BS60685
antibody from Bioworld Technology, Inc
Targeting: ZBTB7A
DKFZp547O146, FBI-1, LRF, pokemon, ZBTB7, ZNF857A
Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- BS60685 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- ZBTB7A polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide corresponding to residues in Human ZBTB7A
- Description
- LRF, formerly identified as Pokemon, is a poxvirus zinc finger (POZ) domain-containing transcription factor that influences cell differentiation. LRF (for leukemia/lymphoma related factor) is also known as zinc finger and BTB domain containing 7A, ZBTB7, TIP21, FBI1 and FBI-1. POZ-domain transcription factors contain a POZ or BTB type protein-protein interaction domain at their N-terminus and Kruppel-type zinc fingers at their C-terminus. LRF is inducible during both murine and human preadipocyte differentiation and may contrib-ute to adipogenesis through influencing the switch from cellular proliferation to terminal differentiation. LRF can associate with active chromatin and stimulate TAT-activated HIV-1 transcription through interactions with the HIV-1 long terminal repeat. 3T3L1 cells stably overexpressing LRF show a reduction in DNA synthesis and in expression of cyclin A, cyclin-dependent kinase 2 and p107.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
- Submitted by
- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- Western blot (WB) analysis of ZBTB7A pAb at 1:500 dilutionLane1:A549 whole cell lysateLane2:sp2/0 whole cell lysate Lane3:PC12 whole cell lysate