41-3239-82

antibody from Invitrogen Antibodies
Targeting: JAM3 JAM-C, JAMC
Provider product page for 41-3239-82
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
41-3239-82 - Provider product page
Provider
Invitrogen Antibodies
Product name
Anti-CD323 (JAM3) Monoclonal Antibody (SHM33), eFluor 570, eBioscience™
Antibody type
Monoclonal
Antigen
Other
Description
Description: The SHM33 monoclonal antibody reacts with human CD323, which is also known as Junctional Adhesion Molecule (JAM) 3. A member of the Ig superfamily of transmembrane proteins, CD323 is expressed on endothelial and epithelial cells, smooth muscle cells, peripheral nerves, platelets, and some B cells. In addition, this receptor is expressed on VEGF and histamine-stimulated endothelial cells, as well as on activated T cells. CD323 is involved in neutrophil transmigration during inflammation, angiogenesis, cell polarity, and nerve conduction. CD323 interacts homo- and heterotypically with beta2 and beta3 integrins, JAM2, and the viral receptor CAR. Applications Reported: This SHM33 antibody has been reported for use in microscopy, immunohistochemical staining, and immunocytochemistry. Applications Tested: This SHM33 antibody has been tested by immunocytochemistry of methanol-fixed human cells and can be used at less than or equal to 1 µg/mL. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Filter Recommendation: When using this eFluor® 570 antibody conjugate, we recommend a filter that will capture the 570 emission wavelength (for example, Excitation 545/25, 565LP, Emission 605/70). A standard Alexa Fluor® 555 or TRITC filter is acceptable. Excitation: 555 nm; Emission: 570 nm
Reactivity
Human
Host
Mouse
Isotype
IgG
Antibody clone number
SHM33
Vial size
100 µg
Concentration
0.2 mg/mL
Storage
4° C, store in dark, DO NOT FREEZE!
JAM3 protein structure - 41-3239-82 shown in red.