Antibody data
- Antibody Data
- Antigen structure
- References [13]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 11331-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11331-1-AP, RRID:AB_2098155
- Product name
- XPG antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated XPG antibody (Cat. #11331-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IP, WB, ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references RNA helicase DDX3 regulates RAD51 localization and DNA damage repair in Ewing sarcoma.
NAT10 regulates the repair of UVB-induced DNA damage and tumorigenicity.
XPF interacts with TOP2B for R-loop processing and DNA looping on actively transcribed genes.
RNA Helicase DDX3 Regulates RAD51 Localization and DNA Damage Repair in Ewing Sarcoma.
NKAP acts with HDAC3 to prevent R-loop associated genome instability.
DNMT3b protects centromere integrity by restricting R-loop-mediated DNA damage.
Sustained Aurora Kinase B Expression Confers Resistance to PI3K Inhibition in Head and Neck Squamous Cell Carcinoma.
Characterization of the nucleotide excision repair pathway and evaluation of compounds for overcoming the cisplatin resistance of non‑small cell lung cancer cell lines.
CLEC4M is associated with poor prognosis and promotes cisplatin resistance in NSCLC patients.
Human Rad52 Promotes XPG-Mediated R-loop Processing to Initiate Transcription-Associated Homologous Recombination Repair.
Systematic Functional Annotation of Somatic Mutations in Cancer.
Associations between expression levels of nucleotide excision repair proteins in lymphoblastoid cells and risk of squamous cell carcinoma of the head and neck.
Stimulation of ribosomal RNA gene promoter by transcription factor Sp1 involves active DNA demethylation by Gadd45-NER pathway.
Randolph ME, Afifi M, Gorthi A, Weil R, Wilky BA, Weinreb J, Ciero P, Hoeve NT, van Diest PJ, Raman V, Bishop AJR, Loeb DM
iScience 2024 Feb 16;27(2):108925
iScience 2024 Feb 16;27(2):108925
NAT10 regulates the repair of UVB-induced DNA damage and tumorigenicity.
Yang Z, Wilkinson E, Cui YH, Li H, He YY
Toxicology and applied pharmacology 2023 Oct 15;477:116688
Toxicology and applied pharmacology 2023 Oct 15;477:116688
XPF interacts with TOP2B for R-loop processing and DNA looping on actively transcribed genes.
Chatzinikolaou G, Stratigi K, Siametis A, Goulielmaki E, Akalestou-Clocher A, Tsamardinos I, Topalis P, Austin C, Bouwman BAM, Crosetto N, Altmüller J, Garinis GA
Science advances 2023 Nov 10;9(45):eadi2095
Science advances 2023 Nov 10;9(45):eadi2095
RNA Helicase DDX3 Regulates RAD51 Localization and DNA Damage Repair in Ewing Sarcoma.
Randolph ME, Afifi M, Gorthi A, Weil R, Wilky BA, Weinreb J, Ciero P, Ter Hoeve N, van Diest PJ, Raman V, Bishop AJR, Loeb DM
bioRxiv : the preprint server for biology 2023 Jun 10;
bioRxiv : the preprint server for biology 2023 Jun 10;
NKAP acts with HDAC3 to prevent R-loop associated genome instability.
Zhang X, Duan J, Li Y, Jin X, Wu C, Yang X, Lu W, Ge W
Cell death and differentiation 2023 Jul;30(7):1811-1828
Cell death and differentiation 2023 Jul;30(7):1811-1828
DNMT3b protects centromere integrity by restricting R-loop-mediated DNA damage.
Shih HT, Chen WY, Wang HY, Chao T, Huang HD, Chou CH, Chang ZF
Cell death & disease 2022 Jun 11;13(6):546
Cell death & disease 2022 Jun 11;13(6):546
Sustained Aurora Kinase B Expression Confers Resistance to PI3K Inhibition in Head and Neck Squamous Cell Carcinoma.
Shah PA, Sambandam V, Fernandez AM, Zhao H, Mazumdar T, Shen L, Wang Q, Ahmed KM, Ghosh S, Frederick MJ, Wang J, Johnson FM
Cancer research 2022 Dec 2;82(23):4444-4456
Cancer research 2022 Dec 2;82(23):4444-4456
Characterization of the nucleotide excision repair pathway and evaluation of compounds for overcoming the cisplatin resistance of non‑small cell lung cancer cell lines.
Suzuki T, Sirimangkalakitti N, Baba A, Toyoshima-Nagasaki R, Enomoto Y, Saito N, Ogasawara Y
Oncology reports 2022 Apr;47(4)
Oncology reports 2022 Apr;47(4)
CLEC4M is associated with poor prognosis and promotes cisplatin resistance in NSCLC patients.
Tan LM, Li X, Qiu CF, Zhu T, Hu CP, Yin JY, Zhang W, Zhou HH, Liu ZQ
Journal of Cancer 2019;10(25):6374-6383
Journal of Cancer 2019;10(25):6374-6383
Human Rad52 Promotes XPG-Mediated R-loop Processing to Initiate Transcription-Associated Homologous Recombination Repair.
Yasuhara T, Kato R, Hagiwara Y, Shiotani B, Yamauchi M, Nakada S, Shibata A, Miyagawa K
Cell 2018 Oct 4;175(2):558-570.e11
Cell 2018 Oct 4;175(2):558-570.e11
Systematic Functional Annotation of Somatic Mutations in Cancer.
Ng PK, Li J, Jeong KJ, Shao S, Chen H, Tsang YH, Sengupta S, Wang Z, Bhavana VH, Tran R, Soewito S, Minussi DC, Moreno D, Kong K, Dogruluk T, Lu H, Gao J, Tokheim C, Zhou DC, Johnson AM, Zeng J, Ip CKM, Ju Z, Wester M, Yu S, Li Y, Vellano CP, Schultz N, Karchin R, Ding L, Lu Y, Cheung LWT, Chen K, Shaw KR, Meric-Bernstam F, Scott KL, Yi S, Sahni N, Liang H, Mills GB
Cancer cell 2018 Mar 12;33(3):450-462.e10
Cancer cell 2018 Mar 12;33(3):450-462.e10
Associations between expression levels of nucleotide excision repair proteins in lymphoblastoid cells and risk of squamous cell carcinoma of the head and neck.
Han P, Liu H, Shi Q, Liu Z, Troy JD, Lee WT, Zevallos JP, Li G, Sturgis EM, Wei Q
Molecular carcinogenesis 2018 Jun;57(6):784-793
Molecular carcinogenesis 2018 Jun;57(6):784-793
Stimulation of ribosomal RNA gene promoter by transcription factor Sp1 involves active DNA demethylation by Gadd45-NER pathway.
Rajput P, Pandey V, Kumar V
Biochimica et biophysica acta 2016 Aug;1859(8):953-63
Biochimica et biophysica acta 2016 Aug;1859(8):953-63
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The XPG antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human XPG. This antibody recognizes human antigen. The XPG antibody has been validated for the following applications: ELISA, WB analysis.