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- Antigen structure
- References [275]
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- Product number
- 23274-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- PINK1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated PINK1 antibody (Cat. #23274-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Apolipoprotein A-1 Accelerated Liver Regeneration Through Regulating Autophagy Via AMPK-ULK1 Pathway.
NAD-Dependent Protein Deacetylase Sirtuin-1 Mediated Mitophagy Regulates Early Brain Injury After Subarachnoid Hemorrhage.
Involvement of autophagy in mesaconitine-induced neurotoxicity in HT22 cells revealed through integrated transcriptomic, proteomic, and m6A epitranscriptomic profiling.
Sestrin2 remedies neuroinflammatory response by inhibiting A1 astrocyte conversion via autophagy.
Human neural stem cells promote mitochondrial genesis to alleviate neuronal damage in MPTP-induced cynomolgus monkey models.
BMAL1 alleviates myocardial damage in sepsis by activating SIRT1 signaling and promoting mitochondrial autophagy.
Exploring the neuroprotective role of artesunate in mouse models of anti-NMDAR encephalitis: insights from molecular mechanisms and transmission electron microscopy.
Collagen I protects human keratinocytes HaCaT against UVB injury via restoring PINK1/parkin-mediated mitophagy.
L-Citrulline Ameliorates Iron Metabolism and Mitochondrial Quality Control via Activating AMPK Pathway in Intestine and Improves Microbiota in Mice with Iron Overload.
Alpha-ketoglutaric acid attenuates oxidative stress and modulates mitochondrial dynamics and autophagy of spleen in a piglet model of lipopolysaccharide-induced sepsis.
The opposite role of lactate dehydrogenase a (LDHA) in cervical cancer under energy stress conditions.
Propionate promotes ferroptosis and apoptosis through mitophagy and ACSL4-mediated ferroptosis elicits anti-leukemia immunity.
Ubiquitinome Analysis Uncovers Alterations in Synaptic Proteins and Glucose Metabolism Enzymes in the Hippocampi of Adolescent Mice Following Cold Exposure.
The HRI branch of the integrated stress response selectively triggers mitophagy.
Loss of FoxO1 activates an alternate mechanism of mitochondrial quality control for healthy adipose browning.
The mitochondrial UPR induced by ATF5 attenuates intervertebral disc degeneration via cooperating with mitophagy.
TBBPS caused necroptosis and inflammation in hepatocytes by blocking PINK1-PARKIN-mediated mitochondrial autophagy.
Atox1 protects hippocampal neurons after traumatic brain injury via DJ-1 mediated anti-oxidative stress and mitophagy.
Urolithin A improves Alzheimer's disease cognition and restores mitophagy and lysosomal functions.
Modulating synovial macrophage pyroptosis and mitophagy interactions to mitigate osteoarthritis progression using functionalized nanoparticles.
The regulation of MFG-E8 on the mitophagy in diabetic sarcopenia via the HSPA1L-Parkin pathway and the effect of D-pinitol.
Thiosemicarbazone Mixed-Valence Cu(I/II) Complex against Lung Adenocarcinoma Cells through Multiple Pathways Involving Cuproptosis.
HO-1 upregulation promotes mitophagy-dependent ferroptosis in PM2.5-exposed hippocampal neurons.
Adenylate kinase 4 promotes neuronal energy metabolism and mitophagy in early cerebral ischemia via Parkin/PKM2 pathway.
Mechanism Research of DHEA Treatment Improving Diminished Ovarian Reserve by Attenuating the AMPK-SIRT1 Signaling and Mitophagy.
Mitochondria-targeted ruthenium complexes can be generated in vitro and in living cells to target triple-negative breast cancer cells by autophagy inhibition.
THSG alleviates cerebral ischemia/reperfusion injury via the GluN2B-CaMKII-ERK1/2 pathway.
Drp1 regulated PINK1-dependent mitophagy protected duck follicular granulosa cells from acute heat stress injury.
Suppression of NLRP3 inflammasome activation by astragaloside IV via promotion of mitophagy to ameliorate radiation-induced renal injury in mice.
Melatonin protects against myocardial ischemia-reperfusion injury by inhibiting excessive mitophagy through the Apelin/SIRT3 signaling axis.
Activation of mitophagy improves cognitive dysfunction in diabetic mice with recurrent non-severe hypoglycemia.
Fluorochloridone induces mitochondrial dysfunction and apoptosis in primary goat Sertoli cells.
ErZhiTianGui Decoction alleviates age-related ovarian aging by regulating mitochondrial homeostasis and inhibiting ferroptosis.
Modeling drug-induced mitochondrial toxicity with human primary cardiomyocytes.
Control of NAD(+) homeostasis by autophagic flux modulates mitochondrial and cardiac function.
Blockade of angiotensin II modulates insulin-like growth factor 1-mediated skeletal muscle homeostasis in experimental steatohepatitis.
Cholesterol-induced HRD1 reduction accelerates vascular smooth muscle cell senescence via stimulation of endoplasmic reticulum stress-induced reactive oxygen species.
Gonococcal OMV-delivered PorB induces epithelial cell mitophagy.
Circ-CIMIRC inhibition alleviates CIH-induced myocardial damage via FbxL4-mediated ubiquitination of PINK1.
O-GlcNAcylation orchestrates porcine oocyte maturation through maintaining mitochondrial dynamics and function.
Geniposide effectively safeguards HT22 cells against Aβ-induced damage by activating mitophagy via the PINK1/Parkin signaling pathway.
Zinc ions regulate mitochondrial quality control in neurons under oxidative stress and reduce PANoptosis in spinal cord injury models via the Lgals3-Bax pathway.
SS-31 inhibits mtDNA-cGAS-STING signaling to improve POCD by activating mitophagy in aged mice.
VDR regulates mitochondrial function as a protective mechanism against renal tubular cell injury in diabetic rats.
Rapamycin can alleviate the submandibular gland pathology of Sjögren's syndrome by limiting the activation of cGAS-STING signaling pathway.
SIRT3 alleviates painful diabetic neuropathy by mediating the FoxO3a-PINK1-Parkin signaling pathway to activate mitophagy.
Characterization and function of PTEN-induced putative kinase 1 (PINK1) in process of Zinc alleviates hepatic lipid deposition of yellow catfish (Pelteobagrus fulvidraco).
Resveratrol Inhibits Zinc Deficiency-Induced Mitophagy and Exerts Cardiac Cytoprotective Effects.
The NLRX1-SLC39A7 complex orchestrates mitochondrial dynamics and mitophagy to rejuvenate intervertebral disc by modulating mitochondrial Zn(2+) trafficking.
Chaihu Shugan Powder inhibits interstitial cells of cajal mitophagy through USP30 in the treatment of functional dyspepsia.
Targeting PARP14 with lomitapide suppresses drug resistance through the activation of DRP1-induced mitophagy in multiple myeloma.
Iridium(III)-Based PD-L1 Agonist Regulates p62 and ATF3 for Enhanced Cancer Immunotherapy.
A mitochondrial surveillance mechanism activated by SRSF2 mutations in hematologic malignancies.
Tetrandrine alleviates pulmonary fibrosis by inhibiting alveolar epithelial cell senescence through PINK1/Parkin-mediated mitophagy.
Low-dose deoxynivalenol exposure inhibits hepatic mitophagy and hesperidin reverses this phenomenon by activating SIRT1.
TDCPP and TiO(2) NPs aggregates synergistically induce SH-SY5Y cell neurotoxicity by excessive mitochondrial fission and mitophagy inhibition.
Mitophagy activation by rapamycin enhances mitochondrial function and cognition in 5×FAD mice.
Icaritin with autophagy/mitophagy inhibitors synergistically enhances anticancer efficacy and apoptotic effects through PINK1/Parkin-mediated mitophagy in hepatocellular carcinoma.
Corn peptides attenuate non-alcoholic fatty liver disease via PINK1/Parkin-mediated mitochondrial autophagy.
Dexmedetomidine Ameliorates Cardiac Ischemia/Reperfusion Injury by Enhancing Autophagy Through Activation of the AMPK/SIRT3 Pathway.
Electroacupuncture Exerts Chondroprotective Effect in Knee Osteoarthritis of Rabbits Through the Mitophagy Pathway.
Exercise prevents fatal stress-induced myocardial injury in obese mice.
Exercise intervention improves mitochondrial quality in non-alcoholic fatty liver disease zebrafish.
Buyang Huanwu Decoction alleviates cerebral ischemic injury through modulating caveolin-1-mediated mitochondrial quality control.
Role of Pink1-mediated mitophagy in adenomyosis.
Knockdown of Y-box binding protein 1 induces autophagy in early porcine embryos.
SNAP25 ameliorates postoperative cognitive dysfunction by facilitating PINK1-dependent mitophagy and impeding caspase-3/GSDME-dependent pyroptosis.
SIRT3 regulates mitophagy in liver fibrosis through deacetylation of PINK1/NIPSNAP1.
Hypoxia-induced GPCPD1 depalmitoylation triggers mitophagy via regulating PRKN-mediated ubiquitination of VDAC1.
Aerobic exercise enhances mitochondrial homeostasis to counteract D-galactose-induced sarcopenia in zebrafish.
Mitophagy contributes to zinc-induced ferroptosis in porcine testis cells.
AP39 inhibits ferroptosis by inhibiting mitochondrial autophagy through the PINK1/parkin pathway to improve myocardial fibrosis with myocardial infarction.
Loss and recovery of myocardial mitochondria in mice under different tail suspension time: Apoptosis and mitochondrial fission, fusion and autophagy.
MDM2 upregulation induces mitophagy deficiency via Mic60 ubiquitination in fetal microglial inflammation and consequently neuronal DNA damage caused by exposure to ZnO-NPs during pregnancy.
Long-Term Exposure to Microcystin-LR Induces Gastric Toxicity by Activating the Mitogen-Activated Protein Kinase Signaling Pathway.
Co-exposure to environmentally relevant concentrations of cadmium and polystyrene nanoplastics induced oxidative stress, ferroptosis and excessive mitophagy in mice kidney.
Mitoquinone alleviates osteoarthritis progress by activating the NRF2-Parkin axis.
The lysosome-mitochondrion crosstalk engaged in silver nanoparticles-disturbed mitochondrial homeostasis.
PTP1B knockdown alleviates BMSCs senescence via activating AMPK-mediated mitophagy and promotes osteogenesis in senile osteoporosis.
3-MCPD Induced Mitochondrial Damage of Renal Cells Via the Rhythmic Protein BMAL1 Targeting SIRT3/SOD2.
Low expression of PINK1 and PARK2 predicts poor prognosis in patients with esophageal squamous cell carcinoma.
N-acetylcysteine attenuates the incidence of phlebitis induced by carbomer/vinorelbine gel.
Grape seed proanthocyanidins regulate mitophagy of endothelial cells and promote wound healing in mice through p-JNK/FOXO3a/ROS signal pathway.
PINK1-mediated mitophagy reduced inflammatory responses to Porphyromonas gingivalis in macrophages.
Acid ground nano-realgar processed product inhibits breast cancer by inducing mitophagy via the p53/BNIP3/NIX pathway.
Miquelianin in Folium Nelumbinis extract promotes white-to-beige fat conversion via blocking AMPK/DRP1/mitophagy and modulating gut microbiota in HFD-fed mice.
Melatonin exerts a protective effect in ameliorating nephrolithiasis via targeting AMPK/PINK1-Parkin mediated mitophagy and inhibiting ferroptosis in vivo and in vitro.
FGD5-AS1/miR-5590-3p/PINK1 induces Lenvatinib resistance in hepatocellular carcinoma.
Sulforaphane ameliorated podocyte injury according to regulation of the Nrf2/PINK1 pathway for mitophagy in diabetic kidney disease.
Liver metabolomics reveals potential mechanism of Jieduan-Niwan formula against acute-on-chronic liver failure (ACLF) by improving mitochondrial damage and TCA cycle.
Extracellular vesicle-derived silk fibroin nanoparticles loaded with MFGE8 accelerate skin ulcer healing by targeting the vascular endothelial cells.
ACO2 deficiency increases vulnerability to Parkinson's disease via dysregulating mitochondrial function and histone acetylation-mediated transcription of autophagy genes.
Shenlian extract decreases mitochondrial autophagy to regulate mitochondrial function in microvascular to alleviate coronary artery no-reflow.
Wei-Tong-Xin ameliorated cisplatin-induced mitophagy and apoptosis in gastric antral mucosa by activating the Nrf2/HO-1 pathway.
Metrnl Alleviates Lipid Accumulation by Modulating Mitochondrial Homeostasis in Diabetic Nephropathy.
NSC228155 alleviates septic cardiomyopathy via protecting mitochondria and inhibiting inflammation.
HC067047 as a potent TRPV4 inhibitor repairs endotoxemia colonic injury.
MCU Upregulation Overactivates Mitophagy by Promoting VDAC1 Dimerization and Ubiquitination in the Hepatotoxicity of Cadmium.
Berberine Rescues D-Ribose-Induced Alzheimer's Pathology via Promoting Mitophagy.
MFN1 augmentation prevents retinal degeneration in a Charcot-Marie-Tooth type 2A mouse model.
Impaired mitophagy causes mitochondrial DNA leakage and STING activation in ultraviolet B-irradiated human keratinocytes HaCaT.
Zinc deficiency compromises the maturational competence of porcine oocyte by inducing mitophagy and apoptosis.
The physiological metabolite α-ketoglutarate ameliorates osteoarthritis by regulating mitophagy and oxidative stress.
Naringin regulates endoplasmic reticulum stress and mitophagy through the ATF3/PINK1 signaling axis to alleviate pulmonary fibrosis.
MAGL regulates synovial macrophage polarization vis inhibition of mitophagy in osteoarthritic pain.
Neuro death through autophagy via the acetylation of FoxO1 by SIRT2 in the hippocampus of mice in a autism spectrum disorder mice model.
DBP induced autophagy and necrotic apoptosis in HepG2 cells via the mitochondrial damage pathway.
A copper complex that combats triple negative breast cancer by restraining angiogenesis.
Overexpression of fatty acid synthase attenuates bleomycin induced lung fibrosis by restoring mitochondrial dysfunction in mice.
Klotho enhances bone regenerative function of hPDLSCs via modulating immunoregulatory function and cell autophagy.
Radiation resistance of cancer cells caused by mitochondrial dysfunction depends on SIRT3-mediated mitophagy.
Paeoniflorin suppresses kidney inflammation by regulating macrophage polarization via KLF4-mediated mitophagy.
Mechanical force induces mitophagy-mediated anaerobic oxidation in periodontal ligament stem cells.
Silibinin alleviates ferroptosis of rat islet β cell INS-1 induced by the treatment with palmitic acid and high glucose through enhancing PINK1/parkin-mediated mitophagy.
S-Doped carbonized polymer dots inhibit early myocardial fibrosis by regulating mitochondrial function.
Electroacupuncture ameliorates surgery-induced spatial memory deficits by promoting mitophagy in rats.
Multi-Targeting Intranasal Nanoformulation as a Therapeutic for Alzheimer's Disease.
CXCR3 Inhibition Blocks the NF-κB Signaling Pathway by Elevating Autophagy to Ameliorate Lipopolysaccharide-Induced Intestinal Dysfunction in Mice.
Placental Mesenchymal Stem Cells Alleviate Podocyte Injury in Diabetic Kidney Disease by Modulating Mitophagy via the SIRT1-PGC-1alpha-TFAM Pathway.
Conjugation of Macrophage-Mimetic Microalgae and Liposome for Antitumor Sonodynamic Immunotherapy via Hypoxia Alleviation and Autophagy Inhibition.
Stomatin-like protein 2 deficiency exacerbates adverse cardiac remodeling.
MLKL deficiency attenuated hepatocyte oxidative DNA damage by activating mitophagy to suppress macrophage cGAS-STING signaling during liver ischemia and reperfusion injury.
Zinc Overload Induces Damage to H9c2 Cardiomyocyte Through Mitochondrial Dysfunction and ROS-Mediated Mitophagy.
Stimulator of interferon genes promotes diabetic sarcopenia by targeting peroxisome proliferator activated receptors γ degradation and inhibiting fatty acid oxidation.
Ginsenoside Rb1 protects hippocampal neurons in depressed rats based on mitophagy-regulated astrocytic pyroptosis.
Effects of dapagliflozin monotherapy and combined aerobic exercise on skeletal muscle mitochondrial quality control and insulin resistance in type 2 diabetes mellitus rats.
Neuronal-specific TNFAIP1 ablation attenuates postoperative cognitive dysfunction via targeting SNAP25 for K48-linked ubiquitination.
Mitophagy-dependent cardioprotection of resistance training on heart failure.
Zinc oxide nanoparticles induce toxicity in diffuse large B-cell lymphoma cell line U2932 via activating PINK1/Parkin-mediated mitophagy.
Deficiency of Pink1 promotes the differentiation of Th1 cells.
PPARγ activation suppresses chondrocyte ferroptosis through mitophagy in osteoarthritis.
Diosgenin Targets CaMKK2 to Alleviate Type II Diabetic Nephropathy through Improving Autophagy, Mitophagy and Mitochondrial Dynamics.
Loganin alleviated cognitive impairment in 3×Tg-AD mice through promoting mitophagy mediated by optineurin.
CERS6-derived ceramides aggravate kidney fibrosis by inhibiting PINK1-mediated mitophagy in diabetic kidney disease.
The effect of PINK1/Parkin pathway on glucose homeostasis imbalance induced by tacrolimus in mouse livers.
Study of the mechanism underlying the role of PINK1/Parkin in the formic acid-induced autophagy of PC12 cells.
