NBP1-51843
antibody from Novus Biologicals
Targeting: AURKA
AIK, ARK1, AurA, BTAK, PPP1R47, STK15, STK6, STK7
Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [3]
- Immunohistochemistry [1]
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Validation data
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- Product number
- NBP1-51843 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NBP1-51843, RRID:AB_11012696
- Product name
- Rabbit Polyclonal Aurora A Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Concentration
- 0.56 mg/ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references Chromosome Segregation Is Biased by Kinetochore Size.
Loss of PKCδ Induces Prostate Cancer Resistance to Paclitaxel through Activation of Wnt/β-Catenin Pathway and Mcl-1 Accumulation.
Loss of FBXW7 and accumulation of MCL1 and PLK1 promote paclitaxel resistance in breast cancer.
Aurora kinase A gene copy number is associated with the malignant transformation of colorectal adenomas but not with the serrated neoplasia progression.
Contribution of Aurora-A and -B expression to DNA aneuploidy in gastric cancers.
Drpic D, Almeida AC, Aguiar P, Renda F, Damas J, Lewin HA, Larkin DM, Khodjakov A, Maiato H
Current biology : CB 2018 May 7;28(9):1344-1356.e5
Current biology : CB 2018 May 7;28(9):1344-1356.e5
Loss of PKCδ Induces Prostate Cancer Resistance to Paclitaxel through Activation of Wnt/β-Catenin Pathway and Mcl-1 Accumulation.
Flores ML, Castilla C, Gasca J, Medina R, Pérez-Valderrama B, Romero F, Japón MA, Sáez C
Molecular cancer therapeutics 2016 Jul;15(7):1713-25
Molecular cancer therapeutics 2016 Jul;15(7):1713-25
Loss of FBXW7 and accumulation of MCL1 and PLK1 promote paclitaxel resistance in breast cancer.
Gasca J, Flores ML, Giráldez S, Ruiz-Borrego M, Tortolero M, Romero F, Japón MA, Sáez C
Oncotarget 2016 Aug 16;7(33):52751-52765
Oncotarget 2016 Aug 16;7(33):52751-52765
Aurora kinase A gene copy number is associated with the malignant transformation of colorectal adenomas but not with the serrated neoplasia progression.
Casorzo L, Dell'Aglio C, Sarotto I, Risio M
Human pathology 2015 Mar;46(3):411-8
Human pathology 2015 Mar;46(3):411-8
Contribution of Aurora-A and -B expression to DNA aneuploidy in gastric cancers.
Honma K, Nakanishi R, Nakanoko T, Ando K, Saeki H, Oki E, Iimori M, Kitao H, Kakeji Y, Maehara Y
Surgery today 2014 Mar;44(3):454-61
Surgery today 2014 Mar;44(3):454-61
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: Aurora A Antibody [NBP1-51843] - Western blot analysis of HepG2, HEK 293, and COS cell lysate using Aurora A antibody at 1:1000.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Simple Western: Aurora A Antibody [NBP1-51843] - Simple Western lane view shows a specific band for Aurora A in 0.5 mg/ml of HeLa lysate. This experiment was performed under reducing conditions using the 12-230kDa separation system.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: Aurora A Antibody [NBP1-51843] - WB detection of Aurora A in HeLa whole cell lysate.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry: Aurora A Antibody [NBP1-51843] - IHC staining of Aurora A in mouse brain.