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- Antibody Data
- Antigen structure
- References [5]
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- Product number
- ABIN358296 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-P21-Activated Kinase 1 (PAK1) (pThr212) antibody
- Antibody type
- Polyclonal
- Description
- Protein A Affinity Chromatography. Then, the antibody fraction is peptide affinity purified in a 2-step procedure with peptides. The antibody is eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- pThr212
- Vial size
- 0.4 mL
- Storage
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Phosphoinositide-dependent kinase 1 and p21-activated protein kinase mediate reactive oxygen species-dependent regulation of platelet-derived growth factor-induced smooth muscle cell migration.
The Down syndrome cell adhesion molecule (DSCAM) interacts with and activates Pak.
Phosphorylation of RhoGDI by Pak1 mediates dissociation of Rac GTPase.
Human immunodeficiency virus type 1 Tat regulates endothelial cell actin cytoskeletal dynamics through PAK1 activation and oxidant production.
p21-activated kinase-1 signaling mediates cyclin D1 expression in mammary epithelial and cancer cells.
Weber DS, Taniyama Y, Rocic P, Seshiah PN, Dechert MA, Gerthoffer WT, Griendling KK
Circulation research 2004 May 14;94(9):1219-26
Circulation research 2004 May 14;94(9):1219-26
The Down syndrome cell adhesion molecule (DSCAM) interacts with and activates Pak.
Li W, Guan KL
The Journal of biological chemistry 2004 Jul 30;279(31):32824-31
The Journal of biological chemistry 2004 Jul 30;279(31):32824-31
Phosphorylation of RhoGDI by Pak1 mediates dissociation of Rac GTPase.
DerMardirossian C, Schnelzer A, Bokoch GM
Molecular cell 2004 Jul 2;15(1):117-27
Molecular cell 2004 Jul 2;15(1):117-27
Human immunodeficiency virus type 1 Tat regulates endothelial cell actin cytoskeletal dynamics through PAK1 activation and oxidant production.
Wu RF, Gu Y, Xu YC, Mitola S, Bussolino F, Terada LS
Journal of virology 2004 Jan;78(2):779-89
Journal of virology 2004 Jan;78(2):779-89
p21-activated kinase-1 signaling mediates cyclin D1 expression in mammary epithelial and cancer cells.
Balasenthil S, Sahin AA, Barnes CJ, Wang RA, Pestell RG, Vadlamudi RK, Kumar R
The Journal of biological chemistry 2004 Jan 9;279(2):1422-8
The Journal of biological chemistry 2004 Jan 9;279(2):1422-8
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