ATG2B upregulated in LPS-stimulated BMSCs-derived exosomes attenuates septic liver injury by inhibiting macrophage STING signaling.
TOM complex-independent transport pathway of myoglobin into mitochondria in C2C12 myotubes.
Inhibition of PINK1-Mediated Mitophagy Contributes to Postoperative Cognitive Dysfunction through Activation of Caspase-3/GSDME-Dependent Pyroptosis.
Ginsenoside Rb1 alleviated concanavalin A-induced hepatocyte pyroptosis by activating mitophagy.
PRKAA1 induces aberrant mitophagy in a PINK1/Parkin-dependent manner, contributing to fluoride-induced developmental neurotoxicity.
Melatonin ameliorates glyphosate- and hard water-induced renal tubular epithelial cell senescence via PINK1-Parkin-dependent mitophagy.
Effects of short-term endurance and strength exercise in the molecular regulation of skeletal muscle in hyperinsulinemic and hyperglycemic Slc2a4(+/-) mice.
MTMR14 Alleviates Chronic Obstructive Pulmonary Disease as a Regulator in Inflammation and Emphysema.
Astragaloside IV Protects Detrusor from Partial Bladder Outlet Obstruction-Induced Oxidative Stress by Activating Mitophagy through AMPK-ULK1 Pathway.
Xuesaitong Combined with Dexmedetomidine Improves Cerebral Ischemia-Reperfusion Injury in Rats by Activating Keap1/Nrf2 Signaling and Mitophagy in Hippocampal Tissue.
Astrocytic IGF-1 and IGF-1R Orchestrate Mitophagy in Traumatic Brain Injury via Exosomal miR-let-7e.
Transcutaneous Electrical Acupoint Stimulation Ameliorates Cognitive Function through PINK1/Parkin Mediated Mitophagy in VD Rats.
San-Huang-Yi-Shen Capsule Ameliorates Diabetic Kidney Disease through Inducing PINK1/Parkin-Mediated Mitophagy and Inhibiting the Activation of NLRP3 Signaling Pathway.
Maltol Promotes Mitophagy and Inhibits Oxidative Stress via the Nrf2/PINK1/Parkin Pathway after Spinal Cord Injury.
The inhibition of PGAM5 suppresses seizures in a kainate-induced epilepsy model via mitophagy reduction.
Ginkgolide B Protects Against Ischemic Stroke via Targeting AMPK/PINK1.
Reduced Immunity Regulator MAVS Contributes to Non-Hypertrophic Cardiac Dysfunction by Disturbing Energy Metabolism and Mitochondrial Homeostasis.
Heat Shock Transcription Factor 2 Promotes Mitophagy of Intestinal Epithelial Cells Through PARL/PINK1/Parkin Pathway in Ulcerative Colitis.
Number 2 Feibi Recipe Inhibits H(2)O(2)-Mediated Oxidative Stress Damage of Alveolar Epithelial Cells by Regulating the Balance of Mitophagy/Apoptosis.
Harpagoside Protects Against Doxorubicin-Induced Cardiotoxicity via P53-Parkin-Mediated Mitophagy.
Restoration of mitophagy ameliorates cardiomyopathy in Barth syndrome.
Elevated SFXN2 limits mitochondrial autophagy and increases iron-mediated energy production to promote multiple myeloma cell proliferation.
Inhibition of autophagy with chloroquine dysregulates mitochondrial quality control and energetics in adipocytes.
Comparing the mitochondrial signatures in ESCs and iPSCs and their neural derivations.
Omentin1 ameliorates myocardial ischemia-induced heart failure via SIRT3/FOXO3a-dependent mitochondrial dynamical homeostasis and mitophagy.
The oncoprotein MUC1 facilitates breast cancer progression by promoting Pink1-dependent mitophagy via ATAD3A destabilization.
Mitophagy induced by classical swine fever virus nonstructural protein 5A promotes viral replication.
Anti-ANGPTL3-FLD monoclonal antibody treatment ameliorates podocyte lesions through attenuating mitochondrial damage.
Effects of ferulic acid, a major component of rice bran, on proliferation, apoptosis, and autophagy of HepG2 cells.
Cadmium-induced apoptosis of Leydig cells is mediated by excessive mitochondrial fission and inhibition of mitophagy.
Salidroside reduces neuropathology in Alzheimer's disease models by targeting NRF2/SIRT3 pathway.
O-GlcNAcylation of SIRT1 Protects against Cold Stress-Induced Skeletal Muscle Damage via Amelioration of Mitochondrial Homeostasis.
Effective-component compatibility of Bufei Yishen formula III ameliorated COPD by improving airway epithelial cell senescence by promoting mitophagy via the NRF2/PINK1 pathway.
Inhibition of human peptide deformylase by actinonin sensitizes glioblastoma cells to temozolomide chemotherapy.
Repeated social defeat stress inhibits development of hippocampus neurons through mitophagy and autophagy.
Dl-3-n-butylphthalide attenuates myocardial ischemia reperfusion injury by suppressing oxidative stress and regulating cardiac mitophagy via the PINK1/Parkin pathway in rats.
Ivermectin-Induced Apoptotic Cell Death in Human SH-SY5Y Cells Involves the Activation of Oxidative Stress and Mitochondrial Pathway and Akt/mTOR-Pathway-Mediated Autophagy.
Apigenin alleviated PA-induced pyroptosis by activating autophagy in hepatocytes.
Cardioprotective effect of ginsenoside Rb1 via regulating metabolomics profiling and AMP-activated protein kinase-dependent mitophagy.
Maintaining homeostasis of mitochondria and endoplasmic reticulum with NSC228155 alleviates cisplatin-induced acute kidney injury.
PINK1 regulates mitochondrial fission/fusion and neuroinflammation in β-amyloid-induced Alzheimer's disease models.
Involvement of NEAT1/PINK1-mediated mitophagy in chronic obstructive pulmonary disease induced by cigarette smoke or PM(2.5).
Chicoric Acid Attenuated Renal Tubular Injury in HFD-Induced Chronic Kidney Disease Mice through the Promotion of Mitophagy via the Nrf2/PINK/Parkin Pathway.
Dioscin relieves diabetic nephropathy via suppressing oxidative stress and apoptosis, and improving mitochondrial quality and quantity control.
Mitophagy induced by UMI-77 preserves mitochondrial fitness in renal tubular epithelial cells and alleviates renal fibrosis.
A novel PHD2 inhibitor acteoside from Cistanche tubulosa induces skeletal muscle mitophagy to improve cancer-related fatigue.
Exercise training improves cardiac function and regulates myocardial mitophagy differently in ischaemic and pressure-overload heart failure mice.
Transcription factor nuclear factor erythroid 2 p45-related factor 2 (NRF2) ameliorates sepsis-associated acute kidney injury by maintaining mitochondrial homeostasis and improving the mitochondrial function.
Oxidative stress from DGAT1 oncoprotein inhibition in melanoma suppresses tumor growth when ROS defenses are also breached.
Integrated metabolism and epigenetic modifications in the macrophages of mice in responses to cold stress.
Ophiopogonin D'-induced mitophagy and mitochondrial damage are associated with dysregulation of the PINK1/Parkin signaling pathway in AC16 cells.
Effects of Wenyang Zhenshuai Granules on the Expression of Key Mitochondrial Autophagy Proteins in the Doxorubicin-Induced Model of H9c2 Cardiomyocyte Injury.
Resveratrol alleviates enterotoxigenic Escherichia coli K88-induced damage by regulating SIRT-1 signaling in intestinal porcine epithelial cells.
Jujuboside A ameliorates high fat diet and streptozotocin induced diabetic nephropathy via suppressing oxidative stress, apoptosis, and enhancing autophagy.
Bombyx mori cypovirus (BmCPV) induces PINK1-Parkin mediated mitophagy via interaction of VP4 with host Tom40.
Interfering with mitochondrial dynamics sensitizes glioblastoma multiforme to temozolomide chemotherapy.
Deoxyhypusine hydroxylase as a novel pharmacological target for ischemic stroke via inducing a unique post-translational hypusination modification.
Salvianolic acid B alleviates diabetic endothelial and mitochondrial dysfunction by down-regulating apoptosis and mitophagy of endothelial cells.
Tourniquet-induced lower limb ischemia/reperfusion reduces mitochondrial function by decreasing mitochondrial biogenesis in acute kidney injury in mice.
Disuse-associated loss of the protease LONP1 in muscle impairs mitochondrial function and causes reduced skeletal muscle mass and strength.
Mitochondria-Dependent Oxidative Stress Mediates ZnO Nanoparticle (ZnO NP)-Induced Mitophagy and Lipotoxicity in Freshwater Teleost Fish.
Nano-graphene oxide depresses neurotransmission by blocking retrograde transport of mitochondria.
Polygala saponins inhibit NLRP3 inflammasome-mediated neuroinflammation via SHP-2-Mediated mitophagy.
RNA sequence analysis reveals pathways and candidate genes associated with pancreatic acinar cells injury in a mouse pancreatitis model.
Phytosphingosine-induced cell apoptosis via a mitochondrially mediated pathway.
The SMYD3-MTHFD1L-formate metabolic regulatory axis mediates mitophagy to inhibit M1 polarization in macrophages.
Stomatin-like protein-2 attenuates macrophage pyroptosis and H9c2 cells apoptosis by protecting mitochondrial function.
Glucagon-like Peptide 1 Receptor Activation Inhibits Microglial Pyroptosis via Promoting Mitophagy to Alleviate Depression-like Behaviors in Diabetic Mice.
PINK1 overexpression prevents forskolin-induced tau hyperphosphorylation and oxidative stress in a rat model of Alzheimer's disease.
CDK9 inhibition blocks the initiation of PINK1-PRKN-mediated mitophagy by regulating the SIRT1-FOXO3-BNIP3 axis and enhances the therapeutic effects involving mitochondrial dysfunction in hepatocellular carcinoma.
The Degradation of TMEM166 by Autophagy Promotes AMPK Activation to Protect SH-SY5Y Cells Exposed to MPP().
Development of artesunate intelligent prodrug liposomes based on mitochondrial targeting strategy.
Melatonin Attenuates Ropivacaine-Induced Apoptosis by Inhibiting Excessive Mitophagy Through the Parkin/PINK1 Pathway in PC12 and HT22 Cells.
SIRT2 Is Critical for Sheep Oocyte Maturation through Regulating Function of Surrounding Granulosa Cells.
Exercise activates autophagy and regulates endoplasmic reticulum stress in muscle of high-fat diet mice to alleviate insulin resistance.
Flubendazole induces mitochondrial dysfunction and DRP1-mediated mitophagy by targeting EVA1A in breast cancer.
Urolithin A promotes mitophagy and suppresses NLRP3 inflammasome activation in lipopolysaccharide-induced BV2 microglial cells and MPTP-induced Parkinson's disease model.
Bhlhe40/Sirt1 Axis-Regulated Mitophagy Is Implicated in All-Trans Retinoic Acid-Induced Spina Bifida Aperta.
Samm50 Promotes Hypertrophy by Regulating Pink1-Dependent Mitophagy Signaling in Neonatal Cardiomyocytes.
Knockdown of VDAC1 alleviates the cognitive dysfunction secondary to sepsis-associated encephalopathy.
SARS-CoV-2 Causes Mitochondrial Dysfunction and Mitophagy Impairment.
Aldehyde Dehydrogenase 2 Protects Against Lipopolysaccharide-Induced Myocardial Injury by Suppressing Mitophagy.
Astragaloside II Ameliorated Podocyte Injury and Mitochondrial Dysfunction in Streptozotocin-Induced Diabetic Rats.
A Mitochondrial DNA Variant Elevates the Risk of Gallstone Disease by Altering Mitochondrial Function.
HIF-1-induced mitochondrial ribosome protein L52: a mechanism for breast cancer cellular adaptation and metastatic initiation in response to hypoxia.
Trimetazidine and exercise provide comparable improvements to high fat diet-induced muscle dysfunction through enhancement of mitochondrial quality control.
The protection of selenium against cadmium-induced mitophagy via modulating nuclear xenobiotic receptors response and oxidative stress in the liver of rabbits.
Moderate mechanical stress suppresses the IL-1β-induced chondrocyte apoptosis by regulating mitochondrial dynamics.
Suppressing TRAP1 sensitizes glioblastoma multiforme cells to temozolomide.
Maternal selenium deficiency suppresses proliferation, induces autophagy dysfunction and apoptosis in the placenta of mice.
Neurotoxicity of a pyrethroid pesticide deltamethrin is associated with the imbalance in proteolytic systems caused by mitophagy activation and proteasome inhibition.
Biosynthetic gold nanoparticles of Hibiscus syriacus L. callus potentiates anti-inflammation efficacy via an autophagy-dependent mechanism.
PINK1 contained in huMSC-derived exosomes prevents cardiomyocyte mitochondrial calcium overload in sepsis via recovery of mitochondrial Ca(2+) efflux.
Scutellarin ameliorates high glucose-induced vascular endothelial cells injury by activating PINK1/Parkin-mediated mitophagy.
Electroacupuncture at GV20‑GB7 regulates mitophagy to protect against neurological deficits following intracerebral hemorrhage via inhibition of apoptosis.
Autophagy regulates functional differentiation of mammary epithelial cells.
Exercise alters the mitochondrial proteostasis and induces the mitonuclear imbalance and UPR(mt) in the hypothalamus of mice.
Dynamic observation of 5-fluorouracil-induced myocardial injury and mitochondrial autophagy in aging rats.
Citrus alkaline extracts prevent endoplasmic reticulum stress in type II alveolar epithelial cells to ameliorate pulmonary fibrosis via the ATF3/PINK1 pathway.
Biosynthesis of gold nanoparticles using Nigella sativa and Curtobacterium proimmune K3 and evaluation of their anticancer activity.
Effects of the Cytoplasm and Mitochondrial Specific Hydroxyl Radical Scavengers TA293 and mitoTA293 in Bleomycin-Induced Pulmonary Fibrosis Model Mice.
An Experimentally Induced Mutation in the UBA Domain of p62 Changes the Sensitivity of Cisplatin by Up-Regulating HK2 Localisation on the Mitochondria and Increasing Mitophagy in A2780 Ovarian Cancer Cells.
Mitochondria-targeted magnolol inhibits OXPHOS, proliferation, and tumor growth via modulation of energetics and autophagy in melanoma cells.
Ginseng-Sanqi-Chuanxiong (GSC) Extracts Ameliorate Diabetes-Induced Endothelial Cell Senescence through Regulating Mitophagy via the AMPK Pathway.
Bcl-2 Proteins Regulate Mitophagy in Lipopolysaccharide-Induced Acute Lung Injury via PINK1/Parkin Signaling Pathway.
Deletion of mitochondrial uncoupling protein 2 exacerbates mitophagy and cell apoptosis after cerebral ischemia and reperfusion injury in mice.
Chaetomugilin J Enhances Apoptosis in Human Ovarian Cancer A2780 Cells Induced by Cisplatin Through Inhibiting Pink1/Parkin Mediated Mitophagy.
Neuroprotective Role of GLP-1 Analog for Retinal Ganglion Cells via PINK1/Parkin-Mediated Mitophagy in Diabetic Retinopathy.
Metformin mitigates gastrointestinal radiotoxicity and radiosensitises P53 mutation colorectal tumours via optimising autophagy.
miR-103a-3p regulates mitophagy in Parkinson's disease through Parkin/Ambra1 signaling.
Disease-specific phenotypes in iPSC-derived neural stem cells with POLG mutations.
Cr (VI) induced mitophagy via the interaction of HMGA2 and PARK2.
Novel ultrastructural findings on cardiac mitochondria of huddling Brandt's voles in mild cold environment.
Arsenic induces hepatic insulin resistance via mtROS-NLRP3 inflammasome pathway.
Treadmill Exercise Attenuates Aβ-Induced Mitochondrial Dysfunction and Enhances Mitophagy Activity in APP/PS1 Transgenic Mice.
Nestin protects podocyte from injury in lupus nephritis by mitophagy and oxidative stress.
Silibinin-induced mitochondria fission leads to mitophagy, which attenuates silibinin-induced apoptosis in MCF-7 and MDA-MB-231 cells.
FSH prevents porcine granulosa cells from hypoxia-induced apoptosis via activating mitophagy through the HIF-1α-PINK1-Parkin pathway.
lncRNA RMST Suppressed GBM Cell Mitophagy through Enhancing FUS SUMOylation.
ChREBP-β regulates thermogenesis in brown adipose tissue.
DNA damage invokes mitophagy through a pathway involving Spata18.
Qiliqiangxin reduced cardiomyocytes apotosis and improved heart function in infarcted heart through Pink1/Parkin -mediated mitochondrial autophagy.
Fluoride induced mitochondrial impairment and PINK1-mediated mitophagy in Leydig cells of mice: In vivo and in vitro studies.
Lactobacillus johnsonii L531 ameliorates enteritis via elimination of damaged mitochondria and suppression of SQSTM1-dependent mitophagy in a Salmonella infantis model of piglet diarrhea.
NIPA2 regulates osteoblast function by modulating mitophagy in type 2 diabetes osteoporosis.
Deregulated MTOR (mechanistic target of rapamycin kinase) is responsible for autophagy defects exacerbating kidney stone development.
Exogenous H(2)S Promoted USP8 Sulfhydration to Regulate Mitophagy in the Hearts of db/db Mice.
FOXO3 protects nucleus pulposus cells against apoptosis under nutrient deficiency via autophagy.
PINK1/Parkin-Mediated Mitophagy Regulation by Reactive Oxygen Species Alleviates Rocaglamide A-Induced Apoptosis in Pancreatic Cancer Cells.
