ABIN362453
antibody from antibodies-online
Targeting: AURKA
AIK, ARK1, AurA, BTAK, PPP1R47, STK15, STK6, STK7
Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations [0]
Submit
Validation data
Reference
Comment
Report error
- Product number
- ABIN362453 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Aurora Kinase A (AURKA) (pThr288) antibody
- Antibody type
- Polyclonal
- Antigen
- Peptide sequence around phosphorylation site of pThr288 (R-T-T (p) -L-M) derived from Human Aurora A. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
- Description
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatography using non-phosphopeptide corresponding to the phosphorylation site.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Epitope
- pThr288
- Isotype
- IgG
- Vial size
- 50 μL
- Concentration
- 1 mg/mL
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Submitted references The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore-microtubule attachment and in maintaining the spindle assembly checkpoint.
The mitotic serine/threonine kinase Aurora2/AIK is regulated by phosphorylation and degradation.
The war of the sex chromosomes.
A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers.
Hauf S, Cole RW, LaTerra S, Zimmer C, Schnapp G, Walter R, Heckel A, van Meel J, Rieder CL, Peters JM
The Journal of cell biology 2003 Apr 28;161(2):281-94
The Journal of cell biology 2003 Apr 28;161(2):281-94
The mitotic serine/threonine kinase Aurora2/AIK is regulated by phosphorylation and degradation.
Walter AO, Seghezzi W, Korver W, Sheung J, Lees E
Oncogene 2000 Oct 5;19(42):4906-16
Oncogene 2000 Oct 5;19(42):4906-16
The war of the sex chromosomes.
Ellis NA
Nature genetics 1998 Sep;20(1):9-10
Nature genetics 1998 Sep;20(1):9-10
A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers.
Bischoff JR, Anderson L, Zhu Y, Mossie K, Ng L, Souza B, Schryver B, Flanagan P, Clairvoyant F, Ginther C, Chan CS, Novotny M, Slamon DJ, Plowman GD
The EMBO journal 1998 Jun 1;17(11):3052-65
The EMBO journal 1998 Jun 1;17(11):3052-65
No comments: Submit comment
No validations: Submit validation data