55027-1-AP
antibody from Proteintech Group
Targeting: CSPG4
CSPG4A, HMW-MAA, MCSP, MCSPG, MEL-CSPG, MSK16, NG2
Antibody data
- Antibody Data
- Antigen structure
- References [46]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
Reference
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- Product number
- 55027-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#55027-1-AP, RRID:AB_10791888
- Product name
- CSPG4,NG2 antibody
- Antibody type
- Polyclonal
- Description
- CSPG4,NG2 antibody (Cat. #55027-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Biomimetic core-shell GelMA microspheres co-delivering ANXA1, NGF, and fibronectin enable phase-matched immunomodulation and neurorepair after spinal cord injury.
Oriented porous microtubules combined with CNTF-delivery directional guide axonal regeneration after traumatic optic neuropathy.
Yueju pill exerts long-lasting antidepressant effects through PACAP-mediated NG2 signaling and enhance hippocampal synaptic proteins.
Endothelial Adgrl2 Expression and Alternative Splicing Controls the Cerebrovasculature.
Injectable Brain Extracellular Matrix Hydrogels Enhance Neuronal Migration and Functional Recovery After Intracerebral Hemorrhage.
Single-cell multi-omic and spatial profiling of esophageal squamous cell carcinoma reveals the immunosuppressive role of GPR116(+) pericytes in cancer metastasis.
P-Pev: micelle-like complexes transformed from tumor extracellular vesicles by PEG-PE for personalized therapeutic tumor vaccine.
Interplay of axon regeneration genes and immune infiltration in spinal cord injury.
PRRX1 Orchestrates Pericyte-Myofibroblast Transition in Pathological Retinal Fibrosis.
SPP1-mediated crosstalk between macrophage and fibroblasts promotes benign airway stenosis.
CD44 is a macrophage receptor for TcdB from Clostridioides difficile that via its lysine-158 succinylation contributes to inflammation.
Maternal-infant probiotic transmission mitigates early-life stress-induced autism in mice.
Chondroitin sulfate proteoglycan 4 (CSPG4) overexpression as an oncogenic driver and prognostic marker for unfavorable outcomes in hepatocellular carcinoma.
Electroacupuncture Protects Against Post-stroke Cognitive Impairment by Promoting an IL-33/ST2 Axis-Mediated Microglia M2 Polarization.
FGF21 Alleviates Hypoxic-Ischemic White Matter Injury in Neonatal Mice by Mediating Inflammation and Oxidative Stress Through PPAR-γ Signaling Pathway.
Lysyl hydroxylase 2 glucosylates collagen VI to drive lung cancer progression.
The Neuroprotective Mechanisms of PPAR-γ: Inhibition of Microglia-Mediated Neuroinflammation and Oxidative Stress in a Neonatal Mouse Model of Hypoxic-Ischemic White Matter Injury.
CDDO regulates central and peripheral sensitization to attenuate post-herpetic neuralgia by targeting TRPV1/PKC-δ/p-Akt signals.
Integrin β8 prevents pericyte-myofibroblast transition and renal fibrosis through inhibiting the TGF-β1/TGFBR1/Smad3 pathway in diabetic kidney disease.
Acid Neutralization by Composite Lysine Nanoparticles for Spinal Cord Injury Recovery through Mitigating Mitochondrial Dysfunction.
Pericytes recruited by CCL28 promote vascular normalization after anti-angiogenesis therapy through RA/RXRA/ANGPT1 pathway in lung adenocarcinoma.
Tumor microenvironment reprogramming combined with immunogenic enhancement by nanoemulsions potentiates immunotherapy.
The mechanism of chemokine receptor ACKR2 in cognitive impairment in young rats with traumatic brain injury.
A method to isolate human dermal microvascular pericytes without the use of magnetic beads sorting in vitro.
FNIP1 abrogation promotes functional revascularization of ischemic skeletal muscle by driving macrophage recruitment.
USP1/UAF1-Stabilized METTL3 Promotes Reactive Astrogliosis and Improves Functional Recovery after Spinal Cord Injury through m(6)A Modification of YAP1 mRNA.
Complete remission of diabetes with a transient HDAC inhibitor and insulin in streptozotocin mice.