Hepatic DNA Damage Induced by Electronic Cigarette Exposure Is Associated With the Modulation of NAD+/PARP1/SIRT1 Axis.
Bone marrow mesenchymal stem cells repair Cr (VI)- injured kidney by regulating mitochondria-mediated apoptosis and mitophagy mediated via the MAPK signaling pathway.
Liraglutide ameliorates non-alcoholic steatohepatitis by inhibiting NLRP3 inflammasome and pyroptosis activation via mitophagy.
In mammalian skeletal muscle, phosphorylation of TOMM22 by protein kinase CSNK2/CK2 controls mitophagy.
Mitophagy Directs Muscle-Adipose Crosstalk to Alleviate Dietary Obesity.
PHB2 interacts with LC3 and SQSTM1 is required for bile acids-induced mitophagy in cholestatic liver.
Involvement of PINK1/Parkin-mediated mitophagy in paraquat- induced apoptosis in human lung epithelial-like A549 cells.
Florfenicol-induced Mitochondrial Dysfunction Suppresses Cell Proliferation and Autophagy in Fibroblasts.
Polyubiquitination of apurinic/apyrimidinic endonuclease 1 by Parkin.
ABT737 induces mitochondrial pathway apoptosis and mitophagy by regulating DRP1-dependent mitochondrial fission in human ovarian cancer cells.
Wang ZY, Chen RX, Wang JF, Liu SC, Xu X, Zhou T, Chen YAL, Zhang YD, Li XC, Li CX
Cellular and molecular gastroenterology and hepatology 2024;17(4):539-551
Cellular and molecular gastroenterology and hepatology 2024;17(4):539-551
NAD-Dependent Protein Deacetylase Sirtuin-1 Mediated Mitophagy Regulates Early Brain Injury After Subarachnoid Hemorrhage.
Wang G, Lin N
Journal of inflammation research 2024;17:1971-1981
Journal of inflammation research 2024;17:1971-1981
Involvement of autophagy in mesaconitine-induced neurotoxicity in HT22 cells revealed through integrated transcriptomic, proteomic, and m6A epitranscriptomic profiling.
Lin X, Zhang J, Wu Z, Shi Y, Chen M, Li M, Hu H, Tian K, Lv X, Li C, Liu Y, Gao X, Yang Q, Chen K, Zhu A
Frontiers in pharmacology 2024;15:1393717
Frontiers in pharmacology 2024;15:1393717
Sestrin2 remedies neuroinflammatory response by inhibiting A1 astrocyte conversion via autophagy.
Pan Z, Yu X, Wang W, Shen K, Chen J, Zhang Y, Huang R
Journal of neurochemistry 2024 Sep;168(9):2640-2653
Journal of neurochemistry 2024 Sep;168(9):2640-2653
Human neural stem cells promote mitochondrial genesis to alleviate neuronal damage in MPTP-induced cynomolgus monkey models.
He Y, Li R, Yu Y, Huang C, Xu Z, Wang T, Chen M, Huang H, Qi Z
Neurochemistry international 2024 May;175:105700
Neurochemistry international 2024 May;175:105700
BMAL1 alleviates myocardial damage in sepsis by activating SIRT1 signaling and promoting mitochondrial autophagy.
Tang W, Guo R, Hu C, Yang Y, Yang D, Chen X, Liu Y
International immunopharmacology 2024 May 30;133:112111
International immunopharmacology 2024 May 30;133:112111
Exploring the neuroprotective role of artesunate in mouse models of anti-NMDAR encephalitis: insights from molecular mechanisms and transmission electron microscopy.
Liu J, Huang Y, Qian T, Chen J, Ding Y, Lai Z, Zhong X, Lai M, Zhang H, Wang Y, Wang H, Peng Y
Cell communication and signaling : CCS 2024 May 14;22(1):269
Cell communication and signaling : CCS 2024 May 14;22(1):269
Collagen I protects human keratinocytes HaCaT against UVB injury via restoring PINK1/parkin-mediated mitophagy.
Zhu Y, Xiang W, He S, San Z, Liu W, Wu J, Hayashi T, Mizuno K, Hattori S, Fujisaki H, Ikejima T
Archives of biochemistry and biophysics 2024 Mar;753:109905
Archives of biochemistry and biophysics 2024 Mar;753:109905
L-Citrulline Ameliorates Iron Metabolism and Mitochondrial Quality Control via Activating AMPK Pathway in Intestine and Improves Microbiota in Mice with Iron Overload.
Zhao D, Gao Y, Chen Y, Zhang Y, Deng Y, Niu S, Dai H
Molecular nutrition & food research 2024 Mar;68(6):e2300723
Molecular nutrition & food research 2024 Mar;68(6):e2300723
Alpha-ketoglutaric acid attenuates oxidative stress and modulates mitochondrial dynamics and autophagy of spleen in a piglet model of lipopolysaccharide-induced sepsis.
Liu G, Lu J, Sun W, Jia G, Zhao H, Chen X, Wang J
Free radical biology & medicine 2024 Mar;214:80-86
Free radical biology & medicine 2024 Mar;214:80-86
The opposite role of lactate dehydrogenase a (LDHA) in cervical cancer under energy stress conditions.
Jia C, Wu Y, Gao F, Liu W, Li N, Chen Y, Sun L, Wang S, Yu C, Bao Y, Song Z
Free radical biology & medicine 2024 Mar;214:2-18
Free radical biology & medicine 2024 Mar;214:2-18
Propionate promotes ferroptosis and apoptosis through mitophagy and ACSL4-mediated ferroptosis elicits anti-leukemia immunity.
Wei Y, Liu W, Wang R, Chen Y, Liu J, Guo X, Can C, Yang X, Wang D, Hu X, Ma D
Free radical biology & medicine 2024 Mar;213:36-51
Free radical biology & medicine 2024 Mar;213:36-51
Ubiquitinome Analysis Uncovers Alterations in Synaptic Proteins and Glucose Metabolism Enzymes in the Hippocampi of Adolescent Mice Following Cold Exposure.
Li XY, Yin X, Lu JJ, Li QR, Xing WQ, Han Q, Ji H, Li SZ, Yang HM, Guo JR, Wang ZQ, Xu B
Cells 2024 Mar 25;13(7)
Cells 2024 Mar 25;13(7)
The HRI branch of the integrated stress response selectively triggers mitophagy.
Chakrabarty Y, Yang Z, Chen H, Chan DC
Molecular cell 2024 Mar 21;84(6):1090-1100.e6
Molecular cell 2024 Mar 21;84(6):1090-1100.e6
Loss of FoxO1 activates an alternate mechanism of mitochondrial quality control for healthy adipose browning.
Shi L, Yang J, Tao Z, Zheng L, Bui TF, Alonso RL, Yue F, Cheng Z
Clinical science (London, England : 1979) 2024 Mar 20;138(6):371-385
Clinical science (London, England : 1979) 2024 Mar 20;138(6):371-385
The mitochondrial UPR induced by ATF5 attenuates intervertebral disc degeneration via cooperating with mitophagy.
Xu WN, Zheng HL, Yang RZ, Sun YF, Peng BR, Liu C, Song J, Jiang SD, Zhu LX
Cell biology and toxicology 2024 Mar 13;40(1):16
Cell biology and toxicology 2024 Mar 13;40(1):16
TBBPS caused necroptosis and inflammation in hepatocytes by blocking PINK1-PARKIN-mediated mitochondrial autophagy.
Yin Y, Huang M, Xie J, Ou Y, Mai T
Tissue & cell 2024 Jun;88:102382
Tissue & cell 2024 Jun;88:102382
Atox1 protects hippocampal neurons after traumatic brain injury via DJ-1 mediated anti-oxidative stress and mitophagy.
Zhao P, Shi W, Ye Y, Xu K, Hu J, Chao H, Tao Z, Xu L, Gu W, Zhang L, Wang T, Wang X, Ji J
Redox biology 2024 Jun;72:103156
Redox biology 2024 Jun;72:103156
Urolithin A improves Alzheimer's disease cognition and restores mitophagy and lysosomal functions.
Hou Y, Chu X, Park JH, Zhu Q, Hussain M, Li Z, Madsen HB, Yang B, Wei Y, Wang Y, Fang EF, Croteau DL, Bohr VA
Alzheimer's & dementia : the journal of the Alzheimer's Association 2024 Jun;20(6):4212-4233
Alzheimer's & dementia : the journal of the Alzheimer's Association 2024 Jun;20(6):4212-4233
Modulating synovial macrophage pyroptosis and mitophagy interactions to mitigate osteoarthritis progression using functionalized nanoparticles.
Qi W, Jin L, Huang S, Aikebaier A, Xue S, Wang Q, Chen Q, Lu Y, Ding C
Acta biomaterialia 2024 Jun;181:425-439
Acta biomaterialia 2024 Jun;181:425-439
The regulation of MFG-E8 on the mitophagy in diabetic sarcopenia via the HSPA1L-Parkin pathway and the effect of D-pinitol.
Zhao W, Zhao B, Meng X, Li B, Wang Y, Yu F, Fu C, Yu X, Li X, Dai C, Wang J, Gao H, Cheng M
Journal of cachexia, sarcopenia and muscle 2024 Jun;15(3):934-948
Journal of cachexia, sarcopenia and muscle 2024 Jun;15(3):934-948
Thiosemicarbazone Mixed-Valence Cu(I/II) Complex against Lung Adenocarcinoma Cells through Multiple Pathways Involving Cuproptosis.
Li A, Huang K, Pan W, Wu Y, Liang Y, Zhang Z, Wu D, Ma L, Gou Y
Journal of medicinal chemistry 2024 Jun 13;67(11):9091-9103
Journal of medicinal chemistry 2024 Jun 13;67(11):9091-9103
HO-1 upregulation promotes mitophagy-dependent ferroptosis in PM2.5-exposed hippocampal neurons.
Li X, Ran Q, He X, Peng D, Xiong A, Jiang M, Zhang L, Wang J, Bai L, Liu S, Li S, Sun B, Li G
Ecotoxicology and environmental safety 2024 Jun 1;277:116314
Ecotoxicology and environmental safety 2024 Jun 1;277:116314
Adenylate kinase 4 promotes neuronal energy metabolism and mitophagy in early cerebral ischemia via Parkin/PKM2 pathway.
Zhong Y, Jia B, Xie C, Hu L, Liao Z, Liu W, Zhang Y, Huang G
Experimental neurology 2024 Jul;377:114798
Experimental neurology 2024 Jul;377:114798
Mechanism Research of DHEA Treatment Improving Diminished Ovarian Reserve by Attenuating the AMPK-SIRT1 Signaling and Mitophagy.
Ma Q, Shen M, Wu J, Ye C, Tan Y
Reproductive sciences (Thousand Oaks, Calif.) 2024 Jul;31(7):2059-2072
Reproductive sciences (Thousand Oaks, Calif.) 2024 Jul;31(7):2059-2072
Mitochondria-targeted ruthenium complexes can be generated in vitro and in living cells to target triple-negative breast cancer cells by autophagy inhibition.
Zhang GD, Wang MM, Su Y, Fang H, Xue XL, Liu HK, Su Z
Journal of inorganic biochemistry 2024 Jul;256:112574
Journal of inorganic biochemistry 2024 Jul;256:112574
THSG alleviates cerebral ischemia/reperfusion injury via the GluN2B-CaMKII-ERK1/2 pathway.
Liu T, Shi J, Wu D, Li D, Wang Y, Liu J, Meng P, Hu L, Fu C, Mei Z, Ge J, Zhang X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155595
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155595
Drp1 regulated PINK1-dependent mitophagy protected duck follicular granulosa cells from acute heat stress injury.
Yang C, Luo P, Yang YT, Fu XL, Li BX, Shen X, Xu DN, Huang YM, Tian YB, Liu WJ
Poultry science 2024 Jan;103(1):103247
Poultry science 2024 Jan;103(1):103247
Suppression of NLRP3 inflammasome activation by astragaloside IV via promotion of mitophagy to ameliorate radiation-induced renal injury in mice.
Ding Y, Liu S, Zhang M, Su M, Shao B
Translational andrology and urology 2024 Jan 31;13(1):25-41
Translational andrology and urology 2024 Jan 31;13(1):25-41
Melatonin protects against myocardial ischemia-reperfusion injury by inhibiting excessive mitophagy through the Apelin/SIRT3 signaling axis.
Wang Z, Lin D, Cui B, Zhang D, Wu J, Ma J
European journal of pharmacology 2024 Jan 15;963:176292
European journal of pharmacology 2024 Jan 15;963:176292
Activation of mitophagy improves cognitive dysfunction in diabetic mice with recurrent non-severe hypoglycemia.
Wu K, Huang C, Zheng W, Wu Y, Huang Q, Lin M, Gao R, Qi L, He G, Liu X, Liu X, Wang L, Chen Z, Liu L
Molecular and cellular endocrinology 2024 Jan 15;580:112109
Molecular and cellular endocrinology 2024 Jan 15;580:112109
Fluorochloridone induces mitochondrial dysfunction and apoptosis in primary goat Sertoli cells.
Li Y, Li L, Xiong W, Duan X, Xi H
Theriogenology 2024 Jan 15;214:192-200
Theriogenology 2024 Jan 15;214:192-200
ErZhiTianGui Decoction alleviates age-related ovarian aging by regulating mitochondrial homeostasis and inhibiting ferroptosis.
Zhicheng J, Yongqian L, Peixuan W, Kai Y, Mengyu S, Wen C, Qihui L, Ying G
Journal of ovarian research 2024 Jan 10;17(1):12
Journal of ovarian research 2024 Jan 10;17(1):12
Modeling drug-induced mitochondrial toxicity with human primary cardiomyocytes.
Tang X, Liu H, Rao R, Huang Y, Dong M, Xu M, Feng S, Shi X, Wang L, Wang Z, Zhou B
Science China. Life sciences 2024 Feb;67(2):301-319
Science China. Life sciences 2024 Feb;67(2):301-319
Control of NAD(+) homeostasis by autophagic flux modulates mitochondrial and cardiac function.
Zhang Q, Li Z, Li Q, Trammell SA, Schmidt MS, Pires KM, Cai J, Zhang Y, Kenny H, Boudina S, Brenner C, Abel ED
The EMBO journal 2024 Feb;43(3):362-390
The EMBO journal 2024 Feb;43(3):362-390
Blockade of angiotensin II modulates insulin-like growth factor 1-mediated skeletal muscle homeostasis in experimental steatohepatitis.
Tanaka M, Kaji K, Nishimura N, Asada S, Koizumi A, Matsuda T, Yorioka N, Tsuji Y, Fujinaga Y, Sato S, Namisaki T, Akahane T, Yoshiji H
Biochimica et biophysica acta. Molecular cell research 2024 Feb;1871(2):119649
Biochimica et biophysica acta. Molecular cell research 2024 Feb;1871(2):119649
Cholesterol-induced HRD1 reduction accelerates vascular smooth muscle cell senescence via stimulation of endoplasmic reticulum stress-induced reactive oxygen species.
Wang L, Wang M, Niu H, Zhi Y, Li S, He X, Ren Z, Wen S, Wu L, Wen S, Zhang R, Wen Z, Yang J, Zhang X, Chen Y, Qian X, Shi G
Journal of molecular and cellular cardiology 2024 Feb;187:51-64
Journal of molecular and cellular cardiology 2024 Feb;187:51-64
Gonococcal OMV-delivered PorB induces epithelial cell mitophagy.
Gao S, Gao L, Yuan D, Lin X, van der Veen S
Nature communications 2024 Feb 23;15(1):1669
Nature communications 2024 Feb 23;15(1):1669
Circ-CIMIRC inhibition alleviates CIH-induced myocardial damage via FbxL4-mediated ubiquitination of PINK1.
Wu R, Xu F, Li J, Wang F, Chen N, Wang X, Chen Q
iScience 2024 Feb 16;27(2):108982
iScience 2024 Feb 16;27(2):108982
O-GlcNAcylation orchestrates porcine oocyte maturation through maintaining mitochondrial dynamics and function.
Xiong WJ, Lai XL, Lu J, Li LS, Zhang JX, Duan X
Molecular human reproduction 2024 Feb 1;30(2)
Molecular human reproduction 2024 Feb 1;30(2)
Geniposide effectively safeguards HT22 cells against Aβ-induced damage by activating mitophagy via the PINK1/Parkin signaling pathway.
Ye J, Wu J, Ai L, Zhu M, Li Y, Yin D, Huang Q
Biochemical pharmacology 2024 Aug;226:116296
Biochemical pharmacology 2024 Aug;226:116296
Zinc ions regulate mitochondrial quality control in neurons under oxidative stress and reduce PANoptosis in spinal cord injury models via the Lgals3-Bax pathway.
Bai M, Cui Y, Sang Z, Gao S, Zhao H, Mei X
Free radical biology & medicine 2024 Aug 20;221:169-180
Free radical biology & medicine 2024 Aug 20;221:169-180
SS-31 inhibits mtDNA-cGAS-STING signaling to improve POCD by activating mitophagy in aged mice.
Ji Y, Ma Y, Ma Y, Wang Y, Zhao X, Jin D, Xu L, Ge S
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2024 Apr;73(4):641-654
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2024 Apr;73(4):641-654
VDR regulates mitochondrial function as a protective mechanism against renal tubular cell injury in diabetic rats.
Chen H, Zhang H, Li AM, Liu YT, Liu Y, Zhang W, Yang C, Song N, Zhan M, Yang S
Redox biology 2024 Apr;70:103062
Redox biology 2024 Apr;70:103062
Rapamycin can alleviate the submandibular gland pathology of Sjögren's syndrome by limiting the activation of cGAS-STING signaling pathway.
