orb1088500

antibody from Biorbyt
Targeting: GZMA CTLA3, HFSP
Provider product page for orb1088500
Immunocytochemistry
Immunoprecipitation
Flow cytometry

Antibody data

Product number
orb1088500 - Provider product page
Provider
Biorbyt
Product name
Anti-Hu Granzyme A Purified
Antibody type
Monoclonal
Description
Granzyme A is a serine protease expressed in the cytoplasmic granules of T cells and NK cells. Vectorial secretion of perforin and granzymes is responsible for their granule-mediated cytotoxicity. Similarly to granzyme B, granzyme A acts to destroy the target cells by proteolysis of their particular components. In case of granzyme A the targets are e.g. APEX1 (it destroys its oxidative repair activity), and nucleosome assembly protein SET (it disrupts its nucleosome assembly activity and allows the SET complex to translocate into the nucleus to nick and degrade the DNA).
Reactivity
Human
Conjugate
Unconjugated
Antibody clone number
CB9
Vial size
0.1 mg
Concentration
1 mg/ml
Storage
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
GZMA protein structure - orb1088500 shown in red.