory factor by PRKG2 mediates demyelination in Huntington's disease.

Yin P, Liu Q, Pan Y, Yang W, Yang S, Wei W, Chen X, Hong Y, Bai D, Li XJ, Li S
EMBO reports 2020 Jun 4;21(6):e49783

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Linaclotide activates guanylate cyclase-C/cGMP/protein kinase-II-dependent trafficking of CFTR in the intestine.

Ahsan MK, Tchernychev B, Kessler MM, Solinga RM, Arthur D, Linde CI, Silos-Santiago I, Hannig G, Ameen NA
Physiological reports 2017 Jun;5(11)

Western blot

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

mouse brain tissue were subjected to SDS PAGE followed by western blot with 55138-1-AP(PRKG2 antibody) at dilution of 1:500

Sample type

tissue

Immunocytochemistry

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

The PRKG2 antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human PRKG2. This antibody recognizes human,mouse,rat antigen. The PRKG2 antibody has been validated for the following applications: ELISA, WB, IHC, IF analysis.

Appendix

55138-1-AP.pdf

Show more

Immunohistochemistry

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunohistochemical of paraffin-embedded human colon using 55138-1-AP(PRKG2 antibody) at dilution of 1:50 (under 10x lens)

Sample type

tissue

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunohistochemical of paraffin-embedded human colon using 55138-1-AP(PRKG2 antibody) at dilution of 1:50 (under 40x lens)

Sample type

tissue