Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Immunocytochemistry [2]
Submit
Validation data
Reference
Comment
Report error
- Product number
- ALX-803-318-C100 - Provider product page
- Provider
- Enzo Life Sciences
- Proper citation
- Enzo Life Sciences Cat#ALX-803-318-C100, RRID:AB_2052515
- Product name
- RUNX3 (human) monoclonal antibody (R3-6E9)
- Antibody type
- Monoclonal
- Antigen
- Recombinant protein fragment
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- R3-6E9
- Vial size
- 100 μg
- Storage
- -20°C
- Handling
- Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20¡C.
Submitted references Targets of genome copy number reduction in primary breast cancers identified by integrative genomics.
RUNX3 is frequently inactivated by dual mechanisms of protein mislocalization and promoter hypermethylation in breast cancer.
RUNX3, a novel tumor suppressor, is frequently inactivated in gastric cancer by protein mislocalization.
Chen W, Salto-Tellez M, Palanisamy N, Ganesan K, Hou Q, Tan LK, Sii LH, Ito K, Tan B, Wu J, Tay A, Tan KC, Ang E, Tan BK, Tan PH, Ito Y, Tan P
Genes, chromosomes & cancer 2007 Mar;46(3):288-301
Genes, chromosomes & cancer 2007 Mar;46(3):288-301
RUNX3 is frequently inactivated by dual mechanisms of protein mislocalization and promoter hypermethylation in breast cancer.
Lau QC, Raja E, Salto-Tellez M, Liu Q, Ito K, Inoue M, Putti TC, Loh M, Ko TK, Huang C, Bhalla KN, Zhu T, Ito Y, Sukumar S
Cancer research 2006 Jul 1;66(13):6512-20
Cancer research 2006 Jul 1;66(13):6512-20
RUNX3, a novel tumor suppressor, is frequently inactivated in gastric cancer by protein mislocalization.
Ito K, Liu Q, Salto-Tellez M, Yano T, Tada K, Ida H, Huang C, Shah N, Inoue M, Rajnakova A, Hiong KC, Peh BK, Han HC, Ito T, Teh M, Yeoh KG, Ito Y
Cancer research 2005 Sep 1;65(17):7743-50
Cancer research 2005 Sep 1;65(17):7743-50
No comments: Submit comment
Supportive validation
- Submitted by
- Enzo Life Sciences (provider)
- Main image
- Experimental details
- Western blot analysis using MAb to RUNX3 (human) (R3-6E9) (Prod. No. ALX-803-318). Method: 0.2µg/ml of MAb to RUNX3 (human) (R3-6E9) were applied to the membrane on which recombinant human (lanes 1-3) or mouse (lanes 4-6) RUNX1, RUNX2Êor RUNX3 expressed in COS7 cells were loaded (see [1]).
- Submitted by
- Enzo Life Sciences (provider)
- Main image
- Experimental details
- Immunohistochemistry using MAb to RUNX3 (human) (R3-6E9) (Prod. No. ALX-803-318). Method: 2µg/ml of MAb to RUNX3 (human) (R3-6E9) were appliedÊto normal human gastic samples (paraffin sections) which were retrieved by autoclave at 105¡C for 15 min. in Dako solution (see [1]).