BS7912

antibody from Bioworld Technology, Inc
Targeting: ABT1 Esf2
Provider product page for BS7912
Western blot
Immunohistochemistry

Antibody data

Product number
BS7912 - Provider product page
Provider
Bioworld Technology, Inc
Product name
ABT1 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human ABT1.
Description
ABT1 (activator of basal transcription 1) is a nuclear protein that associates with the TATA-binding protein (TBP) and enhances basal transcription activity of class II promoters. ABT1 associates with TBP in HeLa nuclear extracts in vitro. Another protein, designated ERF, is a member of the ETS family of transcription factors. The members of the ETS family are grouped because they share a highly conserved DNA binding domain. These factors are involved in growth factor pathways and regulate both proliferation and differentiation. ERF (Ets2 Repressor Factor) is a ubiquitously expressed ets-domain protein that exhibits strong transcriptional repressor activity, suppresses ets-induced transformation and is regulated by MAPK phosphorylation. ERF transcription may be regulated by ets-domain proteins. Additionally, modulation of ERF activity is involved in the transcriptional regulation of genes activated during entry into G 1 phase.
Reactivity
Human, Mouse
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
ABT1 protein structure - BS7912 shown in red.