Bone Marrow-Derived Mesenchymal Stem Cells Transplantation Attenuates Renal Fibrosis Following Acute Kidney Injury in Rats by Diminishing Pericyte-Myofibroblast Transition and Extracellular Matrix Augment.
Establishment and validation of a plasma oncofetal chondroitin sulfated proteoglycan for pan-cancer detection.
Neuron-Derived Exosomes Promote the Recovery of Spinal Cord Injury by Modulating Nerve Cells in the Cellular Microenvironment of the Lesion Area.
Chondroitin Sulphate Proteoglycan Axonal Coats in the Human Mediodorsal Thalamic Nucleus.
Pericyte mediates the infiltration, migration, and polarization of macrophages by CD163/MCAM axis in glioblastoma.
Guidance landscapes unveiled by quantitative proteomics to control reinnervation in adult visual system.
Bone marrow-derived vasculogenesis leads to scarless regeneration in deep wounds with periosteal defects.
Geniposide alleviates VEGF-induced angiogenesis by inhibiting VEGFR2/PKC/ERK1/2-mediated SphK1 translocation.
Matrine inhibits the Wnt3a/β-catenin/TCF7L2 signaling pathway in experimental autoimmune encephalomyelitis.
Expanding tubular microvessels on stiff substrates with endothelial cells and pericytes from the same adult tissue.
Fascin-1 is Highly Expressed Specifically in Microglia After Spinal Cord Injury and Regulates Microglial Migration.
Melatonin pretreatment alleviates the long-term synaptic toxicity and dysmyelination induced by neonatal Sevoflurane exposure via MT1 receptor-mediated Wnt signaling modulation.
Amelioration of clinical course and demyelination in the cuprizone mouse model in relation to ketogenic diet.
NLRP3 inflammasome-mediated microglial pyroptosis is critically involved in the development of post-cardiac arrest brain injury.
Targeting aurora kinase B alleviates spinal microgliosis and neuropathic pain in a rat model of peripheral nerve injury.
Matrine alleviates astrogliosis through sphingosine 1-phosphate signaling in experimental autoimmune encephalomyelitis.
Association between Alzheimer's disease pathogenesis and early demyelination and oligodendrocyte dysfunction.
ST8SIA2 promotes oligodendrocyte differentiation and the integrity of myelin and axons.
A global analysis of SNX27-retromer assembly and cargo specificity reveals a function in glucose and metal ion transport.
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Endothelial Adgrl2 Expression and Alternative Splicing Controls the Cerebrovasculature.
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Integrin β8 prevents pericyte-myofibroblast transition and renal fibrosis through inhibiting the TGF-β1/TGFBR1/Smad3 pathway in diabetic kidney disease.
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A method to isolate human dermal microvascular pericytes without the use of magnetic beads sorting in vitro.
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FNIP1 abrogation promotes functional revascularization of ischemic skeletal muscle by driving macrophage recruitment.
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Establishment and validation of a plasma oncofetal chondroitin sulfated proteoglycan for pan-cancer detection.
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Neuron-Derived Exosomes Promote the Recovery of Spinal Cord Injury by Modulating Nerve Cells in the Cellular Microenvironment of the Lesion Area.
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Molecular neurobiology 2023 Aug;60(8):4502-4516
Chondroitin Sulphate Proteoglycan Axonal Coats in the Human Mediodorsal Thalamic Nucleus.
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Frontiers in integrative neuroscience 2022;16:934764
Pericyte mediates the infiltration, migration, and polarization of macrophages by CD163/MCAM axis in glioblastoma.
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iScience 2022 Sep 16;25(9):104918
iScience 2022 Sep 16;25(9):104918
Guidance landscapes unveiled by quantitative proteomics to control reinnervation in adult visual system.
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Nature communications 2022 Oct 13;13(1):6040
Bone marrow-derived vasculogenesis leads to scarless regeneration in deep wounds with periosteal defects.
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Scientific reports 2022 Nov 29;12(1):20589
Geniposide alleviates VEGF-induced angiogenesis by inhibiting VEGFR2/PKC/ERK1/2-mediated SphK1 translocation.
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Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jun;100:154068
Matrine inhibits the Wnt3a/β-catenin/TCF7L2 signaling pathway in experimental autoimmune encephalomyelitis.
