16368-1-AP

antibody from Proteintech Group

Targeting: FZR1 CDC20C, CDH1, FZR, FZR2, HCDH, HCDH1, KIAA1242

Provider product page for 16368-1-AP

Western blot

ELISA

Immunocytochemistry

Immunoprecipitation

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [17]
Comments [0]
Validations
Western blot [2]

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Product number: 16368-1-AP - Provider product page
Provider: Proteintech Group
Proper citation: Proteintech Cat#16368-1-AP, RRID:AB_2107380
Product name: FZR1/Cdh1 antibody
Antibody type: Polyclonal
Description: FZR1/Cdh1 antibody (Cat. #16368-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

FZR1 protein structure - 16368-1-AP shown in red.

Submitted references Semaglutide ameliorates aortic endothelial cell dysfunction in sarcopenia through the SIRT1/cGAS-STING signaling axis.

Liu Y, Sun W, Huang Z, Qiao G, Tang L, Huang T, Wang X, Li L, Zhang X, Ye X, Yang P, Wu H
Free radical biology & medicine 2026 Jul;250:352-369

Selective autophagic degradation of glycolytic activator PFKFB3 contributes to maintaining intestinal epithelial barrier in inflammatory bowel disease.

Pan Y, Yang F, Wang L, Yang T, Du G, Xu C, Yang H, Yu M, Xiao W
International journal of molecular medicine 2026 Feb;57(2)

Phase separation of ERCC6L2-CtIP regulates the extent of DNA end resection.

Yin Y, Lin J, Cai X, Nie R, Lin J, Li S, Xiang Z, Ling Y, Zhang Y, Zhou J, Chen J, Lin W, Duan J, Zheng X, Xie D, Cai M
Nature cell biology 2025 Oct;27(10):1771-1784

Molecular recording of cellular protein kinase activity with chemical labeling.

Sun DE, Ng SW, Zheng Y, Xie S, Schwan N, Breuer P, Hoffmann DC, Michel J, Azorin DD, Boonekamp KE, Winkler F, Wick W, Boutros M, Li Y, Johnsson K
Nature chemical biology 2025 Nov;21(11):1818-1827

CDC20-Mediated Selective Autophagy Degradation of PBRM1 Affects Immunotherapy for Renal Cell Carcinoma.

Fan Y, Dan W, Que T, Wei Y, Liu B, Wang Z, Zhang Y, Wang Y, Liu T, Zhuang Y, Li M, Guo C, Zeng J, Ma B, Li L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(5):e2412967

CDH1 Orchestrates Anabolic Events to Promote Cell Cycle Initiation.

Mao YZ, Zhang JJ, You MQ, Wang H, Lin Y, Fang Y, Zhang HL, Qu YY, Zhou Q, Wang M, Li G, Guo ZF, Xu M, Liu J, Lin PC, Yuan YY, Kang Y, Zhao SM, Xu W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(47):e07584

IGFBP7 regulates cell proliferation and migration through JAK/STAT pathway in gastric cancer and is regulated by DNA and RNA methylation.

Mo W, Deng L, Cheng Y, Ge S, Wang J
Journal of cellular and molecular medicine 2024 Oct;28(19):e70080

ANGPTL4 mediated mesothelial-mesenchymal transition in pulmonary fibrosis: a potential therapeutic target.

Xia Y, Zhou F, Hui H, Dai L, Ouyang S
Journal of translational medicine 2024 Dec 20;22(1):1114

Phosphorylation determines the glucose metabolism reprogramming and tumor-promoting activity of sine oculis homeobox 1.

Lin Y, Li L, Yuan B, Luo F, Zhang X, Yang Y, Luo S, Lin J, Ye T, Zhang Y, Gao S, Ye Q
Signal transduction and targeted therapy 2024 Dec 2;9(1):337

E3 ubiquitin ligase APC/C(Cdh1) regulates SLC35F2 protein turnover and inhibits cancer progression in HeLa cells.

Colaco JC, Chandrasekaran AP, Karapurkar JK, Gowda DAA, Birappa G, Rajkumar S, Suresh B, Ko N, Hong SH, Oh SJ, Kim KS, Ramakrishna S
Biochimica et biophysica acta. General subjects 2023 Nov;1867(11):130454

DNA replication initiation factor RECQ4 possesses a role in antagonizing DNA replication initiation.

Xu X, Chang CW, Li M, Omabe K, Le N, Chen YH, Liang F, Liu Y
Nature communications 2023 Mar 4;14(1):1233

Loss of RanGAP1 drives chromosome instability and rapid tumorigenesis of osteosarcoma.

Gong Y, Zou S, Deng D, Wang L, Hu H, Qiu Z, Wei T, Yang P, Zhou J, Zhang Y, Zhu W, Xie X, Liao Z, Yang J, Zhang S, Liu A, Jiang Y, Zou Z, Bai X
Developmental cell 2023 Feb 6;58(3):192-210.e11

Bergenin, a PPARγ agonist, inhibits Th17 differentiation and subsequent neutrophilic asthma by preventing GLS1-dependent glutaminolysis.

Yang L, Zheng Y, Miao YM, Yan WX, Geng YZ, Dai Y, Wei ZF
Acta pharmacologica Sinica 2022 Apr;43(4):963-976

The cohesin stabilizer Sororin drives G(2)-M transition and spindle assembly in mammalian oocytes.

Zhou C, Zhang X, Miao Y, Zhang Y, Li Y, Xiong B
Science advances 2021 Sep 24;7(39):eabg9335

Cdh1-APC Regulates Protein Synthesis and Stress Granules in Neurons through an FMRP-Dependent Mechanism.

Valdez-Sinon AN, Lai A, Shi L, Lancaster CL, Gokhale A, Faundez V, Bassell GJ
iScience 2020 May 22;23(5):101132

A Cdh1-FoxM1-Apc axis controls muscle development and regeneration.

Chen Z, Li L, Xu S, Liu Z, Zhou C, Li Z, Liu Y, Wu W, Huang Y, Kuang M, Fan S, Li H, Li X, Song G, Wu WS, Chen J, Hou Y
Cell death & disease 2020 Mar 9;11(3):180

ERBB2 deficiency alters an E2F-1-dependent adaptive stress response and leads to cardiac dysfunction.

Perry MC, Dufour CR, Eichner LJ, Tsang DW, Deblois G, Muller WJ, Giguère V
Molecular and cellular biology 2014 Dec 1;34(23):4232-43

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: C6 cells were subjected to SDS PAGE followed by western blot with 16368-1-AP( FZR1 Antibody) at dilution of 1:600
Sample type: cell line

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: mouse heart tissue were subjected to SDS PAGE followed by western blot with 16368-1-AP( FZR1 Antibody) at dilution of 1:600
Sample type: tissue