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Western blot
Immunocytochemistry
Other assayAntibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Other assay [2]
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- Product number
- MA5-11469 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- Anti-CDK1 Monoclonal Antibody (A17.1.1), Biotin
- Antibody type
- Monoclonal
- Antigen
- Other
- Description
- MA5-11472 targets Cdk1 in ICC/IF, IHC (P), IP, and WB applications and shows reactivity with Chicken, Guinea Pig, Human, mouse, Rodent, Rat, and Xenopus laevis samples. The MA5-11472 immunogen is c-Terminal 2/3 of Xenopus CDC2 expressed in E. coli.
- Reactivity
- Human, Mouse, Rat, Chicken/Avian, Guinea Pig, Xenopus
- Host
- Mouse
- Conjugate
- Biotin
- Isotype
- IgG
- Antibody clone number
- A17.1.1
- Vial size
- 500 µL
- Concentration
- 0.2 mg/ml
- Storage
- 4° C
Submitted references Activated Akt as an indicator of prognosis in gastric cancer.
Ixocarpalactone A isolated from the Mexican tomatillo shows potent antiproliferative and apoptotic activity in colon cancer cells.
Prognostic significance of expressions of cell-cycle regulatory proteins in gastrointestinal stromal tumor and the relevance of the risk grade.
In vitro and in vivo pharmacokinetic-pharmacodynamic relationships for the trisubstituted aminopurine cyclin-dependent kinase inhibitors olomoucine, bohemine and CYC202.
The Cyclin-dependent kinase inhibitor CYC202 (R-roscovitine) inhibits retinoblastoma protein phosphorylation, causes loss of Cyclin D1, and activates the mitogen-activated protein kinase pathway.
c-Myc alters the DNA damage-induced G2/M arrest in human mammary epithelial cells.
Mitotic cell cycle proteins increase in podocytes despite lack of proliferation.
A novel, extraneuronal role for cyclin-dependent protein kinase 5 (CDK5): modulation of cAMP-induced apoptosis in rat leukemia cells.
Expression of the ALK protein by anaplastic large-cell lymphomas correlates with high proliferative activity.
Expression of p34(cdc2) and cyclins A and B compared to other proliferative features of non-Hodgkin's lymphomas: a multivariate cluster analysis.
Retinoblastoma-related p107 and pRb2/p130 proteins in malignant lymphomas: distinct mechanisms of cell growth control.
Cinti C, Vindigni C, Zamparelli A, La Sala D, Epistolato MC, Marrelli D, Cevenini G, Tosi P
Virchows Archiv : an international journal of pathology 2008 Nov;453(5):449-55
Virchows Archiv : an international journal of pathology 2008 Nov;453(5):449-55
Ixocarpalactone A isolated from the Mexican tomatillo shows potent antiproliferative and apoptotic activity in colon cancer cells.
Choi JK, Murillo G, Su BN, Pezzuto JM, Kinghorn AD, Mehta RG
The FEBS journal 2006 Dec;273(24):5714-23
The FEBS journal 2006 Dec;273(24):5714-23
Prognostic significance of expressions of cell-cycle regulatory proteins in gastrointestinal stromal tumor and the relevance of the risk grade.
Nakamura N, Yamamoto H, Yao T, Oda Y, Nishiyama K, Imamura M, Yamada T, Nawata H, Tsuneyoshi M
Human pathology 2005 Jul;36(7):828-37
Human pathology 2005 Jul;36(7):828-37
In vitro and in vivo pharmacokinetic-pharmacodynamic relationships for the trisubstituted aminopurine cyclin-dependent kinase inhibitors olomoucine, bohemine and CYC202.
Raynaud FI, Whittaker SR, Fischer PM, McClue S, Walton MI, Barrie SE, Garrett MD, Rogers P, Clarke SJ, Kelland LR, Valenti M, Brunton L, Eccles S, Lane DP, Workman P
Clinical cancer research : an official journal of the American Association for Cancer Research 2005 Jul 1;11(13):4875-87
Clinical cancer research : an official journal of the American Association for Cancer Research 2005 Jul 1;11(13):4875-87
The Cyclin-dependent kinase inhibitor CYC202 (R-roscovitine) inhibits retinoblastoma protein phosphorylation, causes loss of Cyclin D1, and activates the mitogen-activated protein kinase pathway.
Whittaker SR, Walton MI, Garrett MD, Workman P
Cancer research 2004 Jan 1;64(1):262-72
Cancer research 2004 Jan 1;64(1):262-72
c-Myc alters the DNA damage-induced G2/M arrest in human mammary epithelial cells.
Sheen JH, Woo JK, Dickson RB
British journal of cancer 2003 Oct 20;89(8):1479-85
British journal of cancer 2003 Oct 20;89(8):1479-85
Mitotic cell cycle proteins increase in podocytes despite lack of proliferation.
Petermann AT, Pippin J, Hiromura K, Monkawa T, Durvasula R, Couser WG, Kopp J, Shankland SJ
Kidney international 2003 Jan;63(1):113-22
Kidney international 2003 Jan;63(1):113-22
A novel, extraneuronal role for cyclin-dependent protein kinase 5 (CDK5): modulation of cAMP-induced apoptosis in rat leukemia cells.
Sandal T, Stapnes C, Kleivdal H, Hedin L, Døskeland SO
The Journal of biological chemistry 2002 Jun 7;277(23):20783-93
The Journal of biological chemistry 2002 Jun 7;277(23):20783-93
Expression of the ALK protein by anaplastic large-cell lymphomas correlates with high proliferative activity.
Leoncini L, Lazzi S, Scano D, Mura A, Onida A, Massarelli G, Tosi P, Barbini P, Cevenini G, Massai MR, Pileri S, Falini B, Giordano A, Kraft R, Laissue JA, Cottier H
International journal of cancer 2000 Jun 15;86(6):777-81
International journal of cancer 2000 Jun 15;86(6):777-81
Expression of p34(cdc2) and cyclins A and B compared to other proliferative features of non-Hodgkin's lymphomas: a multivariate cluster analysis.
Leoncini L, Cossu A, Megha T, Bellan C, Lazzi S, Luzi P, Tosi P, Barbini P, Cevenini G, Pileri S, Giordano A, Kraft R, Laissue JA, Cottier H
International journal of cancer 1999 Oct 8;83(2):203-9
International journal of cancer 1999 Oct 8;83(2):203-9
Retinoblastoma-related p107 and pRb2/p130 proteins in malignant lymphomas: distinct mechanisms of cell growth control.
Leoncini L, Bellan C, Cossu A, Claudio PP, Lazzi S, Cinti C, Cevenini G, Megha T, Laurini L, Luzi P, Orcioni GF, Piccioli M, Pileri S, Giardino C, Tosi P, Giordano A
Clinical cancer research : an official journal of the American Association for Cancer Research 1999 Dec;5(12):4065-72
Clinical cancer research : an official journal of the American Association for Cancer Research 1999 Dec;5(12):4065-72
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunoprecipitation of Cdk1 using Cdk1 Monoclonal Antibody (Product # MA5-11469) on denatured Human HeLa Cells.
- Conjugate
- Biotin
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunoprecipitation of Cdk1 using Cdk1 Monoclonal Antibody (Product # MA5-11469) on Native Human HeLa Cells.
- Conjugate
- Biotin
