13364-1-AP

antibody from Proteintech Group

Targeting: LMAN1 ERGIC-53, ERGIC53, F5F8D, FMFD1, gp58, MCFD1, MR60

Provider product page for 13364-1-AP

Western blot

ELISA

Immunocytochemistry

Immunoprecipitation

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [31]
Comments [0]
Validations
Western blot [1]
Immunohistochemistry [2]

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Product number: 13364-1-AP - Provider product page
Provider: Proteintech Group
Proper citation: Proteintech Cat#13364-1-AP, RRID:AB_2135994
Product name: ERGIC-53 antibody
Antibody type: Polyclonal
Description: KD/KO validated ERGIC-53 antibody (Cat. #13364-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

LMAN1 protein structure - 13364-1-AP shown in red.

Submitted references A dual role for ER-Golgi cargo receptor LMAN1 in supporting CSFV replication and restraining RLR signaling.

Han K, Chang Z, Li N, Xiao D, Song M, Wang T, Guo K, Zhang L, Deng W
Journal of virology 2026 Mar 24;100(3):e0006926

STING COPII ER Export Trafficking and Signaling Primed by Phosphorylation Switches.

Nan Y, Cui D, Guo J, Ma X, Wang J, Guo L, Li T, Yang M, Huang G, Xu A, Ma W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(36):e03660

Distinct pathogenic mutations in ARF1 allow dissection of its dual role in cGAS-STING signalling.

Lang J, Bergner T, Zinngrebe J, Lepelley A, Vill K, Leiz S, Wlaschek M, Wagner M, Scharffetter-Kochanek K, Fischer-Posovszky P, Read C, Crow YJ, Hirschenberger M, Sparrer KMJ
EMBO reports 2025 May;26(9):2232-2261

Coatomer complex I is required for the transport of SARS-CoV-2 progeny virions from the endoplasmic reticulum-Golgi intermediate compartment.

Hirabayashi A, Muramoto Y, Takenaga T, Tsunoda Y, Wakazaki M, Sato M, Fujita-Fujiharu Y, Nomura N, Yamauchi K, Onishi C, Nakano M, Toyooka K, Noda T
mBio 2025 Jan 8;16(1):e0333124

Coronavirus membrane protein with a fluorescent protein tag enables tracking of virus particles in live cells.

Stefanos B, Green NRB, Nadig I, Lapierre LA, Goldenring JR, Hogue IB, Glenn HL, Hogue BG
bioRxiv : the preprint server for biology 2025 Dec 30;

AP-1 contributes to endosomal targeting of the ubiquitin ligase RNF13 via a secondary and novel non-canonical binding motif.

Cabana VC, Sénécal AM, Bouchard AY, Kourrich S, Cappadocia L, Lussier MP
Journal of cell science 2024 Sep 15;137(18)

SARS-CoV-2 remodels the Golgi apparatus to facilitate viral assembly and secretion.

Zhang J, Kennedy A, de Melo Jorge DM, Xing L, Reid W, Bui S, Joppich J, Rose M, Ercan S, Tang Q, Tai AW, Wang Y
bioRxiv : the preprint server for biology 2024 Mar 15;

The p24-family and COPII subunit SEC24C facilitate the clearance of alpha1-antitrypsin Z from the endoplasmic reticulum to lysosomes.

Roberts BS, Mitra D, Abishek S, Beher R, Satpute-Krishnan P
Molecular biology of the cell 2024 Mar 1;35(3):ar45

A substitution at the cytoplasmic tail of the spike protein enhances SARS-CoV-2 infectivity and immunogenicity.

Li Y, Zhang X, Tai W, Zhuang X, Shi H, Liao S, Yu X, Mei R, Chen X, Huang Y, Liu Y, Liu J, Liu Y, Zhu Y, Wang P, Tian M, Yu G, Li L, Cheng G
EBioMedicine 2024 Dec;110:105437

Tracing genetic diversity captures the molecular basis of misfolding disease.

Zhao P, Wang C, Sun S, Wang X, Balch WE
Nature communications 2024 Apr 18;15(1):3333

Common Markers and Small Molecule Inhibitors in Golgi Studies.