Zhu W, Wang Y, Guan Y, Lu Y, Li Y, Sun L, Wang Y
Inflammopharmacology 2024 Apr;32(2):1113-1131
Inflammopharmacology 2024 Apr;32(2):1113-1131
SIRT3 alleviates painful diabetic neuropathy by mediating the FoxO3a-PINK1-Parkin signaling pathway to activate mitophagy.
Yang J, Yu Z, Jiang Y, Zhang Z, Tian Y, Cai J, Wei M, Lyu Y, Yang D, Shen S, Xing GG, Li M
CNS neuroscience & therapeutics 2024 Apr;30(4):e14703
CNS neuroscience & therapeutics 2024 Apr;30(4):e14703
Characterization and function of PTEN-induced putative kinase 1 (PINK1) in process of Zinc alleviates hepatic lipid deposition of yellow catfish (Pelteobagrus fulvidraco).
Xiao L, Chen B, Chen C, Xiao F, Li M, Zhuang M, Dai Y, Wu K
International journal of biological macromolecules 2024 Apr;265(Pt 2):131156
International journal of biological macromolecules 2024 Apr;265(Pt 2):131156
Resveratrol Inhibits Zinc Deficiency-Induced Mitophagy and Exerts Cardiac Cytoprotective Effects.
Wang P, Yang Y, Guo J, Ma T, Hu Y, Huang L, He Y, Xi J
Biological trace element research 2024 Apr;202(4):1669-1682
Biological trace element research 2024 Apr;202(4):1669-1682
The NLRX1-SLC39A7 complex orchestrates mitochondrial dynamics and mitophagy to rejuvenate intervertebral disc by modulating mitochondrial Zn(2+) trafficking.
Song Y, Liang H, Li G, Ma L, Zhu D, Zhang W, Tong B, Li S, Gao Y, Wu X, Zhang Y, Feng X, Wang K, Yang C
Autophagy 2024 Apr;20(4):809-829
Autophagy 2024 Apr;20(4):809-829
Chaihu Shugan Powder inhibits interstitial cells of cajal mitophagy through USP30 in the treatment of functional dyspepsia.
Wang X, Liu X, Wang Y, Yang K, Yeertai Y, Jia Q, Li L, Jiang K, Du G, Ling J
Journal of ethnopharmacology 2024 Apr 6;323:117695
Journal of ethnopharmacology 2024 Apr 6;323:117695
Targeting PARP14 with lomitapide suppresses drug resistance through the activation of DRP1-induced mitophagy in multiple myeloma.
Zhang H, Wang H, Hu Y, Gao Y, Chen J, Meng Y, Qiu Y, Hu R, Liao P, Li M, He Y, Liang Z, Xie X, Li Y
Cancer letters 2024 Apr 28;588:216802
Cancer letters 2024 Apr 28;588:216802
Iridium(III)-Based PD-L1 Agonist Regulates p62 and ATF3 for Enhanced Cancer Immunotherapy.
Deng D, Wang M, Su Y, Fang H, Chen Y, Su Z
Journal of medicinal chemistry 2024 Apr 25;67(8):6810-6821
Journal of medicinal chemistry 2024 Apr 25;67(8):6810-6821
A mitochondrial surveillance mechanism activated by SRSF2 mutations in hematologic malignancies.
Liu X, Devadiga SA, Stanley RF, Morrow R, Janssen K, Quesnel-Vallières M, Pomp O, Moverley AA, Li C, Skuli N, Carroll MP, Huang J, Wallace DC, Lynch KW, Abdel-Wahab O, Klein PS
bioRxiv : the preprint server for biology 2024 Apr 23;
bioRxiv : the preprint server for biology 2024 Apr 23;
Tetrandrine alleviates pulmonary fibrosis by inhibiting alveolar epithelial cell senescence through PINK1/Parkin-mediated mitophagy.
Chu L, Zhuo J, Huang H, Chen W, Zhong W, Zhang J, Meng X, Zou F, Cai S, Zou M, Dong H
European journal of pharmacology 2024 Apr 15;969:176459
European journal of pharmacology 2024 Apr 15;969:176459
Low-dose deoxynivalenol exposure inhibits hepatic mitophagy and hesperidin reverses this phenomenon by activating SIRT1.
Chen H, Xin W, Jiang J, Shan A, Ma J
Journal of hazardous materials 2024 Apr 15;468:133854
Journal of hazardous materials 2024 Apr 15;468:133854
TDCPP and TiO(2) NPs aggregates synergistically induce SH-SY5Y cell neurotoxicity by excessive mitochondrial fission and mitophagy inhibition.
Wang L, Wang B, Zhang X, Yang Z, Zhang X, Gong H, Song Y, Zhang K, Sun M
Environmental pollution (Barking, Essex : 1987) 2024 Apr 15;347:123740
Environmental pollution (Barking, Essex : 1987) 2024 Apr 15;347:123740
Mitophagy activation by rapamycin enhances mitochondrial function and cognition in 5×FAD mice.
Zheng W, Li K, Zhong M, Wu K, Zhou L, Huang J, Liu L, Chen Z
Behavioural brain research 2024 Apr 12;463:114889
Behavioural brain research 2024 Apr 12;463:114889
Icaritin with autophagy/mitophagy inhibitors synergistically enhances anticancer efficacy and apoptotic effects through PINK1/Parkin-mediated mitophagy in hepatocellular carcinoma.
Luo P, An Y, He J, Xing X, Zhang Q, Liu X, Chen Y, Yuan H, Chen J, Wong YK, Huang J, Gong Z, Du Q, Xiao W, Wang J
Cancer letters 2024 Apr 10;587:216621
Cancer letters 2024 Apr 10;587:216621
Corn peptides attenuate non-alcoholic fatty liver disease via PINK1/Parkin-mediated mitochondrial autophagy.
Yao Z, Li X, Wang W, Ren P, Song S, Wang H, Xie Y, Li X, Li Z
Food & nutrition research 2023;67
Food & nutrition research 2023;67
Dexmedetomidine Ameliorates Cardiac Ischemia/Reperfusion Injury by Enhancing Autophagy Through Activation of the AMPK/SIRT3 Pathway.
He H, Liu P, Li P
Drug design, development and therapy 2023;17:3205-3218
Drug design, development and therapy 2023;17:3205-3218
Electroacupuncture Exerts Chondroprotective Effect in Knee Osteoarthritis of Rabbits Through the Mitophagy Pathway.
Xing L, Chen X, Guo C, Zhu W, Hu T, Ma W, Du M, Xu Y, Guo C
Journal of pain research 2023;16:2871-2882
Journal of pain research 2023;16:2871-2882
Exercise prevents fatal stress-induced myocardial injury in obese mice.
Dun Y, Hu Z, You B, Du Y, Zeng L, Zhao Y, Liu Y, Wu S, Cui N, Yang F, Liu S
Frontiers in endocrinology 2023;14:1223423
Frontiers in endocrinology 2023;14:1223423
Exercise intervention improves mitochondrial quality in non-alcoholic fatty liver disease zebrafish.
Zou YY, Tang XB, Chen ZL, Liu B, Zheng L, Song MY, Xiao Q, Zhou ZQ, Peng XY, Tang CF
Frontiers in endocrinology 2023;14:1162485
Frontiers in endocrinology 2023;14:1162485
Buyang Huanwu Decoction alleviates cerebral ischemic injury through modulating caveolin-1-mediated mitochondrial quality control.
Xu Y, Chen B, Yi J, Tian F, Liu Y, Ouyang Y, Yuan C, Liu B
Frontiers in pharmacology 2023;14:1137609
Frontiers in pharmacology 2023;14:1137609
Role of Pink1-mediated mitophagy in adenomyosis.
Chen M, Wang W, Fu X, Yi Y, Wang K, Wang M
PeerJ 2023;11:e16497
PeerJ 2023;11:e16497
Knockdown of Y-box binding protein 1 induces autophagy in early porcine embryos.
Jiang WJ, Lee SH, Heo G, Chung HJ, Cho ES, Sa SJ, Hochi S, Cui XS
Frontiers in cell and developmental biology 2023;11:1238546
Frontiers in cell and developmental biology 2023;11:1238546
SNAP25 ameliorates postoperative cognitive dysfunction by facilitating PINK1-dependent mitophagy and impeding caspase-3/GSDME-dependent pyroptosis.
Wang W, Gao W, Zhang L, Xia Z, Zhao B
Experimental neurology 2023 Sep;367:114463
Experimental neurology 2023 Sep;367:114463
SIRT3 regulates mitophagy in liver fibrosis through deacetylation of PINK1/NIPSNAP1.
Li R, Wang Z, Wang Y, Sun R, Zou B, Tian X, Liu D, Zhao X, Zhou J, Zhao Y, Yao J
Journal of cellular physiology 2023 Sep;238(9):2090-2102
Journal of cellular physiology 2023 Sep;238(9):2090-2102
Hypoxia-induced GPCPD1 depalmitoylation triggers mitophagy via regulating PRKN-mediated ubiquitination of VDAC1.
Liu Y, Zhang H, Liu Y, Zhang S, Su P, Wang L, Li Y, Liang Y, Wang X, Zhao W, Chen B, Luo D, Zhang N, Yang Q
Autophagy 2023 Sep;19(9):2443-2463
Autophagy 2023 Sep;19(9):2443-2463
Aerobic exercise enhances mitochondrial homeostasis to counteract D-galactose-induced sarcopenia in zebrafish.
Chen ZL, Guo C, Zou YY, Feng C, Yang DX, Sun CC, Wen W, Jian ZJ, Zhao Z, Xiao Q, Zheng L, Peng XY, Zhou ZQ, Tang CF
Experimental gerontology 2023 Sep;180:112265
Experimental gerontology 2023 Sep;180:112265
Mitophagy contributes to zinc-induced ferroptosis in porcine testis cells.
Li Q, Yang Q, Guo P, Feng Y, Wang S, Guo J, Tang Z, Yu W, Liao J
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Sep;179:113950
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Sep;179:113950
AP39 inhibits ferroptosis by inhibiting mitochondrial autophagy through the PINK1/parkin pathway to improve myocardial fibrosis with myocardial infarction.
Yang T, Yang Q, Lai Q, Zhao J, Nie L, Liu S, Yang J, Chu C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115195
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115195
Loss and recovery of myocardial mitochondria in mice under different tail suspension time: Apoptosis and mitochondrial fission, fusion and autophagy.
Wang Z, Wang XC, Chen YF, Wang CL, Chen L, Jiang MY, Liu XW, Zhang XX, Feng YZ, Xu JH
Experimental physiology 2023 Sep;108(9):1189-1202
Experimental physiology 2023 Sep;108(9):1189-1202
MDM2 upregulation induces mitophagy deficiency via Mic60 ubiquitination in fetal microglial inflammation and consequently neuronal DNA damage caused by exposure to ZnO-NPs during pregnancy.
Zhang Y, Zhang Y, Lei Y, Wu J, Kang Y, Zheng S, Shao L
Journal of hazardous materials 2023 Sep 5;457:131750
Journal of hazardous materials 2023 Sep 5;457:131750
Long-Term Exposure to Microcystin-LR Induces Gastric Toxicity by Activating the Mitogen-Activated Protein Kinase Signaling Pathway.
Liu Y, Li Y, Tan Q, Lv Y, Tang Y, Yang Y, Yao X, Yang F
Toxins 2023 Sep 18;15(9)
Toxins 2023 Sep 18;15(9)
Co-exposure to environmentally relevant concentrations of cadmium and polystyrene nanoplastics induced oxidative stress, ferroptosis and excessive mitophagy in mice kidney.
Qiu W, Ye J, Su Y, Zhang X, Pang X, Liao J, Wang R, Zhao C, Zhang H, Hu L, Tang Z, Su R
Environmental pollution (Barking, Essex : 1987) 2023 Sep 15;333:121947
Environmental pollution (Barking, Essex : 1987) 2023 Sep 15;333:121947
Mitoquinone alleviates osteoarthritis progress by activating the NRF2-Parkin axis.
Hou L, Wang G, Zhang X, Lu F, Xu J, Guo Z, Lin J, Zheng Z, Liu H, Hou Y, Sun K, Guo F
iScience 2023 Sep 15;26(9):107647
iScience 2023 Sep 15;26(9):107647
The lysosome-mitochondrion crosstalk engaged in silver nanoparticles-disturbed mitochondrial homeostasis.
Liu J, Huang Z, Yin S, Zhou X, Jiang Y, Shao L
The Science of the total environment 2023 Sep 1;889:164078
The Science of the total environment 2023 Sep 1;889:164078
PTP1B knockdown alleviates BMSCs senescence via activating AMPK-mediated mitophagy and promotes osteogenesis in senile osteoporosis.
Yang Q, Zou Y, Wei X, Ye P, Wu Y, Ai H, Zhang Z, Tan J, Zhou J, Yang Y, Dai Q, Dou C, Luo F
Biochimica et biophysica acta. Molecular basis of disease 2023 Oct;1869(7):166795
Biochimica et biophysica acta. Molecular basis of disease 2023 Oct;1869(7):166795
3-MCPD Induced Mitochondrial Damage of Renal Cells Via the Rhythmic Protein BMAL1 Targeting SIRT3/SOD2.
Guan S, Wang Z, Zhang R, Chen S, Bu X, Lu J
Journal of agricultural and food chemistry 2023 Oct 4;71(39):14351-14364
Journal of agricultural and food chemistry 2023 Oct 4;71(39):14351-14364
Low expression of PINK1 and PARK2 predicts poor prognosis in patients with esophageal squamous cell carcinoma.
Lu X, Yao Y, Ma Y, Zhang X, Peng H, Pei Y, Lu Y, Wang L
World journal of surgical oncology 2023 Oct 13;21(1):321
World journal of surgical oncology 2023 Oct 13;21(1):321
N-acetylcysteine attenuates the incidence of phlebitis induced by carbomer/vinorelbine gel.
Zhang H, Gong J, Zhang S, Luo L, Luo C, Bi K, Wang L, Kan X, Tian Z, Wang X
Heliyon 2023 Nov;9(11):e21235
Heliyon 2023 Nov;9(11):e21235
Grape seed proanthocyanidins regulate mitophagy of endothelial cells and promote wound healing in mice through p-JNK/FOXO3a/ROS signal pathway.
Chen L, Hao L, Yanshuo C, FangFang W, Daqin C, Weidong X, Jian X, Shaodong C, Hongyu Z, Ke X
Archives of biochemistry and biophysics 2023 Nov;749:109790
Archives of biochemistry and biophysics 2023 Nov;749:109790
PINK1-mediated mitophagy reduced inflammatory responses to Porphyromonas gingivalis in macrophages.
Jiang K, Li J, Jiang L, Li H, Lei L
Oral diseases 2023 Nov;29(8):3665-3676
Oral diseases 2023 Nov;29(8):3665-3676
Acid ground nano-realgar processed product inhibits breast cancer by inducing mitophagy via the p53/BNIP3/NIX pathway.
Fang J, Zou X, Gong L, Xi J, Liu Y, Yang X, Zhang X, Gui C
Journal of cellular and molecular medicine 2023 Nov;27(22):3478-3490
Journal of cellular and molecular medicine 2023 Nov;27(22):3478-3490
Miquelianin in Folium Nelumbinis extract promotes white-to-beige fat conversion via blocking AMPK/DRP1/mitophagy and modulating gut microbiota in HFD-fed mice.
Wang Z, Yang T, Zeng M, Wang Z, Chen Q, Chen J, Christian M, He Z
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Nov;181:114089
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Nov;181:114089
Melatonin exerts a protective effect in ameliorating nephrolithiasis via targeting AMPK/PINK1-Parkin mediated mitophagy and inhibiting ferroptosis in vivo and in vitro.
Zhou J, Meng L, He Z, Song Q, Liu J, Su X, Wang C, Ke H, Dong C, Liao W, Yang S
International immunopharmacology 2023 Nov;124(Pt A):110801
International immunopharmacology 2023 Nov;124(Pt A):110801
FGD5-AS1/miR-5590-3p/PINK1 induces Lenvatinib resistance in hepatocellular carcinoma.
Song M, Ma L, Shen C, Liu W, Zhang P, Bi R, Zhao C
Cellular signalling 2023 Nov;111:110828
Cellular signalling 2023 Nov;111:110828
Sulforaphane ameliorated podocyte injury according to regulation of the Nrf2/PINK1 pathway for mitophagy in diabetic kidney disease.
Wang Y, Xu Y, Wang Q, Guo F, Song Y, Fan X, Shao M, Chen D, Zhang W, Qin G
European journal of pharmacology 2023 Nov 5;958:176042
European journal of pharmacology 2023 Nov 5;958:176042
Liver metabolomics reveals potential mechanism of Jieduan-Niwan formula against acute-on-chronic liver failure (ACLF) by improving mitochondrial damage and TCA cycle.
Liang J, Wei X, Hou W, Wang H, Ma R, Gao Y, Du Y, Zhang Q
Chinese medicine 2023 Nov 30;18(1):157
Chinese medicine 2023 Nov 30;18(1):157
Extracellular vesicle-derived silk fibroin nanoparticles loaded with MFGE8 accelerate skin ulcer healing by targeting the vascular endothelial cells.
Luo L, Zhang H, Zhang S, Luo C, Kan X, Lv J, Zhao P, Tian Z, Li C
Journal of nanobiotechnology 2023 Nov 29;21(1):455
Journal of nanobiotechnology 2023 Nov 29;21(1):455
ACO2 deficiency increases vulnerability to Parkinson's disease via dysregulating mitochondrial function and histone acetylation-mediated transcription of autophagy genes.
