13-9817-82

antibody from Invitrogen Antibodies
Targeting: RUNX3 AML2, CBFA3, PEBP2A3
Provider product page for 13-9817-82
Western blot
Immunohistochemistry

Antibody data

Product number
13-9817-82 - Provider product page
Provider
Invitrogen Antibodies
Product name
Anti-RUNX3 Monoclonal Antibody (R3-5G4), Biotin, eBioscience™
Antibody type
Monoclonal
Antigen
Other
Description
Description: This R3-5G4 monoclonal antibody recognizes human Runx3, a 44 kDa transcription factor that belongs to the Runt domain-containing family. Runx3 is expressed in hematopoietic cells such as T cells, B cells, and myeloid cells. This transcription factor is also expressed in non-hematopoietic tissues, including the epidermis, bone, and dorsal root ganglia. Runx3 has been established to play a critical role in thymocyte development. More specifically, Runx3 promotes CD8 + T cell development by silencing Cd4 expression. Finally, studies have demonstrated the tumor suppressive activity of in a variety of cancers (e.g., gastric and breast cancers). Applications Reported: This R3-5G4 antibody has been reported for use in western blotting, and immunohistochemical staining of formalin-fixed paraffin embedded tissue sections. Applications Tested: This R3-5G4 antibody has been tested by immunohistochemistry on human FFPE tissue sections using high pH antigen retrieval at less than or equal to 20 µg/mL. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Filtration: 0.2 µm post-manufacturing filtered.
Reactivity
Human
Host
Mouse
Conjugate
Biotin
Isotype
IgG
Antibody clone number
R3-5G4
Vial size
100 µg
Concentration
0.5 mg/mL
Storage
4° C, store in dark, DO NOT FREEZE!
RUNX3 protein structure - 13-9817-82 shown in red.