Bui S, Stark D, Li J, Zhang J, Wang Y
Methods in molecular biology (Clifton, N.J.) 2023;2557:453-493

Immunofluorescence Microscopy of the Mammalian Golgi Apparatus.

Arab M, Nayak SC, Vitali T, Lowe M
Methods in molecular biology (Clifton, N.J.) 2023;2557:101-111

Manganese regulation of COPII condensation controls circulating lipid homeostasis.

Wang X, Huang R, Wang Y, Zhou W, Hu Y, Yao Y, Cheng K, Li X, Xu B, Zhang J, Xu Y, Zeng F, Zhu Y, Chen XW
Nature cell biology 2023 Nov;25(11):1650-1663

ARF1 prevents aberrant type I interferon induction by regulating STING activation and recycling.

Hirschenberger M, Lepelley A, Rupp U, Klute S, Hunszinger V, Koepke L, Merold V, Didry-Barca B, Wondany F, Bergner T, Moreau T, Rodero MP, Rösler R, Wiese S, Volpi S, Gattorno M, Papa R, Lynch SA, Haug MG, Houge G, Wigby KM, Sprague J, Lenberg J, Read C, Walther P, Michaelis J, Kirchhoff F, de Oliveira Mann CC, Crow YJ, Sparrer KMJ
Nature communications 2023 Nov 1;14(1):6770

Development of VHL-recruiting STING PROTACs that suppress innate immunity.

Zhu Z, Johnson RL, Zhang Z, Herring LE, Jiang G, Damania B, James LI, Liu P
Cellular and molecular life sciences : CMLS 2023 May 14;80(6):149

The Envelope Proteins from SARS-CoV-2 and SARS-CoV Potently Reduce the Infectivity of Human Immunodeficiency Virus type 1 (HIV-1).

Henke W, Waisner H, Arachchige SP, Kalamvoki M, Stephens E
Research square 2022 Oct 24;

The envelope proteins from SARS-CoV-2 and SARS-CoV potently reduce the infectivity of human immunodeficiency virus type 1 (HIV-1).

Henke W, Waisner H, Arachchige SP, Kalamvoki M, Stephens E
Retrovirology 2022 Nov 19;19(1):25

Bunyavirus SFTSV exploits autophagic flux for viral assembly and egress.

Yan JM, Zhang WK, Yan LN, Jiao YJ, Zhou CM, Yu XJ
Autophagy 2022 Jul;18(7):1599-1612

Collagen has a unique SEC24 preference for efficient export from the endoplasmic reticulum.

Lu CL, Ortmeier S, Brudvig J, Moretti T, Cain J, Boyadjiev SA, Weimer JM, Kim J
Traffic (Copenhagen, Denmark) 2022 Jan;23(1):81-93

STING1 is essential for an RNA-virus triggered autophagy.

Zhang R, Qin X, Yang Y, Zhu X, Zhao S, Zhang Z, Su Q, Zhao Z, Yin X, Meng X, Zhang Z, Li Y
Autophagy 2022 Apr;18(4):816-828

Subcellular localization of nucleocapsid protein of SFTSV and its assembly into the ribonucleoprotein complex with L protein and viral RNA.

Lokupathirage SMW, Tsuda Y, Ikegame K, Noda K, Muthusinghe DS, Kozawa F, Manzoor R, Shimizu K, Yoshimatsu K
Scientific reports 2021 Nov 26;11(1):22977

Homeostatic regulation of STING by retrograde membrane traffic to the ER.

Mukai K, Ogawa E, Uematsu R, Kuchitsu Y, Kiku F, Uemura T, Waguri S, Suzuki T, Dohmae N, Arai H, Shum AK, Taguchi T
Nature communications 2021 Jan 4;12(1):61

Receptor-Mediated ER Export of Lipoproteins Controls Lipid Homeostasis in Mice and Humans.