Zhu J, Xu F, Lai H, Yuan H, Li XY, Hu J, Li W, Liu L, Wang C
Communications biology 2023 Nov 25;6(1):1201
Communications biology 2023 Nov 25;6(1):1201
Shenlian extract decreases mitochondrial autophagy to regulate mitochondrial function in microvascular to alleviate coronary artery no-reflow.
Li JJ, Wang YJ, Wang CM, Li YJ, Yang Q, Cai WY, Chen Y, Zhu XX
Phytotherapy research : PTR 2023 May;37(5):1864-1882
Phytotherapy research : PTR 2023 May;37(5):1864-1882
Wei-Tong-Xin ameliorated cisplatin-induced mitophagy and apoptosis in gastric antral mucosa by activating the Nrf2/HO-1 pathway.
Zhang X, Wang S, Jin Y, Wang J, Wang R, Yang X, Zhang S, Yan T, Jia Y
Journal of ethnopharmacology 2023 May 23;308:116253
Journal of ethnopharmacology 2023 May 23;308:116253
Metrnl Alleviates Lipid Accumulation by Modulating Mitochondrial Homeostasis in Diabetic Nephropathy.
Zhou Y, Liu L, Jin B, Wu Y, Xu L, Chang X, Hu L, Wang G, Huang Y, Song L, Zhang T, Wang Y, Xiao Y, Zhang F, Shi M, Liu L, Wang T, Yan R, Guo B
Diabetes 2023 May 1;72(5):611-626
Diabetes 2023 May 1;72(5):611-626
NSC228155 alleviates septic cardiomyopathy via protecting mitochondria and inhibiting inflammation.
Jiang Y, Li Y, Zhang Y, Hu D, Zhang S, Wang C, Huang S, Zhang A, Jia Z, You R
International immunopharmacology 2023 Mar;116:109847
International immunopharmacology 2023 Mar;116:109847
HC067047 as a potent TRPV4 inhibitor repairs endotoxemia colonic injury.
Chen L, Mao M, Liu D, Liu W, Wang Y, Xie L, Deng Y, Lin Y, Xu Y, Zhong X, Cao W
International immunopharmacology 2023 Mar;116:109648
International immunopharmacology 2023 Mar;116:109648
MCU Upregulation Overactivates Mitophagy by Promoting VDAC1 Dimerization and Ubiquitination in the Hepatotoxicity of Cadmium.
Liu C, Li HJ, Duan WX, Duan Y, Yu Q, Zhang T, Sun YP, Li YY, Liu YS, Xu SC
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Mar;10(7):e2203869
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Mar;10(7):e2203869
Berberine Rescues D-Ribose-Induced Alzheimer's Pathology via Promoting Mitophagy.
Wang C, Zou Q, Pu Y, Cai Z, Tang Y
International journal of molecular sciences 2023 Mar 20;24(6)
International journal of molecular sciences 2023 Mar 20;24(6)
MFN1 augmentation prevents retinal degeneration in a Charcot-Marie-Tooth type 2A mouse model.
Shahin S, Lu B, Zhou Y, Xu H, Chetsawang J, Baloh RH, Wang S
iScience 2023 Mar 17;26(3):106270
iScience 2023 Mar 17;26(3):106270
Impaired mitophagy causes mitochondrial DNA leakage and STING activation in ultraviolet B-irradiated human keratinocytes HaCaT.
Li C, Zhu Y, Liu W, Xiang W, He S, Hayashi T, Mizuno K, Hattori S, Fujisaki H, Ikejima T
Archives of biochemistry and biophysics 2023 Mar 15;737:109553
Archives of biochemistry and biophysics 2023 Mar 15;737:109553
Zinc deficiency compromises the maturational competence of porcine oocyte by inducing mitophagy and apoptosis.
Lai XL, Xiong WJ, Li LS, Lan MF, Zhang JX, Zhou YT, Niu D, Duan X
Ecotoxicology and environmental safety 2023 Mar 1;252:114593
Ecotoxicology and environmental safety 2023 Mar 1;252:114593
The physiological metabolite α-ketoglutarate ameliorates osteoarthritis by regulating mitophagy and oxidative stress.
Liu L, Zhang W, Liu T, Tan Y, Chen C, Zhao J, Geng H, Ma C
Redox biology 2023 Jun;62:102663
Redox biology 2023 Jun;62:102663
Naringin regulates endoplasmic reticulum stress and mitophagy through the ATF3/PINK1 signaling axis to alleviate pulmonary fibrosis.
Wei Y, Sun L, Liu C, Li L
Naunyn-Schmiedeberg's archives of pharmacology 2023 Jun;396(6):1155-1169
Naunyn-Schmiedeberg's archives of pharmacology 2023 Jun;396(6):1155-1169
MAGL regulates synovial macrophage polarization vis inhibition of mitophagy in osteoarthritic pain.
Gu C, Chen M, Li X, Geng D, Wang C
Molecular medicine reports 2023 Jun;27(6)
Molecular medicine reports 2023 Jun;27(6)
Neuro death through autophagy via the acetylation of FoxO1 by SIRT2 in the hippocampus of mice in a autism spectrum disorder mice model.
Guo L, Jiang ZM, Zhan YJ, Pan W, Wu QW, Song FX, Zhou X, Zhou XY, Liu LJ, Wang JT
Journal of cellular physiology 2023 Jun;238(6):1275-1287
Journal of cellular physiology 2023 Jun;238(6):1275-1287
DBP induced autophagy and necrotic apoptosis in HepG2 cells via the mitochondrial damage pathway.
Liu H, Xu L, Zhou L, Han W, Li Z, Liu C
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jun;176:113782
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jun;176:113782
A copper complex that combats triple negative breast cancer by restraining angiogenesis.
Zheng H, Hu C, Quan Y, Ye X, Shi X, Guo Z, Wang X
Dalton transactions (Cambridge, England : 2003) 2023 Jun 6;52(22):7626-7634
Dalton transactions (Cambridge, England : 2003) 2023 Jun 6;52(22):7626-7634
Overexpression of fatty acid synthase attenuates bleomycin induced lung fibrosis by restoring mitochondrial dysfunction in mice.
Shin H, Park S, Hong J, Baek AR, Lee J, Kim DJ, Jang AS, Chin SS, Jeong SH, Park SW
Scientific reports 2023 Jun 3;13(1):9044
Scientific reports 2023 Jun 3;13(1):9044
Klotho enhances bone regenerative function of hPDLSCs via modulating immunoregulatory function and cell autophagy.
Niu Q, Chen H, Ou Q, Yang S, Peng Y, Xie Y, Yu L, Cheng Z, Cao Y, Wang Y
Journal of orthopaedic surgery and research 2023 Jun 2;18(1):400
Journal of orthopaedic surgery and research 2023 Jun 2;18(1):400
Radiation resistance of cancer cells caused by mitochondrial dysfunction depends on SIRT3-mediated mitophagy.
Wei Y, Xiao G, Xu H, Sun X, Shi Y, Wang F, Kang J, Peng J, Zhou F
The FEBS journal 2023 Jul;290(14):3629-3645
The FEBS journal 2023 Jul;290(14):3629-3645
Paeoniflorin suppresses kidney inflammation by regulating macrophage polarization via KLF4-mediated mitophagy.
Cao Y, Xiong J, Guan X, Yin S, Chen J, Yuan S, Liu H, Lin S, Zhou Y, Qiu J, Wang D, Liu B, Zhou J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jul 25;116:154901
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jul 25;116:154901
Mechanical force induces mitophagy-mediated anaerobic oxidation in periodontal ligament stem cells.
Zhang Z, Cui S, Fu Y, Wang J, Liu J, Wei F
Cellular & molecular biology letters 2023 Jul 21;28(1):57
Cellular & molecular biology letters 2023 Jul 21;28(1):57
Silibinin alleviates ferroptosis of rat islet β cell INS-1 induced by the treatment with palmitic acid and high glucose through enhancing PINK1/parkin-mediated mitophagy.
Du Q, Wu X, Ma K, Liu W, Liu P, Hayashi T, Mizuno K, Hattori S, Fujisaki H, Ikejima T
Archives of biochemistry and biophysics 2023 Jul 15;743:109644
Archives of biochemistry and biophysics 2023 Jul 15;743:109644
S-Doped carbonized polymer dots inhibit early myocardial fibrosis by regulating mitochondrial function.
Wang Y, Yang M, Zhang J, Ren J, Liu N, Liu B, Lu L, Yang B
Biomaterials science 2023 Jan 31;11(3):894-907
Biomaterials science 2023 Jan 31;11(3):894-907
Electroacupuncture ameliorates surgery-induced spatial memory deficits by promoting mitophagy in rats.
Guo J, Niu K, Ma BF, Sun LN, Fang QW, An JX
Annals of translational medicine 2023 Jan 31;11(2):74
Annals of translational medicine 2023 Jan 31;11(2):74
Multi-Targeting Intranasal Nanoformulation as a Therapeutic for Alzheimer's Disease.
Fihurka O, Wang Y, Hong Y, Lin X, Shen N, Yang H, Brown B, Mommer M, Zieneldien T, Li Y, Kim J, Li M, Cai J, Zhou Q, Cao C
Biomolecules 2023 Jan 25;13(2)
Biomolecules 2023 Jan 25;13(2)
CXCR3 Inhibition Blocks the NF-κB Signaling Pathway by Elevating Autophagy to Ameliorate Lipopolysaccharide-Induced Intestinal Dysfunction in Mice.
Zhang C, Deng Y, Zhang Y, Ba T, Niu S, Chen Y, Gao Y, Dai H
Cells 2023 Jan 1;12(1)
Cells 2023 Jan 1;12(1)
Placental Mesenchymal Stem Cells Alleviate Podocyte Injury in Diabetic Kidney Disease by Modulating Mitophagy via the SIRT1-PGC-1alpha-TFAM Pathway.
Han X, Wang J, Li R, Huang M, Yue G, Guan L, Deng Y, Cai W, Xu J
International journal of molecular sciences 2023 Feb 28;24(5)
International journal of molecular sciences 2023 Feb 28;24(5)
Conjugation of Macrophage-Mimetic Microalgae and Liposome for Antitumor Sonodynamic Immunotherapy via Hypoxia Alleviation and Autophagy Inhibition.
Gao C, Kwong CHT, Wang Q, Kam H, Xie B, Lee SM, Chen G, Wang R
ACS nano 2023 Feb 28;17(4):4034-4049
ACS nano 2023 Feb 28;17(4):4034-4049
Stomatin-like protein 2 deficiency exacerbates adverse cardiac remodeling.
Hu Y, Jiang H, Xu Y, Chen G, Fan R, Zhou Y, Liu Y, Yao Y, Liu R, Chen W, Zhang K, Chen X, Wang R, Qiu Z
Cell death discovery 2023 Feb 14;9(1):63
Cell death discovery 2023 Feb 14;9(1):63
MLKL deficiency attenuated hepatocyte oxidative DNA damage by activating mitophagy to suppress macrophage cGAS-STING signaling during liver ischemia and reperfusion injury.
Xu J, Wu D, Zhou S, Hu H, Li F, Guan Z, Zhan X, Gao Y, Wang P, Rao Z
Cell death discovery 2023 Feb 10;9(1):58
Cell death discovery 2023 Feb 10;9(1):58
Zinc Overload Induces Damage to H9c2 Cardiomyocyte Through Mitochondrial Dysfunction and ROS-Mediated Mitophagy.
Yang Y, Wang P, Guo J, Ma T, Hu Y, Huang L, Xing B, He Y, Xi J
Cardiovascular toxicology 2023 Dec;23(11-12):388-405
Cardiovascular toxicology 2023 Dec;23(11-12):388-405
Stimulator of interferon genes promotes diabetic sarcopenia by targeting peroxisome proliferator activated receptors γ degradation and inhibiting fatty acid oxidation.
Yan SB, Liang H, Zhan P, Zheng H, Zhao QX, Zheng ZJ, Lu HX, Shang GK, Ji XP
Journal of cachexia, sarcopenia and muscle 2023 Dec;14(6):2623-2641
Journal of cachexia, sarcopenia and muscle 2023 Dec;14(6):2623-2641
Ginsenoside Rb1 protects hippocampal neurons in depressed rats based on mitophagy-regulated astrocytic pyroptosis.
Li Y, Li J, Yang L, Ren F, Dong K, Zhao Z, Duan W, Wei W, Guo R
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Dec;121:155083
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Dec;121:155083
Effects of dapagliflozin monotherapy and combined aerobic exercise on skeletal muscle mitochondrial quality control and insulin resistance in type 2 diabetes mellitus rats.
Zhang L, Lin H, Yang X, Shi J, Sheng X, Wang L, Li T, Quan H, Zhai X, Li W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec 31;169:115852
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec 31;169:115852
Neuronal-specific TNFAIP1 ablation attenuates postoperative cognitive dysfunction via targeting SNAP25 for K48-linked ubiquitination.
Wang W, Gao W, Gong P, Song W, Bu X, Hou J, Zhang L, Zhao B
Cell communication and signaling : CCS 2023 Dec 15;21(1):356
Cell communication and signaling : CCS 2023 Dec 15;21(1):356
Mitophagy-dependent cardioprotection of resistance training on heart failure.
Guo C, Wu RY, Dou JH, Song SF, Sun XL, Hu YW, Guo FS, Wei J, Lin L, Wei J
Journal of applied physiology (Bethesda, Md. : 1985) 2023 Dec 1;135(6):1390-1401
Journal of applied physiology (Bethesda, Md. : 1985) 2023 Dec 1;135(6):1390-1401
Zinc oxide nanoparticles induce toxicity in diffuse large B-cell lymphoma cell line U2932 via activating PINK1/Parkin-mediated mitophagy.
Li Z, Yin X, Lyu C, Wang T, Wang W, Zhang J, Wang J, Wang Z, Han C, Zhang R, Guo D, Xu R
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Aug;164:114988
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Aug;164:114988
Deficiency of Pink1 promotes the differentiation of Th1 cells.
Mei X, Lei Y, Ouyang L, Zhao M, Lu Q
Molecular immunology 2023 Aug;160:23-31
Molecular immunology 2023 Aug;160:23-31
PPARγ activation suppresses chondrocyte ferroptosis through mitophagy in osteoarthritis.
Xue X, Dai T, Chen J, Xu Y, Yang Z, Huang J, Xu W, Li S, Meng Q
Journal of orthopaedic surgery and research 2023 Aug 24;18(1):620
Journal of orthopaedic surgery and research 2023 Aug 24;18(1):620
Diosgenin Targets CaMKK2 to Alleviate Type II Diabetic Nephropathy through Improving Autophagy, Mitophagy and Mitochondrial Dynamics.
Zhong Y, Jin R, Luo R, Liu J, Ren L, Zhang Y, Shan Z, Peng X
Nutrients 2023 Aug 11;15(16)
Nutrients 2023 Aug 11;15(16)
Loganin alleviated cognitive impairment in 3×Tg-AD mice through promoting mitophagy mediated by optineurin.
Zhou Y, Luo D, Shi J, Yang X, Xu W, Gao W, Guo Y, Zhao Q, Xie X, He Y, Du G, Pang X
Journal of ethnopharmacology 2023 Aug 10;312:116455
Journal of ethnopharmacology 2023 Aug 10;312:116455
CERS6-derived ceramides aggravate kidney fibrosis by inhibiting PINK1-mediated mitophagy in diabetic kidney disease.
Wang X, Song M, Li X, Su C, Yang Y, Wang K, Liu C, Zheng Z, Jia Y, Ren S, Dong W, Chen J, Wang T, Liu L, Guan M, Zhang C, Xue Y
American journal of physiology. Cell physiology 2023 Aug 1;325(2):C538-C549
American journal of physiology. Cell physiology 2023 Aug 1;325(2):C538-C549
The effect of PINK1/Parkin pathway on glucose homeostasis imbalance induced by tacrolimus in mouse livers.
Li Z, Xiang J, Mei S, Wu Y, Xu Y
Heliyon 2023 Apr;9(4):e15536
Heliyon 2023 Apr;9(4):e15536
Study of the mechanism underlying the role of PINK1/Parkin in the formic acid-induced autophagy of PC12 cells.
Chen N, Yan J, Hu Y, Hao L, Liu H, Yang H
Basic & clinical pharmacology & toxicology 2023 Apr;132(4):329-342
Basic & clinical pharmacology & toxicology 2023 Apr;132(4):329-342
ATG2B upregulated in LPS-stimulated BMSCs-derived exosomes attenuates septic liver injury by inhibiting macrophage STING signaling.
Liu J, Tang M, Li Q, Li Q, Dai Y, Zhou H
International immunopharmacology 2023 Apr;117:109931
International immunopharmacology 2023 Apr;117:109931
TOM complex-independent transport pathway of myoglobin into mitochondria in C2C12 myotubes.
Koma R, Shibaguchi T, Araiso Y, Yamada T, Nonaka Y, Jue T, Masuda K
Physiological reports 2023 Apr;11(7):e15632
Physiological reports 2023 Apr;11(7):e15632
Inhibition of PINK1-Mediated Mitophagy Contributes to Postoperative Cognitive Dysfunction through Activation of Caspase-3/GSDME-Dependent Pyroptosis.
Wang W, Zhao B, Gao W, Song W, Hou J, Zhang L, Xia Z
ACS chemical neuroscience 2023 Apr 5;14(7):1249-1260
ACS chemical neuroscience 2023 Apr 5;14(7):1249-1260
Ginsenoside Rb1 alleviated concanavalin A-induced hepatocyte pyroptosis by activating mitophagy.
