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- Antigen structure
- References [15]
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- Product number
- 19117-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#19117-1-AP, RRID:AB_10640575
- Product name
- CDK6 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated CDK6 antibody (Cat. #19117-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references D-type cyclins regulate DNA mismatch repair in the G1 and S phases of the cell cycle, maintaining genome stability.
CDK-independent role of D-type cyclins in regulating DNA mismatch repair.
P16(INK4a) Regulates ROS-Related Autophagy and CDK4/6-Mediated Proliferation: A New Target of Myocardial Regeneration Therapy.
Methamphetamine exposure drives cell cycle exit and aberrant differentiation in rat hippocampal-derived neurospheres.
Estrogen-induced circRNA, circPGR, functions as a ceRNA to promote estrogen receptor-positive breast cancer cell growth by regulating cell cycle-related genes.
A Patient-Derived Xenograft Model of Dedifferentiated Endometrial Carcinoma: A Proof-of-Concept Study for the Identification of New Molecularly Informed Treatment Approaches.
GLI1 reduces drug sensitivity by regulating cell cycle through PI3K/AKT/GSK3/CDK pathway in acute myeloid leukemia.
A Novel lncRNA ENST00000512916 Facilitates Cell Proliferation, Migration and Cell Cycle Progression in Ameloblastoma.
Oxymatrine Inhibits Renal Cell Carcinoma Progression by Suppressing β-Catenin Expression.
δ-Catenin regulates proliferation and apoptosis in renal cell carcinoma via promoting β-catenin nuclear localization and activating its downstream target genes.
LncRNA FEZF1-AS1 Promotes TGF-β2-Mediated Proliferation and Migration in Human Lens Epithelial Cells SRA01/04.
SUN1 silencing inhibits cell growth through G0/G1 phase arrest in lung adenocarcinoma.
Knockdown of asparagine synthetase by RNAi suppresses cell growth in human melanoma cells and epidermoid carcinoma cells.
High expression of N-myc (and STAT) interactor predicts poor prognosis and promotes tumor growth in human glioblastoma.
γ-Glutamylcyclotransferase Knockdown Inhibits Growth of Lung Cancer Cells Through G0/G1 Phase Arrest.
Rona G, Miwatani-Minter B, Zhang Q, Goldberg HV, Kerzhnerman MA, Howard JB, Simoneschi D, Lane E, Hobbs JW, Sassani E, Wang AA, Keegan S, Laverty DJ, Piett CG, Pongor LS, Xu ML, Andrade J, Thomas A, Sicinski P, Askenazi M, Ueberheide B, Fenyö D, Nagel ZD, Pagano M
bioRxiv : the preprint server for biology 2024 Jan 13;
bioRxiv : the preprint server for biology 2024 Jan 13;
CDK-independent role of D-type cyclins in regulating DNA mismatch repair.
Rona G, Miwatani-Minter B, Zhang Q, Goldberg HV, Kerzhnerman MA, Howard JB, Simoneschi D, Lane E, Hobbs JW, Sassani E, Wang AA, Keegan S, Laverty DJ, Piett CG, Pongor LS, Xu ML, Andrade J, Thomas A, Sicinski P, Askenazi M, Ueberheide B, Fenyö D, Nagel ZD, Pagano M
Molecular cell 2024 Apr 4;84(7):1224-1242.e13
Molecular cell 2024 Apr 4;84(7):1224-1242.e13
P16(INK4a) Regulates ROS-Related Autophagy and CDK4/6-Mediated Proliferation: A New Target of Myocardial Regeneration Therapy.
Sun J, Zhou L, Yang T, Deng B, Bao Y, Gu L, Wang H, Wang L
Oxidative medicine and cellular longevity 2023;2023:1696190
Oxidative medicine and cellular longevity 2023;2023:1696190
Methamphetamine exposure drives cell cycle exit and aberrant differentiation in rat hippocampal-derived neurospheres.
Wang S, Wang L, Bu Q, Wei Q, Jiang L, Dai Y, Zhang N, Kuang W, Zhao Y, Cen X
Frontiers in pharmacology 2023;14:1242109
Frontiers in pharmacology 2023;14:1242109
Estrogen-induced circRNA, circPGR, functions as a ceRNA to promote estrogen receptor-positive breast cancer cell growth by regulating cell cycle-related genes.
