ABIN362156

antibody from antibodies-online

Targeting: PAK1

Western blot (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN362156

Provider

antibodies-online

Product name

anti-P21-Activated Kinase 1 (PAK1) (pThr212) antibody

Antibody type

Polyclonal

Antigen

Peptide sequence around phosphorylation site of pThr212 (P-V-T (p) -P-T) derived from Human PAK1. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatography using non-phosphopeptide corresponding to the phosphorylation site.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Epitope

pThr212

Isotype

IgG

Vial size

100 μL

Concentration

1 mg/mL

Storage

Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

References

Submitted references

Cellular senescence requires CDK5 repression of Rac1 activity.

Alexander K, Yang HS, Hinds PW
Molecular and cellular biology 2004 Apr;24(7):2808-19

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Cell cycle-regulated phosphorylation of p21-activated kinase 1.

Thiel DA, Reeder MK, Pfaff A, Coleman TR, Sells MA, Chernoff J
Current biology : CB 2002 Jul 23;12(14):1227-32

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Phosphorylation of Pak1 by the p35/Cdk5 kinase affects neuronal morphology.

Rashid T, Banerjee M, Nikolic M
The Journal of biological chemistry 2001 Dec 28;276(52):49043-52