Wang X, Wang H, Xu B, Huang D, Nie C, Pu L, Zajac GJM, Yan H, Zhao J, Shi F, Emmer BT, Lu J, Wang R, Dong X, Dai J, Zhou W, Wang C, Gao G, Wang Y, Willer C, Lu X, Zhu Y, Chen XW
Cell metabolism 2021 Feb 2;33(2):350-366.e7

BET1 variants establish impaired vesicular transport as a cause for muscular dystrophy with epilepsy.

Donkervoort S, Krause N, Dergai M, Yun P, Koliwer J, Gorokhova S, Geist Hauserman J, Cummings BB, Hu Y, Smith R, Uapinyoying P, Ganesh VS, Ghosh PS, Monaghan KG, Edassery SL, Ferle PE, Silverstein S, Chao KR, Snyder M, Ellingwood S, Bharucha-Goebel D, Iannaccone ST, Dal Peraro M, Foley AR, Savas JN, Bolduc V, Fasshauer D, Bönnemann CG, Schwake M
EMBO molecular medicine 2021 Dec 7;13(12):e13787

TMEM41B acts as an ER scramblase required for lipoprotein biogenesis and lipid homeostasis.

Huang D, Xu B, Liu L, Wu L, Zhu Y, Ghanbarpour A, Wang Y, Chen FJ, Lyu J, Hu Y, Kang Y, Zhou W, Wang X, Ding W, Li X, Jiang Z, Chen J, Zhang X, Zhou H, Li JZ, Guo C, Zheng W, Zhang X, Li P, Melia T, Reinisch K, Chen XW
Cell metabolism 2021 Aug 3;33(8):1655-1670.e8

Improved secretion of glycoproteins using an N-glycan-restricted passport sequence tag recognized by cargo receptor.

Yagi H, Yagi-Utsumi M, Honda R, Ohta Y, Saito T, Nishio M, Ninagawa S, Suzuki K, Anzai T, Kamiya Y, Aoki K, Nakanishi M, Satoh T, Kato K
Nature communications 2020 Mar 13;11(1):1368

Blood coagulation factor VIII D1241E polymorphism leads to a weak malectin interaction and reduction of factor VIII posttranslational modification and secretion.

Jiang N, Xiao Y, Liu Y, Liu W, Liu S
Experimental cell research 2020 Dec 1;397(1):112334

Multiple coagulation factor deficiency protein 2 as a crucial component in metastasis of human oral cancer.

Fukamachi M, Kasamatsu A, Endo-Sakamoto Y, Fushimi K, Kasama H, Iyoda M, Minakawa Y, Shiiba M, Tanzawa H, Uzawa K
Experimental cell research 2018 Jul 1;368(1):119-125

An atlas of bloodstream-accessible bone marrow proteins for site-directed therapy of acute myeloid leukemia.

Angenendt L, Reuter S, Kentrup D, Benk AS, Neumann F, Hüve J, Martens AC, Schwöppe C, Kessler T, Schmidt LH, Sauer T, Brand C, Mikesch JH, Lenz G, Mesters RM, Müller-Tidow C, Hartmann W, Wardelmann E, Neri D, Berdel WE, Roesli C, Schliemann C
Leukemia 2018 Feb;32(2):510-519

Hepatic loss of Lissencephaly 1 (Lis1) induces fatty liver and accelerates liver tumorigenesis in mice.

Li X, Liu L, Li R, Wu A, Lu J, Wu Q, Jia J, Zhao M, Song H
The Journal of biological chemistry 2018 Apr 6;293(14):5160-5171

Ehrlichia chaffeensis Tandem Repeat Effector Targets Differentially Influence Infection.

Luo T, Dunphy PS, McBride JW
Frontiers in cellular and infection microbiology 2017;7:178

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: human brain tissue were subjected to SDS PAGE followed by western blot with 13364-1-AP(LMAN1 antibody) at dilution of 1:400
Sample type: tissue

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: Immunohistochemical of paraffin-embedded human stomach cancer using 13364-1-AP(LMAN1 antibody) at dilution of 1:100 (under 10x lens)
Sample type: tissue

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: The LMAN1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human LMAN1. This antibody recognizes human, mouse, rat antigen. The LMAN1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
Appendix: 13364-1-AP.pdf

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