9111

antibody from Cell Signaling Technology, Inc

Targeting: CDK1 CDC2, CDC28A

Western blot (Data presented on provider website)

Immunoprecipitation (Data presented on provider website)

Antibody Data

Product number

9111

Provider

Cell Signaling Technology, Inc

Proper citation

Cell Signaling Technology Cat#9111, RRID:AB_331460

Product name

Phospho-cdc2 (Tyr15) Antibody

Antibody type

Polyclonal

Reactivity

Human, Mouse, Rat, Drosophila, Simian, Xenopus, Yeast

Host

Rabbit

Storage

-20°C

References

Submitted references

Therapeutic targeting of Chk1 in NSCLC stem cells during chemotherapy.

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Cell death and differentiation 2012 May;19(5):768-78

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Ptpcd-1 is a novel cell cycle related phosphatase that regulates centriole duplication and cytokinesis.

Zineldeen DH, Shimada M, Niida H, Katsuno Y, Nakanishi M
Biochemical and biophysical research communications 2009 Mar 13;380(3):460-6

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S6K1 is involved in polyploidization through its phosphorylation at Thr421/Ser424.

Ma D, Yu H, Lin D, Sun Y, Liu L, Liu Y, Dai B, Chen W, Cao J
Journal of cellular physiology 2009 Apr;219(1):31-44

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Tumor cell cycle arrest induced by shear stress: Roles of integrins and Smad.

Chang SF, Chang CA, Lee DY, Lee PL, Yeh YM, Yeh CR, Cheng CK, Chien S, Chiu JJ
Proceedings of the National Academy of Sciences of the United States of America 2008 Mar 11;105(10):3927-32

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Depletion of Chk1 leads to premature activation of Cdc2-cyclin B and mitotic catastrophe.

Niida H, Tsuge S, Katsuno Y, Konishi A, Takeda N, Nakanishi M
The Journal of biological chemistry 2005 Nov 25;280(47):39246-52

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The EBNA-3 gene family proteins disrupt the G2/M checkpoint.

Krauer KG, Burgess A, Buck M, Flanagan J, Sculley TB, Gabrielli B
Oncogene 2004 Feb 19;23(7):1342-53

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PKN delays mitotic timing by inhibition of Cdc25C: possible involvement of PKN in the regulation of cell division.

Misaki K, Mukai H, Yoshinaga C, Oishi K, Isagawa T, Takahashi M, Ohsumi K, Kishimoto T, Ono Y
Proceedings of the National Academy of Sciences of the United States of America 2001 Jan 2;98(1):125-9

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Loss of a protein phosphatase 2A regulatory subunit (Cdc55p) elicits improper regulation of Swe1p degradation.

Yang H, Jiang W, Gentry M, Hallberg RL
Molecular and cellular biology 2000 Nov;20(21):8143-56

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Absence of Wee1 ensures the meiotic cell cycle in Xenopus oocytes.

Nakajo N, Yoshitome S, Iwashita J, Iida M, Uto K, Ueno S, Okamoto K, Sagata N
Genes & development 2000 Feb 1;14(3):328-38

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c-Mos forces the mitotic cell cycle to undergo meiosis II to produce haploid gametes.

Tachibana K, Tanaka D, Isobe T, Kishimoto T
Proceedings of the National Academy of Sciences of the United States of America 2000 Dec 19;97(26):14301-6

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Aberrant expression of mitotic cdc2/cyclin B1 kinase in degenerating neurons of Alzheimer's disease brain.

Vincent I, Jicha G, Rosado M, Dickson DW
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997 May 15;17(10):3588-98