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- Antibody Data
- Antigen structure
- References [17]
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- Validations
- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 11288-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11288-1-AP, RRID:AB_2114392
- Product name
- Granzyme A antibody
- Antibody type
- Polyclonal
- Description
- Granzyme A antibody (Cat. #11288-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Structural characterization and antitumor activity via immune modulation of an α-glucan from Grifola frondosa.
Granzyme A-producing type 1 innate lymphoid cells promote salivary secretion in the aged submandibular gland.
Exosite-mediated targeting of GSDMB by dimeric granzyme A in lymphocyte pyroptotic killing.
Metabolic reprogramming in lacrimal gland GVHD: Stage-specific shifts in acinar cells as drivers of disease progression.
Decoding monocyte heterogeneity in sepsis: a single-cell apoptotic signature for immune stratification and guiding precision therapy.
JAK-centric explainable few-shot gene-expression diagnosis framework for alopecia via MultiPLIER priors and relation-style set-to-set comparison.
Single-cell RNA sequencing and cell-cell communication analysis reveal tumor microenvironment associated with chemotherapy responsiveness in ovarian cancer.
Integrated Mendelian Randomization and Single-Cell Transcriptomics Analysis Identifies Critical Blood Biomarkers and Potential Mechanisms in Epilepsy.
Integrated bioinformatics analysis of biomarkers and pathways to explore the mechanisms and molecular targets related to allergic rhinitis and pyroptosis.
PD-L1 targeted peptide demonstrates potent antitumor and immunomodulatory activity in cancer immunotherapy.
GZMA suppressed GPX4-mediated ferroptosis to improve intestinal mucosal barrier function in inflammatory bowel disease.
Single-cell transcriptome profiles the heterogeneity of tumor cells and microenvironments for different pathological endometrial cancer and identifies specific sensitive drugs.
Rapamycin and Low-dose IL-2 Mediate an Immunosuppressive Microenvironment to Inhibit Benign Prostatic Hyperplasia.
Perforin and granzyme A release as novel tool to measure NK cell activation in chickens.
Identification of discrepancy between CTLA4 expression and CTLA4 activation in gastric cancer.
Proteomic profiling of human decidual immune proteins during Toxoplasma gondii infection.
Characterization of cytotoxicity-related gene expression in response to virulent Marek's disease virus infection in the bursa of Fabricius.
Tian HX, Ruan QZ, Xie YZ, Chen W, Xiao C, Zhong W, Liu YC, Chen SD, Yong TQ, Hu HP, Li XM, Wu QP
Carbohydrate polymers 2026 Jun 15;382:125254
Carbohydrate polymers 2026 Jun 15;382:125254
Granzyme A-producing type 1 innate lymphoid cells promote salivary secretion in the aged submandibular gland.
Abe H, Yamashita E, Okuzaki D, Ishii M
Inflammation and regeneration 2026 Jan 29;46(1)
Inflammation and regeneration 2026 Jan 29;46(1)
Exosite-mediated targeting of GSDMB by dimeric granzyme A in lymphocyte pyroptotic killing.
Zhong X, Su Y, Zhou Z, Sun Y, Hou Y, Shao F, Ding J
Immunity 2026 Feb 10;59(2):257-269.e6
Immunity 2026 Feb 10;59(2):257-269.e6
Metabolic reprogramming in lacrimal gland GVHD: Stage-specific shifts in acinar cells as drivers of disease progression.
Jin K, Wang N, Mou C, Yuan K, Wang C, Yuan J, Zheng F, Fang Z, Jin X, He J, Wang Q, Yang S
The ocular surface 2026 Apr;40:89-104
The ocular surface 2026 Apr;40:89-104
Decoding monocyte heterogeneity in sepsis: a single-cell apoptotic signature for immune stratification and guiding precision therapy.
Duan W, Chen Q, Li W, Zhou H, Deng X, Zhang Y
Frontiers in pharmacology 2025;16:1675887
Frontiers in pharmacology 2025;16:1675887
JAK-centric explainable few-shot gene-expression diagnosis framework for alopecia via MultiPLIER priors and relation-style set-to-set comparison.
Yu N, Ran L, Gong X, Teng J, Liu S, Song Z
Frontiers in molecular biosciences 2025;12:1753206
Frontiers in molecular biosciences 2025;12:1753206
Single-cell RNA sequencing and cell-cell communication analysis reveal tumor microenvironment associated with chemotherapy responsiveness in ovarian cancer.