Ma R, Chu Y, Dou M, Jing Y, Zhao X, Li X, Li S, Zhang Y, Wang L, Zhu L
Journal of neuroimmunology 2022 Jun 15;367:577876
Journal of neuroimmunology 2022 Jun 15;367:577876
Expanding tubular microvessels on stiff substrates with endothelial cells and pericytes from the same adult tissue.
Song X, Yu Y, Leng Y, Ma L, Mu J, Wang Z, Xu Y, Zhu H, Qiu X, Li P, Li J, Wang D
Journal of tissue engineering 2022 Jan-Dec;13:20417314221125310
Journal of tissue engineering 2022 Jan-Dec;13:20417314221125310
Fascin-1 is Highly Expressed Specifically in Microglia After Spinal Cord Injury and Regulates Microglial Migration.
Yu S, Cheng L, Tian D, Li Z, Yao F, Luo Y, Liu Y, Zhu Z, Zheng M, Jing J
Frontiers in pharmacology 2021;12:729524
Frontiers in pharmacology 2021;12:729524
Melatonin pretreatment alleviates the long-term synaptic toxicity and dysmyelination induced by neonatal Sevoflurane exposure via MT1 receptor-mediated Wnt signaling modulation.
Liang L, Zeng T, Zhao Y, Lu R, Guo B, Xie R, Tang W, Zhang L, Mao Z, Yang X, Wu S, Wang Y, Zhang H
Journal of pineal research 2021 Dec;71(4):e12771
Journal of pineal research 2021 Dec;71(4):e12771
Amelioration of clinical course and demyelination in the cuprizone mouse model in relation to ketogenic diet.
Zhang N, Liu C, Zhang R, Jin L, Yin X, Zheng X, Siebert HC, Li Y, Wang Z, Loers G, Petridis AK
Food & function 2020 Jun 24;11(6):5647-5663
Food & function 2020 Jun 24;11(6):5647-5663
NLRP3 inflammasome-mediated microglial pyroptosis is critically involved in the development of post-cardiac arrest brain injury.
Chang Y, Zhu J, Wang D, Li H, He Y, Liu K, Wang X, Peng Y, Pan S, Huang K
Journal of neuroinflammation 2020 Jul 23;17(1):219
Journal of neuroinflammation 2020 Jul 23;17(1):219
Targeting aurora kinase B alleviates spinal microgliosis and neuropathic pain in a rat model of peripheral nerve injury.
Shen Y, Ding Z, Ma S, Zou Y, Yang X, Ding Z, Zhang Y, Zhu X, Schäfer MKE, Guo Q, Huang C
Journal of neurochemistry 2020 Jan;152(1):72-91
Journal of neurochemistry 2020 Jan;152(1):72-91
Matrine alleviates astrogliosis through sphingosine 1-phosphate signaling in experimental autoimmune encephalomyelitis.
Ma W, Zhang M, Liu S, Wang M, Shi Y, Yang T, Li X, Zhu L
Neuroscience letters 2020 Jan 10;715:134599
Neuroscience letters 2020 Jan 10;715:134599
Association between Alzheimer's disease pathogenesis and early demyelination and oligodendrocyte dysfunction.
Dong YX, Zhang HY, Li HY, Liu PH, Sui Y, Sun XH
Neural regeneration research 2018 May;13(5):908-914
Neural regeneration research 2018 May;13(5):908-914
ST8SIA2 promotes oligodendrocyte differentiation and the integrity of myelin and axons.
Szewczyk LM, Brozko N, Nagalski A, Röckle I, Werneburg S, Hildebrandt H, Wisniewska MB, Kuznicki J
Glia 2017 Jan;65(1):34-49
Glia 2017 Jan;65(1):34-49
A global analysis of SNX27-retromer assembly and cargo specificity reveals a function in glucose and metal ion transport.
Steinberg F, Gallon M, Winfield M, Thomas EC, Bell AJ, Heesom KJ, Tavaré JM, Cullen PJ
Nature cell biology 2013 May;15(5):461-71
Nature cell biology 2013 May;15(5):461-71
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- A375 cells were subjected to SDS PAGE followed by western blot with 55027-1-AP(CSPG4,NG2 antibody) at dilution of 1:300
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The CSPG4,NG2 antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human CSPG4,NG2. This antibody recognizes human,mouse,rat antigen. The CSPG4,NG2 antibody has been validated for the following applications: ELISA, WB, IHC analysis.