Wang L, Yi J, Lu LY, Zhang YY, Wang L, Hu GS, Liu YC, Ding JC, Shen HF, Zhao FQ, Huang HH, Liu W
Theranostics 2021;11(4):1732-1752
Theranostics 2021;11(4):1732-1752
A Patient-Derived Xenograft Model of Dedifferentiated Endometrial Carcinoma: A Proof-of-Concept Study for the Identification of New Molecularly Informed Treatment Approaches.
Lin CY, Wu RC, Huang CY, Lai CH, Chao AS, Li HP, Tsai CL, Kuek EJ, Hsu CL, Chao A
Cancers 2021 Nov 26;13(23)
Cancers 2021 Nov 26;13(23)
GLI1 reduces drug sensitivity by regulating cell cycle through PI3K/AKT/GSK3/CDK pathway in acute myeloid leukemia.
Zhou C, Du J, Zhao L, Liu W, Zhao T, Liang H, Fang P, Zhang K, Zeng H
Cell death & disease 2021 Mar 3;12(3):231
Cell death & disease 2021 Mar 3;12(3):231
A Novel lncRNA ENST00000512916 Facilitates Cell Proliferation, Migration and Cell Cycle Progression in Ameloblastoma.
Sun Y, Niu X, Wang G, Qiao X, Chen L, Zhong M
OncoTargets and therapy 2020;13:1519-1531
OncoTargets and therapy 2020;13:1519-1531
Oxymatrine Inhibits Renal Cell Carcinoma Progression by Suppressing β-Catenin Expression.
Jin Y, Liu J, Liu Y, Liu Y, Guo G, Yu S, An R
Frontiers in pharmacology 2020;11:808
Frontiers in pharmacology 2020;11:808
δ-Catenin regulates proliferation and apoptosis in renal cell carcinoma via promoting β-catenin nuclear localization and activating its downstream target genes.
Ju L, Shan L, Yin B, Song Y
Cancer medicine 2020 Mar;9(6):2201-2212
Cancer medicine 2020 Mar;9(6):2201-2212
LncRNA FEZF1-AS1 Promotes TGF-β2-Mediated Proliferation and Migration in Human Lens Epithelial Cells SRA01/04.
Wang Y, Chen L, Gu Y, Wang Y, Yuan Y, Zhu Q, Bi M, Gu S
Journal of ophthalmology 2019;2019:4736203
Journal of ophthalmology 2019;2019:4736203
SUN1 silencing inhibits cell growth through G0/G1 phase arrest in lung adenocarcinoma.
Huang W, Huang H, Wang L, Hu J, Song W
OncoTargets and therapy 2017;10:2825-2833
OncoTargets and therapy 2017;10:2825-2833
Knockdown of asparagine synthetase by RNAi suppresses cell growth in human melanoma cells and epidermoid carcinoma cells.
Li H, Zhou F, Du W, Dou J, Xu Y, Gao W, Chen G, Zuo X, Sun L, Zhang X, Yang S
Biotechnology and applied biochemistry 2016 May;63(3):328-33
Biotechnology and applied biochemistry 2016 May;63(3):328-33
High expression of N-myc (and STAT) interactor predicts poor prognosis and promotes tumor growth in human glioblastoma.
Meng D, Chen Y, Yun D, Zhao Y, Wang J, Xu T, Li X, Wang Y, Yuan L, Sun R, Song X, Huai C, Hu L, Yang S, Min T, Chen J, Chen H, Lu D
Oncotarget 2015 Mar 10;6(7):4901-19
Oncotarget 2015 Mar 10;6(7):4901-19
γ-Glutamylcyclotransferase Knockdown Inhibits Growth of Lung Cancer Cells Through G0/G1 Phase Arrest.
Lin Z, Xiong L, Zhou J, Wang J, Li Z, Hu H, Lin Q
Cancer biotherapy & radiopharmaceuticals 2015 Jun;30(5):211-6
Cancer biotherapy & radiopharmaceuticals 2015 Jun;30(5):211-6
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The CDK6 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human CDK6. This antibody recognizes human,mouse,rat antigen. The CDK6 antibody has been validated for the following applications: ELISA, WB analysis.