Jiang X, Chen N, Wei Q, Luo X, Liu X, Xie L, Yi P, Xu J
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2025 Mar;27(3):1000-1012
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2025 Mar;27(3):1000-1012
Integrated Mendelian Randomization and Single-Cell Transcriptomics Analysis Identifies Critical Blood Biomarkers and Potential Mechanisms in Epilepsy.
Shi J, Xie J, Yang Y, Fu B, Ye Z, Tang T, Liu Q, Xu J, Wei P, Shan Y, Zhao G
CNS neuroscience & therapeutics 2025 Jan;31(1):e70172
CNS neuroscience & therapeutics 2025 Jan;31(1):e70172
Integrated bioinformatics analysis of biomarkers and pathways to explore the mechanisms and molecular targets related to allergic rhinitis and pyroptosis.
You M, Liu F, Cai Y, Yu G
Scientific reports 2025 Apr 30;15(1):15241
Scientific reports 2025 Apr 30;15(1):15241
PD-L1 targeted peptide demonstrates potent antitumor and immunomodulatory activity in cancer immunotherapy.
Liang Y, Luo H, Li X, Liu S, Habib A, Liu B, Huang J, Wang J, Yi H, Hu B, Zheng L, Xie J, Zhu N
Frontiers in immunology 2024;15:1367040
Frontiers in immunology 2024;15:1367040
GZMA suppressed GPX4-mediated ferroptosis to improve intestinal mucosal barrier function in inflammatory bowel disease.
Niu R, Lan J, Liang D, Xiang L, Wu J, Zhang X, Li Z, Chen H, Geng L, Xu W, Gong S, Yang M
Cell communication and signaling : CCS 2024 Oct 4;22(1):474
Cell communication and signaling : CCS 2024 Oct 4;22(1):474
Single-cell transcriptome profiles the heterogeneity of tumor cells and microenvironments for different pathological endometrial cancer and identifies specific sensitive drugs.
Ren F, Wang L, Wang Y, Wang J, Wang Y, Song X, Zhang G, Nie F, Lin S
Cell death & disease 2024 Aug 7;15(8):571
Cell death & disease 2024 Aug 7;15(8):571
Rapamycin and Low-dose IL-2 Mediate an Immunosuppressive Microenvironment to Inhibit Benign Prostatic Hyperplasia.
Cao T, Xie F, Shi Y, Xu J, Liu Y, Cui D, Zhang F, Lin L, Li W, Gao Y, Ruan Y, Wang X, Zhu Y, Han B, Xia S, Guo W, Li B, Jing Y
International journal of biological sciences 2023;19(11):3441-3455
International journal of biological sciences 2023;19(11):3441-3455
Perforin and granzyme A release as novel tool to measure NK cell activation in chickens.
Ijaz A, Broere F, Rutten VPMG, Jansen CA, Veldhuizen EJA
Developmental and comparative immunology 2023 Dec;149:105047
Developmental and comparative immunology 2023 Dec;149:105047
Identification of discrepancy between CTLA4 expression and CTLA4 activation in gastric cancer.
Xiang Z, Chen W, Zhang J, Song S, Xia GK, Huang XY, Xie J, Yu Y, Zhang QY
Immunopharmacology and immunotoxicology 2019 Jun;41(3):386-393
Immunopharmacology and immunotoxicology 2019 Jun;41(3):386-393
Proteomic profiling of human decidual immune proteins during Toxoplasma gondii infection.
Zhang D, Sun X, Ren L, Yang C, Liu X, Zhang H, Jiang Y, Hu X
Journal of proteomics 2018 Aug 30;186:28-37
Journal of proteomics 2018 Aug 30;186:28-37
Characterization of cytotoxicity-related gene expression in response to virulent Marek's disease virus infection in the bursa of Fabricius.
Chen CY, Xie QM, Xue Y, Ji J, Chang S, Ma JY, Bi YZ
Research in veterinary science 2013 Jun;94(3):496-503
Research in veterinary science 2013 Jun;94(3):496-503
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Jurkat cells were subjected to SDS PAGE followed by western blot with 11288-1-AP(GZMA antibody) at dilution of 1:600
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human lymphoma using 11288-1-AP(GZMA antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Granzyme A antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Granzyme A. This antibody recognizes human, mouse antigen. The Granzyme A antibody has been validated for the following applications: ELISA, WB, IHC analysis.