Zhang Q, Hu J, Mao A, Liu M, Guan S, Lu J
Food & function 2023 Apr 24;14(8):3793-3803
Food & function 2023 Apr 24;14(8):3793-3803
PRKAA1 induces aberrant mitophagy in a PINK1/Parkin-dependent manner, contributing to fluoride-induced developmental neurotoxicity.
Tang Y, Zhang J, Hu Z, Xu W, Xu P, Ma Y, Xing H, Niu Q
Ecotoxicology and environmental safety 2023 Apr 15;255:114772
Ecotoxicology and environmental safety 2023 Apr 15;255:114772
Melatonin ameliorates glyphosate- and hard water-induced renal tubular epithelial cell senescence via PINK1-Parkin-dependent mitophagy.
Zhang L, Ding F, Wu X, Wang R, Wan Y, Hu J, Zhang X, Wu Q
Ecotoxicology and environmental safety 2023 Apr 15;255:114719
Ecotoxicology and environmental safety 2023 Apr 15;255:114719
Effects of short-term endurance and strength exercise in the molecular regulation of skeletal muscle in hyperinsulinemic and hyperglycemic Slc2a4(+/-) mice.
Muñoz VR, Botezelli JD, Gaspar RC, da Rocha AL, Vieira RFL, Crisol BM, Braga RR, Severino MB, Nakandakari SCBR, Antunes GC, Brunetto SQ, Ramos CD, Velloso LA, Simabuco FM, de Moura LP, da Silva ASR, Ropelle ER, Cintra DE, Pauli JR
Cellular and molecular life sciences : CMLS 2023 Apr 13;80(5):122
Cellular and molecular life sciences : CMLS 2023 Apr 13;80(5):122
MTMR14 Alleviates Chronic Obstructive Pulmonary Disease as a Regulator in Inflammation and Emphysema.
Gu Y, Chen J, Huang Q, Zhan Y, Wang T, Wu J, Zhao J, Zeng Z, Lv Y, Xiao C, Xie J
Oxidative medicine and cellular longevity 2022;2022:9300269
Oxidative medicine and cellular longevity 2022;2022:9300269
Astragaloside IV Protects Detrusor from Partial Bladder Outlet Obstruction-Induced Oxidative Stress by Activating Mitophagy through AMPK-ULK1 Pathway.
Zhu X, Tao F, Zhang L, Yu Y, Xu Y, Yang G, Wei Z, Cheng Y, Yin X, Zhang X, Wei W, Wang A
Oxidative medicine and cellular longevity 2022;2022:5757367
Oxidative medicine and cellular longevity 2022;2022:5757367
Xuesaitong Combined with Dexmedetomidine Improves Cerebral Ischemia-Reperfusion Injury in Rats by Activating Keap1/Nrf2 Signaling and Mitophagy in Hippocampal Tissue.
Han GJ, Min XZ, Ma SS, Ding C, Wang XQ
Oxidative medicine and cellular longevity 2022;2022:5126042
Oxidative medicine and cellular longevity 2022;2022:5126042
Astrocytic IGF-1 and IGF-1R Orchestrate Mitophagy in Traumatic Brain Injury via Exosomal miR-let-7e.
Dabin R, Wei C, Liang S, Ke C, Zhihan W, Ping Z
Oxidative medicine and cellular longevity 2022;2022:3504279
Oxidative medicine and cellular longevity 2022;2022:3504279
Transcutaneous Electrical Acupoint Stimulation Ameliorates Cognitive Function through PINK1/Parkin Mediated Mitophagy in VD Rats.
Hu Z, Wen T, Hu K, Wang R, Su X, Ouyang W, Zhou J, Wen Y
Evidence-based complementary and alternative medicine : eCAM 2022;2022:2810794
Evidence-based complementary and alternative medicine : eCAM 2022;2022:2810794
San-Huang-Yi-Shen Capsule Ameliorates Diabetic Kidney Disease through Inducing PINK1/Parkin-Mediated Mitophagy and Inhibiting the Activation of NLRP3 Signaling Pathway.
Li H, Wang Y, Su X, Wang Q, Zhang S, Sun W, Zhang T, Dong M, Zhang Z, Lv S
Journal of diabetes research 2022;2022:2640209
Journal of diabetes research 2022;2022:2640209
Maltol Promotes Mitophagy and Inhibits Oxidative Stress via the Nrf2/PINK1/Parkin Pathway after Spinal Cord Injury.
Mao Y, Du J, Chen X, Al Mamun A, Cao L, Yang Y, Mubwandarikwa J, Zaeem M, Zhang W, Chen Y, Dai Y, Xiao J, Ye K
Oxidative medicine and cellular longevity 2022;2022:1337630
Oxidative medicine and cellular longevity 2022;2022:1337630
The inhibition of PGAM5 suppresses seizures in a kainate-induced epilepsy model via mitophagy reduction.
Zhong F, Gan Y, Song J, Zhang W, Yuan S, Qin Z, Wu J, Lü Y, Yu W
Frontiers in molecular neuroscience 2022;15:1047801
Frontiers in molecular neuroscience 2022;15:1047801
Ginkgolide B Protects Against Ischemic Stroke via Targeting AMPK/PINK1.
Cao Y, Yang L, Cheng H
Frontiers in pharmacology 2022;13:941094
Frontiers in pharmacology 2022;13:941094
Reduced Immunity Regulator MAVS Contributes to Non-Hypertrophic Cardiac Dysfunction by Disturbing Energy Metabolism and Mitochondrial Homeostasis.
Wang Q, Sun Z, Cao S, Lin X, Wu M, Li Y, Yin J, Zhou W, Huang S, Zhang A, Zhang Y, Xia W, Jia Z
Frontiers in immunology 2022;13:919038
Frontiers in immunology 2022;13:919038
Heat Shock Transcription Factor 2 Promotes Mitophagy of Intestinal Epithelial Cells Through PARL/PINK1/Parkin Pathway in Ulcerative Colitis.
Liang H, Zhang F, Wang W, Zhao W, Zhou J, Feng Y, Wu J, Li M, Bai X, Zeng Z, Niu J, Miao Y
Frontiers in pharmacology 2022;13:893426
Frontiers in pharmacology 2022;13:893426
Number 2 Feibi Recipe Inhibits H(2)O(2)-Mediated Oxidative Stress Damage of Alveolar Epithelial Cells by Regulating the Balance of Mitophagy/Apoptosis.
Gu X, Long Q, Wei W, Tong J, Li Z, Zhang Z, Jiao Y
Frontiers in pharmacology 2022;13:830554
Frontiers in pharmacology 2022;13:830554
Harpagoside Protects Against Doxorubicin-Induced Cardiotoxicity via P53-Parkin-Mediated Mitophagy.
Li W, Wang X, Liu T, Zhang Q, Cao J, Jiang Y, Sun Q, Li C, Wang W, Wang Y
Frontiers in cell and developmental biology 2022;10:813370
Frontiers in cell and developmental biology 2022;10:813370
Restoration of mitophagy ameliorates cardiomyopathy in Barth syndrome.
Zhang J, Liu X, Nie J, Shi Y
Autophagy 2022 Sep;18(9):2134-2149
Autophagy 2022 Sep;18(9):2134-2149
Elevated SFXN2 limits mitochondrial autophagy and increases iron-mediated energy production to promote multiple myeloma cell proliferation.
Chen Y, Qian J, Ding P, Wang W, Li X, Tang X, Tang C, Yang Y, Gu C
Cell death & disease 2022 Sep 26;13(9):822
Cell death & disease 2022 Sep 26;13(9):822
Inhibition of autophagy with chloroquine dysregulates mitochondrial quality control and energetics in adipocytes.
Javaid HMA, Lim H, Shin S, Huh JY
Archives of pharmacal research 2022 Oct;45(10):731-742
Archives of pharmacal research 2022 Oct;45(10):731-742
Comparing the mitochondrial signatures in ESCs and iPSCs and their neural derivations.
Kristiansen CK, Chen A, Høyland LE, Ziegler M, Sullivan GJ, Bindoff LA, Liang KX
Cell cycle (Georgetown, Tex.) 2022 Oct;21(20):2206-2221
Cell cycle (Georgetown, Tex.) 2022 Oct;21(20):2206-2221
Omentin1 ameliorates myocardial ischemia-induced heart failure via SIRT3/FOXO3a-dependent mitochondrial dynamical homeostasis and mitophagy.
Hu J, Liu T, Fu F, Cui Z, Lai Q, Zhang Y, Yu B, Liu F, Kou J, Li F
Journal of translational medicine 2022 Oct 4;20(1):447
Journal of translational medicine 2022 Oct 4;20(1):447
The oncoprotein MUC1 facilitates breast cancer progression by promoting Pink1-dependent mitophagy via ATAD3A destabilization.
Li Q, Chu Y, Li S, Yu L, Deng H, Liao C, Liao X, Yang C, Qi M, Cheng J, Chen G, Huang L
Cell death & disease 2022 Oct 26;13(10):899
Cell death & disease 2022 Oct 26;13(10):899
Mitophagy induced by classical swine fever virus nonstructural protein 5A promotes viral replication.
Chengcheng Z, Xiuling W, Jiahao S, Mengjiao G, Xiaorong Z, Yantao W
Virus research 2022 Oct 15;320:198886
Virus research 2022 Oct 15;320:198886
Anti-ANGPTL3-FLD monoclonal antibody treatment ameliorates podocyte lesions through attenuating mitochondrial damage.
Lv Q, Han X, Ni J, Ma Q, Dai R, Liu J, Liu J, Zhai Y, Shen Q, Sun L, Liu H, Rao J, Xu H
Cell death & disease 2022 Oct 13;13(10):867
Cell death & disease 2022 Oct 13;13(10):867
Effects of ferulic acid, a major component of rice bran, on proliferation, apoptosis, and autophagy of HepG2 cells.
Wang J, Lai X, Yuan D, Liu Y, Wang J, Liang Y
Food research international (Ottawa, Ont.) 2022 Nov;161:111816
Food research international (Ottawa, Ont.) 2022 Nov;161:111816
Cadmium-induced apoptosis of Leydig cells is mediated by excessive mitochondrial fission and inhibition of mitophagy.
Yi L, Shang XJ, Lv L, Wang Y, Zhang J, Quan C, Shi Y, Liu Y, Zhang L
Cell death & disease 2022 Nov 5;13(11):928
Cell death & disease 2022 Nov 5;13(11):928
Salidroside reduces neuropathology in Alzheimer's disease models by targeting NRF2/SIRT3 pathway.
Yao Y, Ren Z, Yang R, Mei Y, Dai Y, Cheng Q, Xu C, Xu X, Wang S, Kim KM, Noh JH, Zhu J, Zhao N, Liu YU, Mao G, Sima J
Cell & bioscience 2022 Nov 4;12(1):180
Cell & bioscience 2022 Nov 4;12(1):180
O-GlcNAcylation of SIRT1 Protects against Cold Stress-Induced Skeletal Muscle Damage via Amelioration of Mitochondrial Homeostasis.
Cao Y, Zhang M, Li Y, Lu J, Zhou W, Li X, Shi H, Xu B, Li S
International journal of molecular sciences 2022 Nov 22;23(23)
International journal of molecular sciences 2022 Nov 22;23(23)
Effective-component compatibility of Bufei Yishen formula III ameliorated COPD by improving airway epithelial cell senescence by promoting mitophagy via the NRF2/PINK1 pathway.
Li MY, Qin YQ, Tian YG, Li KC, Oliver BG, Liu XF, Zhao P, Li JS
BMC pulmonary medicine 2022 Nov 22;22(1):434
BMC pulmonary medicine 2022 Nov 22;22(1):434
Inhibition of human peptide deformylase by actinonin sensitizes glioblastoma cells to temozolomide chemotherapy.
Lan B, Zhao H, He Y, Zhao Z, Wang N, Gao Y
Experimental cell research 2022 Nov 15;420(2):113358
Experimental cell research 2022 Nov 15;420(2):113358
Repeated social defeat stress inhibits development of hippocampus neurons through mitophagy and autophagy.
Guo L, Jiang ZM, Sun RX, Pang W, Zhou X, Du ML, Chen MX, Lv X, Wang JT
Brain research bulletin 2022 May;182:111-117
Brain research bulletin 2022 May;182:111-117
Dl-3-n-butylphthalide attenuates myocardial ischemia reperfusion injury by suppressing oxidative stress and regulating cardiac mitophagy via the PINK1/Parkin pathway in rats.
Zhang D, Zheng N, Fu X, Shi J, Zhang J
Journal of thoracic disease 2022 May;14(5):1651-1662
Journal of thoracic disease 2022 May;14(5):1651-1662
Ivermectin-Induced Apoptotic Cell Death in Human SH-SY5Y Cells Involves the Activation of Oxidative Stress and Mitochondrial Pathway and Akt/mTOR-Pathway-Mediated Autophagy.
Zhang Y, Sun T, Li M, Lin Y, Liu Y, Tang S, Dai C
Antioxidants (Basel, Switzerland) 2022 May 5;11(5)
Antioxidants (Basel, Switzerland) 2022 May 5;11(5)
Apigenin alleviated PA-induced pyroptosis by activating autophagy in hepatocytes.
Meng Z, Zhu B, Gao M, Wang G, Zhou H, Lu J, Guan S
Food & function 2022 May 23;13(10):5559-5570
Food & function 2022 May 23;13(10):5559-5570
Cardioprotective effect of ginsenoside Rb1 via regulating metabolomics profiling and AMP-activated protein kinase-dependent mitophagy.
Hu J, Zhang L, Fu F, Lai Q, Zhang L, Liu T, Yu B, Kou J, Li F
Journal of ginseng research 2022 Mar;46(2):255-265
Journal of ginseng research 2022 Mar;46(2):255-265
Maintaining homeostasis of mitochondria and endoplasmic reticulum with NSC228155 alleviates cisplatin-induced acute kidney injury.
Li Y, Jiang Y, Zhou W, Wu Y, Zhang S, Ding G, Zhang Y, Zhang A, Huang S, Jia Z, You R
Free radical biology & medicine 2022 Mar;181:270-287
Free radical biology & medicine 2022 Mar;181:270-287
PINK1 regulates mitochondrial fission/fusion and neuroinflammation in β-amyloid-induced Alzheimer's disease models.
Wang X, Xue Y, Yao Y, Li Y, Ji X, Chi T, Liu P, Zou L
Neurochemistry international 2022 Mar;154:105298
Neurochemistry international 2022 Mar;154:105298
Involvement of NEAT1/PINK1-mediated mitophagy in chronic obstructive pulmonary disease induced by cigarette smoke or PM(2.5).
Lin Q, Zhang CF, Guo JL, Su JL, Guo ZK, Li HY
Annals of translational medicine 2022 Mar;10(6):277
Annals of translational medicine 2022 Mar;10(6):277
Chicoric Acid Attenuated Renal Tubular Injury in HFD-Induced Chronic Kidney Disease Mice through the Promotion of Mitophagy via the Nrf2/PINK/Parkin Pathway.
Ding XQ, Jian TY, Gai YN, Niu GT, Liu Y, Meng XH, Li J, Lyu H, Ren BR, Chen J
Journal of agricultural and food chemistry 2022 Mar 9;70(9):2923-2935
Journal of agricultural and food chemistry 2022 Mar 9;70(9):2923-2935
Dioscin relieves diabetic nephropathy via suppressing oxidative stress and apoptosis, and improving mitochondrial quality and quantity control.
Zhong Y, Liu J, Sun D, Guo T, Yao Y, Xia X, Shi C, Peng X
Food & function 2022 Mar 21;13(6):3660-3673
Food & function 2022 Mar 21;13(6):3660-3673
Mitophagy induced by UMI-77 preserves mitochondrial fitness in renal tubular epithelial cells and alleviates renal fibrosis.
Jin L, Yu B, Liu G, Nie W, Wang J, Chen J, Xiao L, Xia H, Han F, Yang Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Jun;36(6):e22342
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Jun;36(6):e22342
A novel PHD2 inhibitor acteoside from Cistanche tubulosa induces skeletal muscle mitophagy to improve cancer-related fatigue.
Zhang S, Gong F, Liu J, Liu T, Yang J, Hu J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Jun;150:113004
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Jun;150:113004
Exercise training improves cardiac function and regulates myocardial mitophagy differently in ischaemic and pressure-overload heart failure mice.
Guo C, Chen MJ, Zhao JR, Wu RY, Zhang Y, Li QQ, Zhao H, Dou JH, Song SF, Wei J
Experimental physiology 2022 Jun;107(6):562-574
Experimental physiology 2022 Jun;107(6):562-574
Transcription factor nuclear factor erythroid 2 p45-related factor 2 (NRF2) ameliorates sepsis-associated acute kidney injury by maintaining mitochondrial homeostasis and improving the mitochondrial function.
Chen Z, Wang H, Hu B, Chen X, Zheng M, Liang L, Lyu J, Zeng Q
European journal of histochemistry : EJH 2022 Jun 21;66(3)
European journal of histochemistry : EJH 2022 Jun 21;66(3)
Oxidative stress from DGAT1 oncoprotein inhibition in melanoma suppresses tumor growth when ROS defenses are also breached.
