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- Product number
- ABIN358442 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1) (pSer339) antibody
- Antibody type
- Polyclonal
- Description
- Protein A Chromatography followed by two-step phosphospecific peptide affinity purification.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- pSer339
- Vial size
- 0.4 mL
- Storage
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Germline gain-of-function mutations in RAF1 cause Noonan syndrome.
Gain-of-function RAF1 mutations cause Noonan and LEOPARD syndromes with hypertrophic cardiomyopathy.
Razzaque MA, Nishizawa T, Komoike Y, Yagi H, Furutani M, Amo R, Kamisago M, Momma K, Katayama H, Nakagawa M, Fujiwara Y, Matsushima M, Mizuno K, Tokuyama M, Hirota H, Muneuchi J, Higashinakagawa T, Matsuoka R
Nature genetics 2007 Aug;39(8):1013-7
Nature genetics 2007 Aug;39(8):1013-7
Gain-of-function RAF1 mutations cause Noonan and LEOPARD syndromes with hypertrophic cardiomyopathy.
Pandit B, Sarkozy A, Pennacchio LA, Carta C, Oishi K, Martinelli S, Pogna EA, Schackwitz W, Ustaszewska A, Landstrom A, Bos JM, Ommen SR, Esposito G, Lepri F, Faul C, Mundel P, López Siguero JP, Tenconi R, Selicorni A, Rossi C, Mazzanti L, Torrente I, Marino B, Digilio MC, Zampino G, Ackerman MJ, Dallapiccola B, Tartaglia M, Gelb BD
Nature genetics 2007 Aug;39(8):1007-12
Nature genetics 2007 Aug;39(8):1007-12
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