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- Antibody Data
- Antigen structure
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- Product number
- M00446-1 - Provider product page
- Provider
- Boster Biological Technology
- Product name
- Anti-Raf1 Rabbit Monoclonal Antibody
- Antibody type
- Monoclonal
- Description
- Monoclonal antibody for Raf-1/RAF1 detection. Host: Rabbit.Size: 100ug/vial. Tested applications: IF, IHC, ICC, WB. Reactive species: Human, Mouse, Rat Raf-1/RAF1 information: Molecular Weight: 73052 MW; Subcellular Localization: Cytoplasm. Cell membrane. Mitochondrion. Nucleus. Colocalizes with RGS14 and BRAF in both the cytoplasm and membranes. Phosphorylation at Ser-259 impairs its membrane accumulation. Recruited to the cell membrane by the active Ras protein. Phosphorylation at Ser-338 and Ser-339 by PAK1 is required for its mitochondrial localization. Retinoic acid- induced Ser-621 phosphorylated form of RAF1 is predominantly localized at the nucleus; Tissue Specificity: In skeletal muscle, isoform 1 is more abundant than isoform 2.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Antibody clone number
- BEC-18
- Vial size
- 100ug/vial
- Concentration
- 0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
- Storage
- At -20°C for one year. Avoid repeated freezing and thawing.
Submitted references Rhodiola rosea L. Attenuates Cigarette Smoke and Lipopolysaccharide-Induced COPD in Rats via Inflammation Inhibition and Antioxidant and Antifibrosis Pathways.
Effects of combination treatment with transcranial magnetic stimulation and bone marrow mesenchymal stem cell transplantation or Raf inhibition on spinal cord injury in rats.
The role of Dectin-1/Raf-1 signal cascade in innate immune of human corneal epithelial cells against Aspergillus fumigatus infection.
Cui H, Liu X, Zhang J, Zhang K, Yao D, Dong S, Feng S, Yang L, Li Y, Wang H, Huang J, Wang J
Evidence-based complementary and alternative medicine : eCAM 2021;2021:6103158
Evidence-based complementary and alternative medicine : eCAM 2021;2021:6103158
Effects of combination treatment with transcranial magnetic stimulation and bone marrow mesenchymal stem cell transplantation or Raf inhibition on spinal cord injury in rats.
Feng S, Wang S, Sun S, Su H, Zhang L
Molecular medicine reports 2021 Apr;23(4)
Molecular medicine reports 2021 Apr;23(4)
The role of Dectin-1/Raf-1 signal cascade in innate immune of human corneal epithelial cells against Aspergillus fumigatus infection.
Zhao GQ, Lin J, Hu LT, Yin XN, Wang Q, Xu Q, Li H
International journal of ophthalmology 2016;9(10):1371-1375
International journal of ophthalmology 2016;9(10):1371-1375
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