Wilcock DJ, Badrock AP, Wong CW, Owen R, Guerin M, Southam AD, Johnston H, Telfer BA, Fullwood P, Watson J, Ferguson H, Ferguson J, Lloyd GR, Jankevics A, Dunn WB, Wellbrock C, Lorigan P, Ceol C, Francavilla C, Smith MP, Hurlstone AFL
Cell reports 2022 Jun 21;39(12):110995
Cell reports 2022 Jun 21;39(12):110995
Integrated metabolism and epigenetic modifications in the macrophages of mice in responses to cold stress.
Lu J, Fu S, Dai J, Hu J, Li S, Ji H, Wang Z, Yu J, Bao J, Xu B, Guo J, Yang H
Journal of Zhejiang University. Science. B 2022 Jun 15;23(6):461-480
Journal of Zhejiang University. Science. B 2022 Jun 15;23(6):461-480
Ophiopogonin D'-induced mitophagy and mitochondrial damage are associated with dysregulation of the PINK1/Parkin signaling pathway in AC16 cells.
Lei S, Feng Y, Huang P, Chen B, Bao K, Wu Q, Zhang H, Huang X
Toxicology 2022 Jul;477:153275
Toxicology 2022 Jul;477:153275
Effects of Wenyang Zhenshuai Granules on the Expression of Key Mitochondrial Autophagy Proteins in the Doxorubicin-Induced Model of H9c2 Cardiomyocyte Injury.
Peng LQ, Wu XX, Chen G, Cai HZ, Tang YP, Chen QY, Chen XY
Bulletin of experimental biology and medicine 2022 Jul;173(3):335-340
Bulletin of experimental biology and medicine 2022 Jul;173(3):335-340
Resveratrol alleviates enterotoxigenic Escherichia coli K88-induced damage by regulating SIRT-1 signaling in intestinal porcine epithelial cells.
Luo X, Wu S, Jia H, Si X, Song Z, Zhai Z, Bai J, Li J, Yang Y, Wu Z
Food & function 2022 Jul 4;13(13):7346-7360
Food & function 2022 Jul 4;13(13):7346-7360
Jujuboside A ameliorates high fat diet and streptozotocin induced diabetic nephropathy via suppressing oxidative stress, apoptosis, and enhancing autophagy.
Zhong Y, Luo R, Liu Q, Zhu J, Lei M, Liang X, Wang X, Peng X
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2022 Jan;159:112697
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2022 Jan;159:112697
Bombyx mori cypovirus (BmCPV) induces PINK1-Parkin mediated mitophagy via interaction of VP4 with host Tom40.
Zhu M, Pan J, Zhang M, Tong X, Zhang Y, Zhang Z, Liang Z, Zhang X, Hu X, Xue R, Cao G, Gong C
Developmental and comparative immunology 2022 Jan;126:104244
Developmental and comparative immunology 2022 Jan;126:104244
Interfering with mitochondrial dynamics sensitizes glioblastoma multiforme to temozolomide chemotherapy.
Wang N, Huang R, Yang K, He Y, Gao Y, Dong D
Journal of cellular and molecular medicine 2022 Feb;26(3):893-912
Journal of cellular and molecular medicine 2022 Feb;26(3):893-912
Deoxyhypusine hydroxylase as a novel pharmacological target for ischemic stroke via inducing a unique post-translational hypusination modification.
Guo Q, Zhang YC, Wang W, Wang YQ, Liu Y, Yang Z, Zhao MM, Feng N, Wang YH, Zhang XW, Yang H, Liu TT, Shi LY, Shi XM, Liu D, Tu PF, Zeng KW
Pharmacological research 2022 Feb;176:106046
Pharmacological research 2022 Feb;176:106046
Salvianolic acid B alleviates diabetic endothelial and mitochondrial dysfunction by down-regulating apoptosis and mitophagy of endothelial cells.
Xiang J, Zhang C, Di T, Chen L, Zhao W, Wei L, Zhou S, Wu X, Wang G, Zhang Y
Bioengineered 2022 Feb;13(2):3486-3502
Bioengineered 2022 Feb;13(2):3486-3502
Tourniquet-induced lower limb ischemia/reperfusion reduces mitochondrial function by decreasing mitochondrial biogenesis in acute kidney injury in mice.
Packialakshmi B, Stewart IJ, Burmeister DM, Feng Y, McDaniel DP, Chung KK, Zhou X
Physiological reports 2022 Feb;10(3):e15181
Physiological reports 2022 Feb;10(3):e15181
Disuse-associated loss of the protease LONP1 in muscle impairs mitochondrial function and causes reduced skeletal muscle mass and strength.
Xu Z, Fu T, Guo Q, Zhou D, Sun W, Zhou Z, Chen X, Zhang J, Liu L, Xiao L, Yin Y, Jia Y, Pang E, Chen Y, Pan X, Fang L, Zhu MS, Fei W, Lu B, Gan Z
Nature communications 2022 Feb 16;13(1):894
Nature communications 2022 Feb 16;13(1):894
Mitochondria-Dependent Oxidative Stress Mediates ZnO Nanoparticle (ZnO NP)-Induced Mitophagy and Lipotoxicity in Freshwater Teleost Fish.
Chen GH, Song CC, Zhao T, Hogstrand C, Wei XL, Lv WH, Song YF, Luo Z
Environmental science & technology 2022 Feb 15;56(4):2407-2420
Environmental science & technology 2022 Feb 15;56(4):2407-2420
Nano-graphene oxide depresses neurotransmission by blocking retrograde transport of mitochondria.
Kang Y, Yin S, Liu J, Jiang Y, Huang Z, Chen L, Shao L
Journal of hazardous materials 2022 Feb 15;424(Pt D):127660
Journal of hazardous materials 2022 Feb 15;424(Pt D):127660
Polygala saponins inhibit NLRP3 inflammasome-mediated neuroinflammation via SHP-2-Mediated mitophagy.
Qiu WQ, Ai W, Zhu FD, Zhang Y, Guo MS, Law BY, Wu JM, Wong VK, Tang Y, Yu L, Chen Q, Yu CL, Liu J, Qin DL, Zhou XG, Wu AG
Free radical biology & medicine 2022 Feb 1;179:76-94
Free radical biology & medicine 2022 Feb 1;179:76-94
RNA sequence analysis reveals pathways and candidate genes associated with pancreatic acinar cells injury in a mouse pancreatitis model.
Chaoqun H, Rong Y, Yunpeng P, Xiaole Z, Wanli G, Chenyuan S, Dongya H, Yi M, Qiang L
Tissue & cell 2022 Dec;79:101940
Tissue & cell 2022 Dec;79:101940
Phytosphingosine-induced cell apoptosis via a mitochondrially mediated pathway.
Li J, Wen J, Sun C, Zhou Y, Xu J, MacIsaac HJ, Chang X, Cui Q
Toxicology 2022 Dec;482:153370
Toxicology 2022 Dec;482:153370
The SMYD3-MTHFD1L-formate metabolic regulatory axis mediates mitophagy to inhibit M1 polarization in macrophages.
Zhu W, Wang C, Xue L, Liu L, Yang X, Liu Z, Zhang S, Luo D
International immunopharmacology 2022 Dec;113(Pt A):109352
International immunopharmacology 2022 Dec;113(Pt A):109352
Stomatin-like protein-2 attenuates macrophage pyroptosis and H9c2 cells apoptosis by protecting mitochondrial function.
Fan R, Jiang H, Hu Y, Xu Y, Zhou Y, Chen G, Liu Y, Yao Y, Qin W, Chen W, Huang F, Chen X
Biochemical and biophysical research communications 2022 Dec 25;636(Pt 1):112-120
Biochemical and biophysical research communications 2022 Dec 25;636(Pt 1):112-120
Glucagon-like Peptide 1 Receptor Activation Inhibits Microglial Pyroptosis via Promoting Mitophagy to Alleviate Depression-like Behaviors in Diabetic Mice.
Yang F, Wang X, Qi J, Zhang K, Jiang Y, Feng B, Lv T, Yang L, Yang Q, Zhao M, Liu S, Ma X
Nutrients 2022 Dec 21;15(1)
Nutrients 2022 Dec 21;15(1)
PINK1 overexpression prevents forskolin-induced tau hyperphosphorylation and oxidative stress in a rat model of Alzheimer's disease.
Wang XJ, Qi L, Cheng YF, Ji XF, Chi TY, Liu P, Zou LB
Acta pharmacologica Sinica 2022 Aug;43(8):1916-1927
Acta pharmacologica Sinica 2022 Aug;43(8):1916-1927
CDK9 inhibition blocks the initiation of PINK1-PRKN-mediated mitophagy by regulating the SIRT1-FOXO3-BNIP3 axis and enhances the therapeutic effects involving mitochondrial dysfunction in hepatocellular carcinoma.
Yao J, Wang J, Xu Y, Guo Q, Sun Y, Liu J, Li S, Guo Y, Wei L
Autophagy 2022 Aug;18(8):1879-1897
Autophagy 2022 Aug;18(8):1879-1897
The Degradation of TMEM166 by Autophagy Promotes AMPK Activation to Protect SH-SY5Y Cells Exposed to MPP().
Liao Z, Gong Z, Wang Z, Yang W, Liu W, Hou L, Liu X, Hua J, Wang B, Li N
Cells 2022 Aug 30;11(17)
Cells 2022 Aug 30;11(17)
Development of artesunate intelligent prodrug liposomes based on mitochondrial targeting strategy.
Gu L, Zhang J, Liu D, Chen J, Liu S, Peng Q, Tian Y, Du M, Zhang J, Xiao W, Shen S, Wang J
Journal of nanobiotechnology 2022 Aug 13;20(1):376
Journal of nanobiotechnology 2022 Aug 13;20(1):376
Melatonin Attenuates Ropivacaine-Induced Apoptosis by Inhibiting Excessive Mitophagy Through the Parkin/PINK1 Pathway in PC12 and HT22 Cells.
Zeng L, He J, Liu C, Zhang F, Zhang Z, Chen H, Wang Q, Ding X, Luo H
Inflammation 2022 Apr;45(2):725-738
Inflammation 2022 Apr;45(2):725-738
SIRT2 Is Critical for Sheep Oocyte Maturation through Regulating Function of Surrounding Granulosa Cells.
Fang X, Xia W, Li S, Qi Y, Liu M, Yu Y, Li H, Li M, Tao C, Wang Z, Li J
International journal of molecular sciences 2022 Apr 30;23(9)
International journal of molecular sciences 2022 Apr 30;23(9)
Exercise activates autophagy and regulates endoplasmic reticulum stress in muscle of high-fat diet mice to alleviate insulin resistance.
Cheng F, Dun Y, Cheng J, Ripley-Gonzalez JW, Jiang W, You B, Liu S
Biochemical and biophysical research communications 2022 Apr 23;601:45-51
Biochemical and biophysical research communications 2022 Apr 23;601:45-51
Flubendazole induces mitochondrial dysfunction and DRP1-mediated mitophagy by targeting EVA1A in breast cancer.
Zhen Y, Yuan Z, Zhang J, Chen Y, Fu Y, Liu Y, Fu L, Zhang L, Zhou XL
Cell death & disease 2022 Apr 19;13(4):375
Cell death & disease 2022 Apr 19;13(4):375
Urolithin A promotes mitophagy and suppresses NLRP3 inflammasome activation in lipopolysaccharide-induced BV2 microglial cells and MPTP-induced Parkinson's disease model.
Qiu J, Chen Y, Zhuo J, Zhang L, Liu J, Wang B, Sun D, Yu S, Lou H
Neuropharmacology 2022 Apr 1;207:108963
Neuropharmacology 2022 Apr 1;207:108963
Bhlhe40/Sirt1 Axis-Regulated Mitophagy Is Implicated in All-Trans Retinoic Acid-Induced Spina Bifida Aperta.
Zhao L, Liu D, Ma W, Gu H, Wei X, Luo W, Yuan Z
Frontiers in cell and developmental biology 2021;9:644346
Frontiers in cell and developmental biology 2021;9:644346
Samm50 Promotes Hypertrophy by Regulating Pink1-Dependent Mitophagy Signaling in Neonatal Cardiomyocytes.
Xu R, Kang L, Wei S, Yang C, Fu Y, Ding Z, Zou Y
Frontiers in cardiovascular medicine 2021;8:748156
Frontiers in cardiovascular medicine 2021;8:748156
Knockdown of VDAC1 alleviates the cognitive dysfunction secondary to sepsis-associated encephalopathy.
Cai M, Du B, Si Y, Miao J, Ge J, Zhang J, Song J, Bao H
American journal of translational research 2021;13(7):7538-7555
American journal of translational research 2021;13(7):7538-7555
SARS-CoV-2 Causes Mitochondrial Dysfunction and Mitophagy Impairment.
Shang C, Liu Z, Zhu Y, Lu J, Ge C, Zhang C, Li N, Jin N, Li Y, Tian M, Li X
Frontiers in microbiology 2021;12:780768
Frontiers in microbiology 2021;12:780768
Aldehyde Dehydrogenase 2 Protects Against Lipopolysaccharide-Induced Myocardial Injury by Suppressing Mitophagy.
Ji W, Wan T, Zhang F, Zhu X, Guo S, Mei X
Frontiers in pharmacology 2021;12:641058
Frontiers in pharmacology 2021;12:641058
Astragaloside II Ameliorated Podocyte Injury and Mitochondrial Dysfunction in Streptozotocin-Induced Diabetic Rats.
Su J, Gao C, Xie L, Fan Y, Shen Y, Huang Q, Wang N, Xu Y, Yang N, Gui D
Frontiers in pharmacology 2021;12:638422
Frontiers in pharmacology 2021;12:638422
A Mitochondrial DNA Variant Elevates the Risk of Gallstone Disease by Altering Mitochondrial Function.
Sun D, Niu Z, Zheng HX, Wu F, Jiang L, Han TQ, Wei Y, Wang J, Jin L
Cellular and molecular gastroenterology and hepatology 2021;11(4):1211-1226.e15
Cellular and molecular gastroenterology and hepatology 2021;11(4):1211-1226.e15
HIF-1-induced mitochondrial ribosome protein L52: a mechanism for breast cancer cellular adaptation and metastatic initiation in response to hypoxia.
Li X, Wang M, Li S, Chen Y, Wang M, Wu Z, Sun X, Yao L, Dong H, Song Y, Xu Y
Theranostics 2021;11(15):7337-7359
Theranostics 2021;11(15):7337-7359
Trimetazidine and exercise provide comparable improvements to high fat diet-induced muscle dysfunction through enhancement of mitochondrial quality control.
Zhang W, You B, Qi D, Qiu L, Ripley-Gonzalez JW, Zheng F, Fu S, Li C, Dun Y, Liu S
Scientific reports 2021 Sep 27;11(1):19116
Scientific reports 2021 Sep 27;11(1):19116
The protection of selenium against cadmium-induced mitophagy via modulating nuclear xenobiotic receptors response and oxidative stress in the liver of rabbits.
Zhang L, Yang F, Li Y, Cao H, Huang A, Zhuang Y, Zhang C, Hu G, Mao Y, Luo J, Xing C
Environmental pollution (Barking, Essex : 1987) 2021 Sep 15;285:117301
Environmental pollution (Barking, Essex : 1987) 2021 Sep 15;285:117301
Moderate mechanical stress suppresses the IL-1β-induced chondrocyte apoptosis by regulating mitochondrial dynamics.
Zhang J, Hao X, Chi R, Qi J, Xu T
Journal of cellular physiology 2021 Nov;236(11):7504-7515
Journal of cellular physiology 2021 Nov;236(11):7504-7515
Suppressing TRAP1 sensitizes glioblastoma multiforme cells to temozolomide.
Wang N, Zhu P, Huang R, Sun L, Dong D, Gao Y
Experimental and therapeutic medicine 2021 Nov;22(5):1246
Experimental and therapeutic medicine 2021 Nov;22(5):1246
Maternal selenium deficiency suppresses proliferation, induces autophagy dysfunction and apoptosis in the placenta of mice.
Li M, Cheng W, Zhang L
Metallomics : integrated biometal science 2021 Nov 19;13(11)
Metallomics : integrated biometal science 2021 Nov 19;13(11)
Neurotoxicity of a pyrethroid pesticide deltamethrin is associated with the imbalance in proteolytic systems caused by mitophagy activation and proteasome inhibition.
Hirano T, Suzuki N, Ikenaka Y, Hoshi N, Tabuchi Y
Toxicology and applied pharmacology 2021 Nov 1;430:115723
Toxicology and applied pharmacology 2021 Nov 1;430:115723
Biosynthetic gold nanoparticles of Hibiscus syriacus L. callus potentiates anti-inflammation efficacy via an autophagy-dependent mechanism.
Xu XY, Tran THM, Perumalsamy H, Sanjeevram D, Kim YJ
Materials science & engineering. C, Materials for biological applications 2021 May;124:112035
Materials science & engineering. C, Materials for biological applications 2021 May;124:112035
PINK1 contained in huMSC-derived exosomes prevents cardiomyocyte mitochondrial calcium overload in sepsis via recovery of mitochondrial Ca(2+) efflux.
Zhou Q, Xie M, Zhu J, Yi Q, Tan B, Li Y, Ye L, Zhang X, Zhang Y, Tian J, Xu H
Stem cell research & therapy 2021 May 6;12(1):269
Stem cell research & therapy 2021 May 6;12(1):269
Scutellarin ameliorates high glucose-induced vascular endothelial cells injury by activating PINK1/Parkin-mediated mitophagy.
Xi J, Rong Y, Zhao Z, Huang Y, Wang P, Luan H, Xing Y, Li S, Liao J, Dai Y, Liang J, Wu F
Journal of ethnopharmacology 2021 May 10;271:113855
Journal of ethnopharmacology 2021 May 10;271:113855
Electroacupuncture at GV20‑GB7 regulates mitophagy to protect against neurological deficits following intracerebral hemorrhage via inhibition of apoptosis.
