ABIN362234

antibody from antibodies-online

Targeting: RAF1 c-Raf, CRAF, Raf-1

Western blot (Recommended by provider)

Antibody Data

Product number

ABIN362234

Provider

antibodies-online

Product name

anti-V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1) (pSer338) antibody

Antibody type

Polyclonal

Antigen

Peptide sequence around phosphorylation site of pSer338 (R-D-S (p) -S-Y) derived from Human RAF. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatography using non-phosphopeptide corresponding to the phosphorylation site.

Reactivity

Human, Mouse

Host

Rabbit

Epitope

pSer338

Isotype

IgG

Vial size

100 μL

Concentration

1 mg/mL

Storage

Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

References

Submitted references

The RAS/Raf1/MEK/ERK signaling pathway facilitates VSV-mediated oncolysis: implication for the defective interferon response in cancer cells.

Noser JA, Mael AA, Sakuma R, Ohmine S, Marcato P, Lee PW, Ikeda Y
Molecular therapy : the journal of the American Society of Gene Therapy 2007 Aug;15(8):1531-6

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Positive regulation of Raf1-MEK1/2-ERK1/2 signaling by protein serine/threonine phosphatase 2A holoenzymes.

Adams DG, Coffee RL Jr, Zhang H, Pelech S, Strack S, Wadzinski BE
The Journal of biological chemistry 2005 Dec 30;280(52):42644-54

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Ras/Raf1-dependent signal in sphingosine-1-phosphate-induced tube formation in human coronary artery endothelial cells.

Miura S, Tanigawa H, Matsuo Y, Fujino M, Kawamura A, Saku K
Biochemical and biophysical research communications 2003 Jul 11;306(4):924-9