Guan R, Li Z, Dai X, Zou W, Yu X, Liu H, Chen Q, Teng W, Liu P, Liu X, Dong S
Molecular medicine reports 2021 Jul;24(1)
Molecular medicine reports 2021 Jul;24(1)
Autophagy regulates functional differentiation of mammary epithelial cells.
Elswood J, Pearson SJ, Payne HR, Barhoumi R, Rijnkels M, W Porter W
Autophagy 2021 Feb;17(2):420-438
Autophagy 2021 Feb;17(2):420-438
Exercise alters the mitochondrial proteostasis and induces the mitonuclear imbalance and UPR(mt) in the hypothalamus of mice.
Braga RR, Crisol BM, Brícola RS, Sant'ana MR, Nakandakari SCBR, Costa SO, Prada PO, da Silva ASR, Moura LP, Pauli JR, Cintra DE, Ropelle ER
Scientific reports 2021 Feb 15;11(1):3813
Scientific reports 2021 Feb 15;11(1):3813
Dynamic observation of 5-fluorouracil-induced myocardial injury and mitochondrial autophagy in aging rats.
Li Y, Zhang Y, Zhou X, Lei X, Li X, Wei L
Experimental and therapeutic medicine 2021 Dec;22(6):1451
Experimental and therapeutic medicine 2021 Dec;22(6):1451
Citrus alkaline extracts prevent endoplasmic reticulum stress in type II alveolar epithelial cells to ameliorate pulmonary fibrosis via the ATF3/PINK1 pathway.
Wang Z, Feng F, He H, Wu Q, Gu C, Hrovat J, Peng W, Xu Y, Han D, Yang P, Zhou X, Li J, Shan J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Aug;89:153599
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Aug;89:153599
Biosynthesis of gold nanoparticles using Nigella sativa and Curtobacterium proimmune K3 and evaluation of their anticancer activity.
Dhandapani S, Xu X, Wang R, Puja AM, Kim H, Perumalsamy H, Balusamy SR, Kim YJ
Materials science & engineering. C, Materials for biological applications 2021 Aug;127:112214
Materials science & engineering. C, Materials for biological applications 2021 Aug;127:112214
Effects of the Cytoplasm and Mitochondrial Specific Hydroxyl Radical Scavengers TA293 and mitoTA293 in Bleomycin-Induced Pulmonary Fibrosis Model Mice.
Sakai T, Takagaki H, Yamagiwa N, Ui M, Hatta S, Imai J
Antioxidants (Basel, Switzerland) 2021 Aug 31;10(9)
Antioxidants (Basel, Switzerland) 2021 Aug 31;10(9)
An Experimentally Induced Mutation in the UBA Domain of p62 Changes the Sensitivity of Cisplatin by Up-Regulating HK2 Localisation on the Mitochondria and Increasing Mitophagy in A2780 Ovarian Cancer Cells.
Yu S, Yan X, Tian R, Xu L, Zhao Y, Sun L, Su J
International journal of molecular sciences 2021 Apr 13;22(8)
International journal of molecular sciences 2021 Apr 13;22(8)
Mitochondria-targeted magnolol inhibits OXPHOS, proliferation, and tumor growth via modulation of energetics and autophagy in melanoma cells.
Cheng G, Hardy M, Zielonka J, Weh K, Zielonka M, Boyle KA, Abu Eid M, McAllister D, Bennett B, Kresty LA, Dwinell MB, Kalyanaraman B
Cancer treatment and research communications 2020;25:100210
Cancer treatment and research communications 2020;25:100210
Ginseng-Sanqi-Chuanxiong (GSC) Extracts Ameliorate Diabetes-Induced Endothelial Cell Senescence through Regulating Mitophagy via the AMPK Pathway.
Wang X, Zhang JQ, Xiu CK, Yang J, Fang JY, Lei Y
Oxidative medicine and cellular longevity 2020;2020:7151946
Oxidative medicine and cellular longevity 2020;2020:7151946
Bcl-2 Proteins Regulate Mitophagy in Lipopolysaccharide-Induced Acute Lung Injury via PINK1/Parkin Signaling Pathway.
Zhang Z, Chen Z, Liu R, Liang Q, Peng Z, Yin S, Tang J, Gong T, Liu Y
Oxidative medicine and cellular longevity 2020;2020:6579696
Oxidative medicine and cellular longevity 2020;2020:6579696
Deletion of mitochondrial uncoupling protein 2 exacerbates mitophagy and cell apoptosis after cerebral ischemia and reperfusion injury in mice.
He M, Zhang T, Fan Y, Ma Y, Zhang J, Jing L, Li PA
International journal of medical sciences 2020;17(17):2869-2878
International journal of medical sciences 2020;17(17):2869-2878
Chaetomugilin J Enhances Apoptosis in Human Ovarian Cancer A2780 Cells Induced by Cisplatin Through Inhibiting Pink1/Parkin Mediated Mitophagy.
Hu X, Wang J, Chai J, Yu X, Zhang Y, Feng Y, Qin J, Yu H
OncoTargets and therapy 2020;13:9967-9976
OncoTargets and therapy 2020;13:9967-9976
Neuroprotective Role of GLP-1 Analog for Retinal Ganglion Cells via PINK1/Parkin-Mediated Mitophagy in Diabetic Retinopathy.
Zhou HR, Ma XF, Lin WJ, Hao M, Yu XY, Li HX, Xu CY, Kuang HY
Frontiers in pharmacology 2020;11:589114
Frontiers in pharmacology 2020;11:589114
Metformin mitigates gastrointestinal radiotoxicity and radiosensitises P53 mutation colorectal tumours via optimising autophagy.
Chen L, Liao F, Jiang Z, Zhang C, Wang Z, Luo P, Jiang Q, Wu J, Wang Q, Luo M, Li X, Leng Y, Ma L, Shen G, Chen Z, Wang Y, Tan X, Gan Y, Liu D, Liu Y, Shi C
British journal of pharmacology 2020 Sep;177(17):3991-4006
British journal of pharmacology 2020 Sep;177(17):3991-4006
miR-103a-3p regulates mitophagy in Parkinson's disease through Parkin/Ambra1 signaling.
Zhou J, Zhao Y, Li Z, Zhu M, Wang Z, Li Y, Xu T, Feng D, Zhang S, Tang F, Yao J
Pharmacological research 2020 Oct;160:105197
Pharmacological research 2020 Oct;160:105197
Disease-specific phenotypes in iPSC-derived neural stem cells with POLG mutations.
Liang KX, Kristiansen CK, Mostafavi S, Vatne GH, Zantingh GA, Kianian A, Tzoulis C, Høyland LE, Ziegler M, Perez RM, Furriol J, Zhang Z, Balafkan N, Hong Y, Siller R, Sullivan GJ, Bindoff LA
EMBO molecular medicine 2020 Oct 7;12(10):e12146
EMBO molecular medicine 2020 Oct 7;12(10):e12146
Cr (VI) induced mitophagy via the interaction of HMGA2 and PARK2.
Gao Z, Mei J, Yan X, Jiang L, Geng C, Li Q, Shi X, Liu Y, Cao J
Toxicology letters 2020 Oct 15;333:261-268
Toxicology letters 2020 Oct 15;333:261-268
Novel ultrastructural findings on cardiac mitochondria of huddling Brandt's voles in mild cold environment.
Wang Z, Xu JH, Mou JJ, Kong XT, Zou JW, Xue HL, Wu M, Xu LX
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 2020 Nov;249:110766
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 2020 Nov;249:110766
Arsenic induces hepatic insulin resistance via mtROS-NLRP3 inflammasome pathway.
Jia X, Qiu T, Yao X, Jiang L, Wang N, Wei S, Tao Y, Pei P, Wang Z, Zhang J, Zhu Y, Yang G, Liu X, Liu S, Sun X
Journal of hazardous materials 2020 Nov 15;399:123034
Journal of hazardous materials 2020 Nov 15;399:123034
Treadmill Exercise Attenuates Aβ-Induced Mitochondrial Dysfunction and Enhances Mitophagy Activity in APP/PS1 Transgenic Mice.
Zhao N, Yan QW, Xia J, Zhang XL, Li BX, Yin LY, Xu B
Neurochemical research 2020 May;45(5):1202-1214
Neurochemical research 2020 May;45(5):1202-1214
Nestin protects podocyte from injury in lupus nephritis by mitophagy and oxidative stress.
Tian Y, Guo H, Miao X, Xu J, Yang R, Zhao L, Liu J, Yang L, Gao F, Zhang W, Liu Q, Sun S, Tian Y, Li H, Huang J, Gu C, Liu S, Feng X
Cell death & disease 2020 May 5;11(5):319
Cell death & disease 2020 May 5;11(5):319
Silibinin-induced mitochondria fission leads to mitophagy, which attenuates silibinin-induced apoptosis in MCF-7 and MDA-MB-231 cells.
Si L, Fu J, Liu W, Hayashi T, Mizuno K, Hattori S, Fujisaki H, Onodera S, Ikejima T
Archives of biochemistry and biophysics 2020 May 30;685:108284
Archives of biochemistry and biophysics 2020 May 30;685:108284
FSH prevents porcine granulosa cells from hypoxia-induced apoptosis via activating mitophagy through the HIF-1α-PINK1-Parkin pathway.
Li C, Zhou J, Liu Z, Zhou J, Yao W, Tao J, Shen M, Liu H
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Mar;34(3):3631-3645
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Mar;34(3):3631-3645
lncRNA RMST Suppressed GBM Cell Mitophagy through Enhancing FUS SUMOylation.
Liu C, Peng Z, Li P, Fu H, Feng J, Zhang Y, Liu T, Liu Y, Liu Q, Liu Q, Li D, Wu M
Molecular therapy. Nucleic acids 2020 Mar 6;19:1198-1208
Molecular therapy. Nucleic acids 2020 Mar 6;19:1198-1208
ChREBP-β regulates thermogenesis in brown adipose tissue.
Wei C, Ma X, Su K, Qi S, Zhu Y, Lin J, Wang C, Yang R, Chen X, Wang W, Zhang WJ
The Journal of endocrinology 2020 Jun;245(3):343-356
The Journal of endocrinology 2020 Jun;245(3):343-356
DNA damage invokes mitophagy through a pathway involving Spata18.
Dan X, Babbar M, Moore A, Wechter N, Tian J, Mohanty JG, Croteau DL, Bohr VA
Nucleic acids research 2020 Jul 9;48(12):6611-6623
Nucleic acids research 2020 Jul 9;48(12):6611-6623
Qiliqiangxin reduced cardiomyocytes apotosis and improved heart function in infarcted heart through Pink1/Parkin -mediated mitochondrial autophagy.
Zhou J, Wang Z, He Y, Luo X, Zhang W, Yu L, Chen X, He X, Yuan Y, Wang X, Guo X, Tang J, Zhu M, Li D, Ding Y
BMC complementary medicine and therapies 2020 Jul 2;20(1):203
BMC complementary medicine and therapies 2020 Jul 2;20(1):203
Fluoride induced mitochondrial impairment and PINK1-mediated mitophagy in Leydig cells of mice: In vivo and in vitro studies.
Liang C, Gao Y, He Y, Han Y, Manthari RK, Tikka C, Chen C, Wang J, Zhang J
Environmental pollution (Barking, Essex : 1987) 2020 Jan;256:113438
Environmental pollution (Barking, Essex : 1987) 2020 Jan;256:113438
Lactobacillus johnsonii L531 ameliorates enteritis via elimination of damaged mitochondria and suppression of SQSTM1-dependent mitophagy in a Salmonella infantis model of piglet diarrhea.
Xia B, Yu J, He T, Liu X, Su J, Wang M, Wang J, Zhu Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Feb;34(2):2821-2839
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Feb;34(2):2821-2839
NIPA2 regulates osteoblast function by modulating mitophagy in type 2 diabetes osteoporosis.
Zhao W, Zhang W, Ma H, Yang M
Scientific reports 2020 Feb 20;10(1):3078
Scientific reports 2020 Feb 20;10(1):3078
Deregulated MTOR (mechanistic target of rapamycin kinase) is responsible for autophagy defects exacerbating kidney stone development.
Unno R, Kawabata T, Taguchi K, Sugino T, Hamamoto S, Ando R, Okada A, Kohri K, Yoshimori T, Yasui T
Autophagy 2020 Apr;16(4):709-723
Autophagy 2020 Apr;16(4):709-723
Exogenous H(2)S Promoted USP8 Sulfhydration to Regulate Mitophagy in the Hearts of db/db Mice.
Sun Y, Lu F, Yu X, Wang B, Chen J, Lu F, Peng S, Sun X, Yu M, Chen H, Wang Y, Zhang L, Liu N, Du H, Zhao D, Zhang W
Aging and disease 2020 Apr;11(2):269-285
Aging and disease 2020 Apr;11(2):269-285
FOXO3 protects nucleus pulposus cells against apoptosis under nutrient deficiency via autophagy.
Wang Y, Yang Y, Zuo R, Wu J, Zhang C, Li C, Liu M, Zhou Y
Biochemical and biophysical research communications 2020 Apr 9;524(3):756-763
Biochemical and biophysical research communications 2020 Apr 9;524(3):756-763
PINK1/Parkin-Mediated Mitophagy Regulation by Reactive Oxygen Species Alleviates Rocaglamide A-Induced Apoptosis in Pancreatic Cancer Cells.
Zhao C, He R, Shen M, Zhu F, Wang M, Liu Y, Chen H, Li X, Qin R
Frontiers in pharmacology 2019;10:968
Frontiers in pharmacology 2019;10:968
Hepatic DNA Damage Induced by Electronic Cigarette Exposure Is Associated With the Modulation of NAD+/PARP1/SIRT1 Axis.
Espinoza-Derout J, Shao XM, Bankole E, Hasan KM, Mtume N, Liu Y, Sinha-Hikim AP, Friedman TC
Frontiers in endocrinology 2019;10:320
Frontiers in endocrinology 2019;10:320
Bone marrow mesenchymal stem cells repair Cr (VI)- injured kidney by regulating mitochondria-mediated apoptosis and mitophagy mediated via the MAPK signaling pathway.
Yin F, Yan J, Zhao Y, Guo KJ, Zhang ZL, Li AP, Meng CY, Guo L
Ecotoxicology and environmental safety 2019 Jul 30;176:234-241
Ecotoxicology and environmental safety 2019 Jul 30;176:234-241
Liraglutide ameliorates non-alcoholic steatohepatitis by inhibiting NLRP3 inflammasome and pyroptosis activation via mitophagy.
Yu X, Hao M, Liu Y, Ma X, Lin W, Xu Q, Zhou H, Shao N, Kuang H
European journal of pharmacology 2019 Dec 1;864:172715
European journal of pharmacology 2019 Dec 1;864:172715
In mammalian skeletal muscle, phosphorylation of TOMM22 by protein kinase CSNK2/CK2 controls mitophagy.
Kravic B, Harbauer AB, Romanello V, Simeone L, Vögtle FN, Kaiser T, Straubinger M, Huraskin D, Böttcher M, Cerqua C, Martin ED, Poveda-Huertes D, Buttgereit A, Rabalski AJ, Heuss D, Rudolf R, Friedrich O, Litchfield D, Marber M, Salviati L, Mougiakakos D, Neuhuber W, Sandri M, Meisinger C, Hashemolhosseini S
Autophagy 2018;14(2):311-335
Autophagy 2018;14(2):311-335
Mitophagy Directs Muscle-Adipose Crosstalk to Alleviate Dietary Obesity.
Fu T, Xu Z, Liu L, Guo Q, Wu H, Liang X, Zhou D, Xiao L, Liu L, Liu Y, Zhu MS, Chen Q, Gan Z
Cell reports 2018 May 1;23(5):1357-1372
Cell reports 2018 May 1;23(5):1357-1372
PHB2 interacts with LC3 and SQSTM1 is required for bile acids-induced mitophagy in cholestatic liver.
Xiao Y, Zhou Y, Lu Y, Zhou K, Cai W
Cell death & disease 2018 Feb 7;9(2):160
Cell death & disease 2018 Feb 7;9(2):160
Involvement of PINK1/Parkin-mediated mitophagy in paraquat- induced apoptosis in human lung epithelial-like A549 cells.
Sun DZ, Song CQ, Xu YM, Wang R, Liu W, Liu Z, Dong XS
Toxicology in vitro : an international journal published in association with BIBRA 2018 Dec;53:148-159
Toxicology in vitro : an international journal published in association with BIBRA 2018 Dec;53:148-159
Florfenicol-induced Mitochondrial Dysfunction Suppresses Cell Proliferation and Autophagy in Fibroblasts.
Hu D, Cao S, Zhang G, Xiao Y, Liu S, Shang Y
Scientific reports 2017 Oct 19;7(1):13554
Scientific reports 2017 Oct 19;7(1):13554
Polyubiquitination of apurinic/apyrimidinic endonuclease 1 by Parkin.
Scott TL, Wicker CA, Suganya R, Dhar B, Pittman T, Horbinski C, Izumi T
Molecular carcinogenesis 2017 Feb;56(2):325-336
Molecular carcinogenesis 2017 Feb;56(2):325-336
ABT737 induces mitochondrial pathway apoptosis and mitophagy by regulating DRP1-dependent mitochondrial fission in human ovarian cancer cells.
Yu Y, Xu L, Qi L, Wang C, Xu N, Liu S, Li S, Tian H, Liu W, Xu Y, Li Z
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Dec;96:22-29
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Dec;96:22-29
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